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PIMA535749

PROX1 Recombinant Rabbit Monoclonal Antibody (ARC1391), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA535749-Each-of-1 In Stock ₹ 45,988.50

PIMA535749 - Each of 1

₹ 45,988.50

In Stock

Quantity

1

Base Price: ₹ 45,988.50

GST (18%): ₹ 8,277.93

Total Price: ₹ 54,266.43

Antigen

PROX1

Classification

Monoclonal

Concentration

0.80 mg/mL

Formulation

PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P48437, Q92786

Gene Symbols

Prox1

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PROX1 (Q92786)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

ARC1391

Conjugate

Unconjugated

Gene

Prox1

Gene Alias

A230003G05Rik; homeobox prospero-like protein PROX1; prospero homeobox 1; prospero homeobox protein 1; prospero-related homeobox 1; Prox 1; PROX1; PROX-1

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19130, 305066, 5629

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Description

  • Immunogen sequence: MPDHDSTALL SRQTKRRRVD IGVKRTVGTA SAFFAKARAT FFSAMNPQGS EQDVEYSVVQ HADGEKSNVL RKLLKRANSY EDAMMPFPGA TIISQLLKNN The expression pattern of the Prox1 homeo box gene suggests that it has a role in a variety of embryonic tissues, including lens
  • Analysis of mRNA reveals that Prox mRNA is present in many different human tissues and that lens demonstrated the highest level
  • Homozygous Prox1-null mice die at midgestation from multiple developmental defects, and a targeted effect on lens development has been reported
  • Prox1 inactivation caused abnormal cellular proliferation, downregulated expression of the cell cycle inhibitors Cdkn1b and Cdkn1c, misexpression of E-cadherin, and excessive apoptosis
  • Consequently, mutant lens cells failed to polarize and elongate properly, resulting in a hollow lens
  • The Prox1 gene is expressed in a subpopulation of endothelial cells that by budding and sprouting give rise to the lymphatic system
  • Prox1 appears to be a specific and required regulator of the development of the lymphatic system
  • Prox1 also has been document to be required for hepatocyte migration in the mouse
  • Loss of Prox1 results in a smaller liver with a reduced population of clustered hepatocytes
  • The homeodomain protein Prox1 regulates the egress of progenitor cells from the cell cycle in the embryonic mouse retina
  • Cells lacking Prox1 are less likely to stop dividing, and ectopic expression of Prox1 forces progenitor cells to exit the cell cycle
  • Prox1 acts as a key participant in progenitor-cell proliferation and cell-fate determination in the vertebrate retina.

Compare Similar Items

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Img

Thermo Scientific

PIMA535749

--

Antigen:
PROX1
Classification:
Monoclonal
Concentration:
0.80 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P48437, Q92786
Gene Symbols:
Prox1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PROX1 (Q92786)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
ARC1391
Conjugate:
Unconjugated
Gene:
Prox1
Gene Alias:
A230003G05Rik; homeobox prospero-like protein PROX1; prospero homeobox 1; prospero homeobox protein 1; prospero-related homeobox 1; Prox 1; PROX1; PROX-1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19130, 305066, 5629
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

Thermo Scientific

PIMA535751

--

Antigen:
SRSF3
Classification:
Monoclonal
Concentration:
1.25 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P84103, P84104
Gene Symbols:
SRSF3
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SRSF3 (P84103)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
ARC1394
Conjugate:
Unconjugated
Gene:
SRSF3
Gene Alias:
AL024116; pre-mRNA splicing factor SRp20; pre-mRNA-splicing factor SRP20; Protein X16; serine and arginine rich splicing factor 3; serine/arginine-rich splicing factor 3; SFRS3; splicing factor, arginine/serine-rich 3; splicing factor, arginine/serine-rich 3 (SRp20); splicing factor, arginine/serine-rich, 20-kD; Srp20; SRSF3; X16
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20383, 361814, 6428
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

Thermo Scientific

PIMA535752

--

Antigen:
Histone Macro-H2A.1
Classification:
Monoclonal
Concentration:
0.95 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
O75367, Q02874, Q9QZQ8
Gene Symbols:
MACROH2A1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human macroH2A1 (O75367)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
ARC1396
Conjugate:
Unconjugated
Gene:
MACROH2A1
Gene Alias:
Core histone macro-H2A.1; H2A histone family member Y; H2A histone family, member Y; H2A.y; H2A/y; H2AF12M; H2AFY; Histone H2A.y; histone macroH2A1; histone macroH2A1.1; histone macroH2A1.2; macroH2A1; MACROH2A1.1; macroH2A1.2; medulloblastoma antigen MU-MB-50.205; mH2A1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26914, 29384, 9555
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

Thermo Scientific

PIMA535753

--

Antigen:
FHIT
Classification:
Monoclonal
Concentration:
1.59 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
O89106, P49789, Q9JIX3
Gene Symbols:
FHIT
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FHIT (P49789)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
ARC1401
Conjugate:
Unconjugated
Gene:
FHIT
Gene Alias:
AP3A hydrolase; AP3Aase; AW045638; bis(5'-adenosyl)-triphosphatase; bis5'-adenosyl-triphosphatase; Diadenosine 5',5'''-P1,P3-triphosphate hydrolase; dinucleosidetriphosphatase; FHIT; Fra14A2; FRA3B; fragile histidine triad; fragile histidine triad gene; fragile histidine triad protein
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14198, 2272, 60398
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid