PIMA535633

PSME1 Recombinant Rabbit Monoclonal Antibody (ARC1254), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA535633-Each-of-1 In Stock ₹ 45,646.26

PIMA535633 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

PSME1

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P97371, Q06323, Q63797

Gene Symbols

PSME1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human PSME1(NP_0062541)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Clone

ARC1254

Conjugate

Unconjugated

Gene

PSME1

Gene Alias

11S regulator complex subunit alpha; 29-kD MCP activator subunit; activator of multicatalytic protease subunit 1; AW413925; epididymis secretory sperm binding protein Li 129m; HEL-S-129m; I79_008549; IFI5111; IGUP I-5111; interferon gamma up-regulated I-5111 protein; interferon-gamma IEF SSP 5111; interferon-gamma-inducible protein 5111; MGC8628; OTTHUMP00000164702; PA28 alpha subunit; PA28a; PA28alpha; protease (prosome, macropain) 28 subunit, alpha; proteasome (prosome, macropain) 28 subunit, alpha; proteasome (prosome, macropain) activator subunit 1; proteasome (prosome, macropain) activator subunit 1 (PA28 alpha); proteasome activator 28 subunit alpha; Proteasome activator complex subunit 1; proteasome activator subunit 1; Psme1; REGalpha; REG-alpha

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19186, 29630, 5720

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Immunogen sequence: MAMLRVQPEA QAKVDVFRED LCTKTENLLG SYFPKKISEL DAFLKEPALN EANLSNLKAP LDIPVPDPVK EKEKEERKKQ QEKEDKDEKK KGEDEDKGPP CGPVNCNEKI VVLLQ Proteolytic degradation is critical to the maintenance of appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cellular metabolism, heat shock and stress response, antigen presentation, modulation of cell surface receptors and ion channels, cell cycle regulation, transcription, and signalling factors
  • The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus
  • Others are degraded via the vacuolar pathway which includes endosomes, lysosomes, and the endoplasmic reticulum
  • The 26S proteasome is an ATP-dependent, multisubunit (approximately 31), barrel-shaped molecular machine with an apparent molecular weight of approximately 2.5 MDa
  • It consists of a 20S proteolytic core complex which is crowned at one or both ends by 19S regulatory subunit complexes
  • The 19S regulatory subunits recognize ubiquitinated proteins and play an essential role in unfolding and translocating targets into the lumen of the 20S subunit
  • An enzymatic cascade is responsible for the attachment of multiple ubiquitin molecules to lysine residues of proteins targeted for degradation
  • Several genetic diseases are associated with defects in the ubiquitin-proteasome pathway
  • Some examples of affected proteins include those linked to cystic fibrosis, Angelman's syndrome, and Liddle syndrome.

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Img

Thermo Scientific

PIMA535633

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Antigen:
PSME1

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P97371, Q06323, Q63797

Gene Symbols:
PSME1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human PSME1(NP_0062541)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ARC1254

Conjugate:
Unconjugated

Gene:
PSME1

Gene Alias:
11S regulator complex subunit alpha; 29-kD MCP activator subunit; activator of multicatalytic protease subunit 1; AW413925; epididymis secretory sperm binding protein Li 129m; HEL-S-129m; I79_008549; IFI5111; IGUP I-5111; interferon gamma up-regulated I-5111 protein; interferon-gamma IEF SSP 5111; interferon-gamma-inducible protein 5111; MGC8628; OTTHUMP00000164702; PA28 alpha subunit; PA28a; PA28alpha; protease (prosome, macropain) 28 subunit, alpha; proteasome (prosome, macropain) 28 subunit, alpha; proteasome (prosome, macropain) activator subunit 1; proteasome (prosome, macropain) activator subunit 1 (PA28 alpha); proteasome activator 28 subunit alpha; Proteasome activator complex subunit 1; proteasome activator subunit 1; Psme1; REGalpha; REG-alpha

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19186, 29630, 5720

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535634

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Antigen:
UPF1

Classification:
Monoclonal

Concentration:
0.4 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q92900, Q9EPU0

Gene Symbols:
UPF1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human UPF1/RENT1 (Q92900)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
ARC1268

Conjugate:
Unconjugated

Gene:
UPF1

Gene Alias:
ATP-dependent helicase RENT1; B430202H16Rik; delta helicase; FLJ43809; FLJ46894; HUPF1; KIAA0221; LOW QUALITY PROTEIN: regulator of nonsense transcripts 1; mUpf1; Nonsense mRNA reducing factor 1; NORF1; pNORF1; PNORF-1; Regulator of nonsense transcripts 1; Regulator of nonsense transcripts 1 (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog); Rent1; smg-2; smg-2 homolog, nonsense mediated mRNA decay factor; Upf1; UPF1 regulator of nonsense transcripts homolog; UPF1 regulator of nonsense transcripts homolog (yeast); UPF1 RNA helicase and ATPase; UPF1, RNA helicase and ATPase; Upflp; up-frameshift mutation 1 homolog; up-frameshift suppressor 1 homolog; wu:fi40f07; wu:fj48a01; yeast Upf1p homolog; zgc:55472

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19704, 5976, 684558

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535636

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Antigen:
RAC1/RAC2/RAC3

Classification:
Monoclonal

Concentration:
1.6 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P15153, P60763, P60764, P63000, P63001, Q05144, Q6RUV5

Gene Symbols:
Rac1, RAC2, Rac3

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-189 of human RAC1(P63000)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ARC1165

Conjugate:
Unconjugated

Gene:
Rac1

Gene Alias:
AI323801; AI452260; AL023026; Cell migration-inducing gene 5 protein; D5Ertd559e; EN-7; EN-7 protein; GTPase; Gx; HSPC022; MIG5; p21-Rac1; p21-Rac2; p21-Rac3; protein EN-7; rac; Rac family small GTPase 1; Rac family small GTPase 1 L homeolog; Rac family small GTPase 2; Rac family small GTPase 3; rac1; Rac-1; rac1.L; Rac1B; RAC2; Rac3; Ras-like protein TC25; RAS-related C3 botulinum substrate 1; RAS-related C3 botulinum substrate 2; RAS-related C3 botulinum substrate 3; ras-related C3 botulinum toxin substrate 1; ras-related C3 botulinum toxin substrate 1 (rho family small GTP binding protein Rac1); ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) L homeolog; ras-related C3 botulinum toxin substrate 2; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2); ras-related C3 botulinum toxin substrate 3; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3); Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2); rho family, small GTP binding protein Rac1; rho family, small GTP binding protein Rac3; small G protein; TC25; TC-25; XELAEV_18045321mg; Xrac

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
170758, 19353, 19354, 363875, 366957, 5879, 5880, 5881, 688319

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535637

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Antigen:
GATA2/GATA3

Classification:
Monoclonal

Concentration:
1.5 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O09100, P23769, P23771, P23772, Q924Y4

Gene Symbols:
GATA2, GATA3

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human GATA2/3 (NP_1160272)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ARC1209

Conjugate:
Unconjugated

Gene:
GATA3

Gene Alias:
DCML; EMBL:AAK51128.1}; endothelial transcription factor GATA-2; GATA binding protein 2; GATA binding protein 3; Gata2; Gata-2; gata2 {ECO:0000312; Gata3; Gata-3; GATA-binding factor 3; GATA-binding protein 2; GATA-binding protein 3; GATA-bindning protein 2; HDR; HDRS; IMD21; jal; MGC2346; MGC5199; MGC5445; MONOMAC; NFE1B; trans-acting T-cell-specific transcription factor GATA-3

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14461, 14462, 25159, 2624, 2625, 85471

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid