PIMA535652
TSC1 Recombinant Rabbit Monoclonal Antibody (ARC1236), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA535652-Each-of-1 | In Stock | ₹ 45,646.26 |
PIMA535652 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,646.26
GST (18%): ₹ 8,216.327
Total Price: ₹ 53,862.587
Antigen
TSC1
Classification
Monoclonal
Concentration
0.49 mg/mL
Formulation
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q92574
Gene Symbols
TSC1
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1065-1164 of human Hamartin (Q92574)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Clone
ARC1236
Conjugate
Unconjugated
Gene
TSC1
Gene Alias
hamartin; HGNC:12362; Kiaa0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; Tsc1; tuberous sclerosis 1; tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
7248
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Description
- Immunogen sequence: TTMGEASASI PTTVGSLPSS KSFLGMKARE LFRNKSESQC DEDGMTSSLS ESLKTELGKD LGVEAKIPLN LDGPHPSPPT PDSVGQLHIM DYNETHHEHS Tuberous sclerosis complex (TSC) is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 or TSC2 tumor suppressor genes
- The products of these genes form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors
- TOR activity is stimulated by Rheb, a member of the Ras superfamily of G-proteins, when the GTP/GDP ratio bound to Rheb is high
- Immunoprecipitated TSC1/TSC2 has been shown to stimulate Rheb GTPase activity in vitro, suggesting that the TSC1/TSC2 decreases the ability of Rheb to stimulate TOR activity
- This is supported by experiments showing overexpression of TSC1 and TSC2 results in a significant decrease in the GTP/GDP ratio bound to Rheb and the inhibition of cell growth
- A shorter 40 kDa isoform of TSC1 has been shown to exist but its function is unknown.
Compare Similar Items
Show Difference
Antigen: TSC1
Classification: Monoclonal
Concentration: 0.49 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q92574
Gene Symbols: TSC1
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1065-1164 of human Hamartin (Q92574)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: ARC1236
Conjugate: Unconjugated
Gene: TSC1
Gene Alias: hamartin; HGNC:12362; Kiaa0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; Tsc1; tuberous sclerosis 1; tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7248
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
TSC1
Classification:
Monoclonal
Concentration:
0.49 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q92574
Gene Symbols:
TSC1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1065-1164 of human Hamartin (Q92574)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
ARC1236
Conjugate:
Unconjugated
Gene:
TSC1
Gene Alias:
hamartin; HGNC:12362; Kiaa0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; Tsc1; tuberous sclerosis 1; tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7248
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: ICOS
Classification: Monoclonal
Concentration: 2 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q9R1T7, Q9WVS0, Q9Y6W8
Gene Symbols: ICOS
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ICOS/CD278 (Q9Y6W8)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: ARC1148
Conjugate: Unconjugated
Gene: ICOS
Gene Alias: Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 29851, 54167, 64545
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
ICOS
Classification:
Monoclonal
Concentration:
2 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q9R1T7, Q9WVS0, Q9Y6W8
Gene Symbols:
ICOS
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ICOS/CD278 (Q9Y6W8)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
ARC1148
Conjugate:
Unconjugated
Gene:
ICOS
Gene Alias:
Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
29851, 54167, 64545
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: LDHB
Classification: Monoclonal
Concentration: 0.6 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P07195, P42123
Gene Symbols: LDHB
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LDHB (P07195)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: ARC1217
Conjugate: Unconjugated
Gene: LDHB
Gene Alias: AI790582; epididymis secretory protein Li 281; H(B)-type lactate dehydrogenase; HEL-S-281; H-Ldh; lactate dehydrogenase B; lactate dehydrogenase H chain; lactate dehydrogenase-B; lactate dehydrogenase-H; lactate dehydrogenase-H (, EC 1.1.1.27); Lactate dehydrogenease B; LDH heart subunit; Ldh2; Ldh-2; LDHB; LDH-B; LDHBD; LDHH; LDH-H; L-lactate dehydrogenase B chain; Renal carcinoma antigen NY-REN-46; similar to lactate dehydrogenase B; testicular secretory protein Li 25; TRG-5
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 24534, 3945
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
LDHB
Classification:
Monoclonal
Concentration:
0.6 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P07195, P42123
Gene Symbols:
LDHB
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LDHB (P07195)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
ARC1217
Conjugate:
Unconjugated
Gene:
LDHB
Gene Alias:
AI790582; epididymis secretory protein Li 281; H(B)-type lactate dehydrogenase; HEL-S-281; H-Ldh; lactate dehydrogenase B; lactate dehydrogenase H chain; lactate dehydrogenase-B; lactate dehydrogenase-H; lactate dehydrogenase-H (, EC 1.1.1.27); Lactate dehydrogenease B; LDH heart subunit; Ldh2; Ldh-2; LDHB; LDH-B; LDHBD; LDHH; LDH-H; L-lactate dehydrogenase B chain; Renal carcinoma antigen NY-REN-46; similar to lactate dehydrogenase B; testicular secretory protein Li 25; TRG-5
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
24534, 3945
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: WASP
Classification: Monoclonal
Concentration: 0.72 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P42768, P70315
Gene Symbols: Was
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human WASP (P42768)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: ARC1204
Conjugate: Unconjugated
Gene: Was
Gene Alias: 2900021I12Rik; 3110031I02Rik; eczema-thrombocytopenia; IMD2; neural Wiskott-Aldrich syndrome protein; NWASP; N-WASP; SCNX; THC; THC1; thrombocytopenia 1 (X-linked); TRS4; U42471; Was; WASL; Wasp; WASPA; WASPB; Wiskott-Aldrich syndrome; Wiskott-Aldrich syndrome homolog; Wiskott-Aldrich syndrome homolog (human); Wiskott-Aldrich syndrome like; wiskott-Aldrich syndrome protein; Wiskott-Aldrich syndrome protein homolog; Wiskott-Aldrich syndrome-like; Wiskott-Aldrich syndrome-like (human)
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22376, 317371, 7454
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
WASP
Classification:
Monoclonal
Concentration:
0.72 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P42768, P70315
Gene Symbols:
Was
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human WASP (P42768)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
ARC1204
Conjugate:
Unconjugated
Gene:
Was
Gene Alias:
2900021I12Rik; 3110031I02Rik; eczema-thrombocytopenia; IMD2; neural Wiskott-Aldrich syndrome protein; NWASP; N-WASP; SCNX; THC; THC1; thrombocytopenia 1 (X-linked); TRS4; U42471; Was; WASL; Wasp; WASPA; WASPB; Wiskott-Aldrich syndrome; Wiskott-Aldrich syndrome homolog; Wiskott-Aldrich syndrome homolog (human); Wiskott-Aldrich syndrome like; wiskott-Aldrich syndrome protein; Wiskott-Aldrich syndrome protein homolog; Wiskott-Aldrich syndrome-like; Wiskott-Aldrich syndrome-like (human)
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22376, 317371, 7454
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid