PIMA535606

GRP78 Recombinant Rabbit Monoclonal Antibody (ARC1141), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA535606-Each-of-1 In Stock ₹ 45,646.26

PIMA535606 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

GRP78

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P11021, P20029

Gene Symbols

Hspa5

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BiP/GRP78 (NP_0053381)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Clone

ARC1141

Conjugate

Unconjugated

Gene

Hspa5

Gene Alias

78 kDa glucose-regulated protein; 78 kDa glucose-regulated protein homolog; 78-kD glucose-regulated protein precursor; AL022860; AU019543; baffled; Binding-immunoglobulin protein; bip; BiP protein; BiP/Grp78; cb865; D2Wsu141e; D2Wsu17e; Endoplasmic reticulum chaperone BiP; endoplasmic reticulum chaperone BiP; 78 kDa glucose-regulated protein; endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; epididymis secretory sperm binding protein Li 89n; fb60h09; fi36d04; FLJ26106; glucose regulated protein, 78 kDa; glucose-regulated protein; glucose-regulated protein, 78kDa; GRP 78; grp78; GRP-78; heat shock 70 kDa protein 5; heat shock 70 kDa protein 5a; heat shock 70kD protein 5; heat shock 70kD protein 5 (glucose-regulated protein, 78kD); heat shock 70kDa protein 5; heat shock 70kDa protein 5 (glucose-regulated protein); heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); heat shock protein 5; heat shock protein 70 family protein 5; heat shock protein family A (Hsp70) member 5; heat shock protein family A (Hsp70) member 5 L homeolog; heat shock protein family A member 5; heavy-chain binding protein BiP; HEL-S-89n; Hsce70; hsp70; Hsp70 family ATPase KAR2; HSP70 family protein 5; HSPA 5; HSPA5; hspa5.L; hspa5a; I79_019946; immunoglobulin binding protein; immunoglobulin heavy chain-binding protein; Immunoglobulin heavy chain-binding protein homolog; J1248; KAR2; mBiP; MIF2; Sez7; SEZ-7; SSD1; Steroidogenesis-activator polypeptide; wu:fb60h09; wu:fi36d04; XAP-1; XAP-1 antigen; XELAEV_180384511mg; YJL034W; zgc:55994; zgc:77606

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14828, 3309

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Description

  • Immunogen sequence: MKLSLVAAML LLLSAARAEE EDKKEDVGTV VGIDLGTTYS CVGVFKNGRV EIIANDQGNR ITPSYVAFTP EGERLIGDAA KNQLTSNPEN TVFDAKRLIG GRP78 is a 78 kDa glucose regulated protein that belongs to the family of heat shock proteins that include HSP70
  • GRP78 is a resident protein of the endoplasmic reticulum (ER) and associates transiently with a variety of newly synthesized secretory and membrane proteins
  • GRP78 may also interact with mutant and misfolded proteins, marking them for degradation
  • The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the C-terminus of GRP78 and other resident ER proteins including glucose regulated protein 94 (GRP94) and protein disulfide isomerase (PDI)
  • The KDEL signal is recognized by the KDEL receptor and this interaction ensures recycling of escaped ER proteins back to the ER
  • GRP78’s involvement in correct folding of proteins and degradation of misfolded proteins is via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate
  • GRP78 is critical for maintenance of cell homeostasis and the prevention of apoptosis
  • GRP78 protein levels have been shown to be a reliable biomarker of hypoglycemia and serves a neuroprotective function in neurons exposed to glutamate and oxidative stress
  • GRP78 levels are reduced in the brains of Alzheimer's Disease patients, and decreased expression of GRP78 is found associated with missense mutations in the human presenilin-1 (PS1) gene
  • Further, the induction of the GRP78 protein has been associated with the development of drug-resistance to antitumor drugs.

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Img

Thermo Scientific

PIMA535606

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Antigen:
GRP78

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P11021, P20029

Gene Symbols:
Hspa5

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BiP/GRP78 (NP_0053381)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
ARC1141

Conjugate:
Unconjugated

Gene:
Hspa5

Gene Alias:
78 kDa glucose-regulated protein; 78 kDa glucose-regulated protein homolog; 78-kD glucose-regulated protein precursor; AL022860; AU019543; baffled; Binding-immunoglobulin protein; bip; BiP protein; BiP/Grp78; cb865; D2Wsu141e; D2Wsu17e; Endoplasmic reticulum chaperone BiP; endoplasmic reticulum chaperone BiP; 78 kDa glucose-regulated protein; endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; epididymis secretory sperm binding protein Li 89n; fb60h09; fi36d04; FLJ26106; glucose regulated protein, 78 kDa; glucose-regulated protein; glucose-regulated protein, 78kDa; GRP 78; grp78; GRP-78; heat shock 70 kDa protein 5; heat shock 70 kDa protein 5a; heat shock 70kD protein 5; heat shock 70kD protein 5 (glucose-regulated protein, 78kD); heat shock 70kDa protein 5; heat shock 70kDa protein 5 (glucose-regulated protein); heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); heat shock protein 5; heat shock protein 70 family protein 5; heat shock protein family A (Hsp70) member 5; heat shock protein family A (Hsp70) member 5 L homeolog; heat shock protein family A member 5; heavy-chain binding protein BiP; HEL-S-89n; Hsce70; hsp70; Hsp70 family ATPase KAR2; HSP70 family protein 5; HSPA 5; HSPA5; hspa5.L; hspa5a; I79_019946; immunoglobulin binding protein; immunoglobulin heavy chain-binding protein; Immunoglobulin heavy chain-binding protein homolog; J1248; KAR2; mBiP; MIF2; Sez7; SEZ-7; SSD1; Steroidogenesis-activator polypeptide; wu:fb60h09; wu:fi36d04; XAP-1; XAP-1 antigen; XELAEV_180384511mg; YJL034W; zgc:55994; zgc:77606

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14828, 3309

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535607

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Antigen:
Cytochrome C

Classification:
Monoclonal

Concentration:
0.8 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P62897, P62898, P99999

Gene Symbols:
Cycs

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-105 of human Cytochrome C (P99999)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
ARC1153

Conjugate:
Unconjugated

Gene:
Cycs

Gene Alias:
CG17903; CG17903-PA; CG17903-PB; CRF; CYC; CYC2; Cycs; CYCSA; Cyct-c-p; Cyt c; cyt c-p; cyt.c; CytC; Cyt-c; CYTC2; Cyt-c2; CytC-2; cyt-c-p; cytC-p; Cyt-c-p-PA; Cyt-c-p-PB; Cytochrome c; cytochrome c DC4; Cytochrome c proximal; Cytochrome C, expressed in somatic tissues; cytochrome c, somatic; Cytochrome c-2; cytochrome c-like; cytochrome c-like protein; Cytochrome c-proximal; cytochrome-c-p; Cytochrome-c-proximal; DC4; dCyt.C-p; DMc01; Dmel\CG17903; Dmel_CG17903; hc1; HCS; l(2)k13905; lethal (2) k13905; LOC100341175; LOC100357840; MGC128356 protein; pDMc01; RH17228p; THC4

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13063, 25309, 54205

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535611

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Antigen:
PRDX1

Classification:
Monoclonal

Concentration:
0.34 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P35700, Q06830

Gene Symbols:
PRDX1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Peroxiredoxin 1/PAG (Q06830)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ARC1274

Conjugate:
Unconjugated

Gene:
PRDX1

Gene Alias:
ACR1; Alu co-repressor 1; AOEB166; B166; HBP23; heme-binding 23 kDa protein; macrophage 23 Kd stress protein; macrophage 23 kDa stress protein; macrophage 23kDa stress protein; macrophase stress protein 22kDa; macrophase stress protein 23 kd; Msp23; Natural killer cell-enhancing factor A; natural killer-enhancing factor A; NkefA; NKEF-A; OSF3; OSF-3; osteoblast specific factor 3; osteoblast-specific factor 3; PAG; Paga; PAGB; peroxiredoxin 1; peroxiredoxin-1; PRDX1; PrdxI; proliferation-associated gene A; proliferation-associated gene protein; Prx; Prx 1; PRX1; PRXI; TDPX2; TDX2; thioredoxin dependent peroxide reductase 2; thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2; TPxA; Trx dependent peroxide reductase 2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18477, 5052

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535613

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Antigen:
Myosin Heavy Chain

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P02563, P12882, P13533, Q02566, Q5SX40

Gene Symbols:
MYH1, Myh6

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1200-1400 of human Myosin heavy chain (P12883)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
6V0G1

Conjugate:
Unconjugated

Gene:
MYH1

Gene Alias:
A530084A17Rik; A830009F23Rik; AA517445; alpha cardiac MHC; alpha myosin; alpha-MHC; ASD3; beta-myosin heavy chain; Bsh; cardiac myosin heavy chain alpha isoform; cardiomyopathy, hypertrophic 1; CG17927; CG17927-PA; CG17927-PB; CG17927-PC; CG17927-PD; CG17927-PE; CG17927-PF; CG17927-PG; CG17927-PH; CG17927-PI; CG17927-PK; CG17927-PL; CG17927-PM; CG17927-PN; CG17927-PO; CG17927-PP; CG17927-PQ; CG17927-PR; CG17927-PS; CG17927-PT; CG17927-PU; CG17927-PV; chain; chr2L:16765388..16765564; chr2L:16781880..16782040; CMD1EE; CMH14; DFNA4; DFNA4A; Dm II; Dmel\CG17927; Dmel_CG17927; DmMHC; DROMHC; DroMII; epididymis luminal protein 71; FP17425; heavy chain; HEL71; ifm(2)2; ifm(2)RU1; ifm(2)RU2; IId; IId/x; indirect flight muscle (2) RU1; indirect flight muscle (2) RU2; KIAA2034; l(2)36Ae; l(2)k10423; l(2)M66; MdMs; mhc; MHC16; MHC2X/D; MHC-2X/D; Mhc36B; Mhc-PA; Mhc-PB; Mhc-PC; Mhc-PD; Mhc-PE; Mhc-PF; Mhc-PG; Mhc-PH; Mhc-PI; Mhc-PK; Mhc-PL; Mhc-PM; Mhc-PN; Mhc-PO; Mhc-PP; Mhc-PQ; Mhc-PR; Mhc-PS; Mhc-PT; Mhc-PU; Mhc-PV; mMHC; MRP; muscle myosin; muscle myosin heavy chain; muscle myosin II; muscle myosin II heavy chain; muscle myosin-II; muscle specific myosin II; MYH1; MYH14; MYH14 variant protein; MYH17; MYH6; MYHa; MYHC; MyHC-2x; MyHC-2X/D; Myhca; Myhc-a; MyHC-alpha; MyHC-IId/x; MYHC-IIX; myHC-IIx/d; MYHSA1; Myhs-f; Myhsf2; Myhs-f2; Myo; Myo6; myosin; myosin HC; myosin heavy; myosin heavy chain; myosin heavy chain 1; Myosin heavy chain 14; Myosin heavy chain 2x; myosin heavy chain 6; Myosin heavy chain IIx/d; myosin heavy chain polypeptide 6 cardiac muscle adult; myosin heavy chain, cardiac muscle alpha isoform; Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha); myosin heavy chain, cardiac muscle, adult; Myosin heavy chain, muscle; Myosin heavy chain, non-muscle IIc; myosin heavy chain, polypeptide 6, cardiac muscle, alpha; myosin heavy chain, skeletal muscle, adult 1; myosin heavy Chain-PF; myosin heavy-chain; myosin heavy-chain protein; myosin II heavy chain; myosin rod protein; myosin, heavy chain 1, skeletal muscle, adult; myosin, heavy chain 14, non-muscle; myosin, heavy chain 6, cardiac muscle, alpha; myosin, heavy polypeptide 1, skeletal muscle, adult; myosin, heavy polypeptide 14; myosin, heavy polypeptide 6, cardiac muscle, alpha; myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1); myosin-1; Myosin-14; myosin-6; myosin-heavy chain; NMHC II-C; NMHC-II-C; non-muscle myosin heavy chain IIc; nonmuscle myosin heavy chain II-C; Not-upheld; Nup; PNMHH; samba; sarcomeric myosin heavy-chain; shrunken thorax; Shrunken-thorax; Sht; sMHC; SSS3; Stp; stuckup; type 2X myosin heavy chain

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17879, 17888, 287408, 29556, 4619, 4624

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid