PIMA536117

RAP80 Monoclonal Antibody (A1B11), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA536117-Each-of-1 In Stock ₹ 45,646.26

PIMA536117 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

RAP80

Classification

Monoclonal

Concentration

2 mg/mL

Formulation

PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q5PQK4, Q5U5Q9, Q96RL1

Gene Symbols

UIMC1

Immunogen

Recombinant protein within Human RAP80 aa 330-524

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone

A1B11

Conjugate

Unconjugated

Gene

UIMC1

Gene Alias

9430016E08Rik; BRCA1-A complex subunit RAP80; D330018D10Rik; D630032M02Rik; RAP80; Receptor-associated protein 80; retinoid X receptor interacting protein 110; retinoid X receptor-interacting protein 110; RGD1307009; RIP110; Rxrip110; ubiquitin interaction motif containing 1; ubiquitin interaction motif-containing protein 1; Uimc1; X2HRIP110

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

20184, 290997, 51720

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • RAP80 was initially identified as zinc-finger containing nuclear protein that is highly expressed in testis and interacts with the retinoid-related testis-associated receptor (RTR)
  • Later experiments revealed that RAP80 is recruited by the Coiled-coil domain 98 (CCDC98) protein to the breast cancer-1 protein BRCA1, allowing the formation of BRCA1 foci in response to DNA damage caused by ionizing radiation
  • Both RAP80 and CCDC98 are required for DNA damage resistance, G2-M checkpoint control, and DNA repair
  • Cells depleted of either RAP80 or CCDC98 exhibited increased sensitivity to ionizing radiation, although not as much as in BRCA1-depleted cells, suggesting that RAP80 and CCDC98 control only part of the DNA damage response role of BRCA1
  • At least four isoforms of RAP80 are known to exist.

Compare Similar Items

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Img

Thermo Scientific

PIMA536117

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Antigen:
RAP80

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q5PQK4, Q5U5Q9, Q96RL1

Gene Symbols:
UIMC1

Immunogen:
Recombinant protein within Human RAP80 aa 330-524

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
A1B11

Conjugate:
Unconjugated

Gene:
UIMC1

Gene Alias:
9430016E08Rik; BRCA1-A complex subunit RAP80; D330018D10Rik; D630032M02Rik; RAP80; Receptor-associated protein 80; retinoid X receptor interacting protein 110; retinoid X receptor-interacting protein 110; RGD1307009; RIP110; Rxrip110; ubiquitin interaction motif containing 1; ubiquitin interaction motif-containing protein 1; Uimc1; X2HRIP110

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20184, 290997, 51720

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA536118

--


Antigen:
HMGB2

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P26583, P30681, P52925

Gene Symbols:
Hmgb2

Immunogen:
Recombinant protein within Human HMGB2 aa 1-209

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
10D1

Conjugate:
Unconjugated

Gene:
Hmgb2

Gene Alias:
C80539; high mobility group box 2; high mobility group protein 2; High mobility group protein B2; high-mobility group (nonhistone chromosomal) protein 2; high-mobility group box 2; HMG 2; HMG B2; Hmg2; HMG-2; HMGB2; HMG-B2; HMGB-2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
29395, 3148, 97165

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA536122

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Antigen:
CHI3L1

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P36222, Q61362

Gene Symbols:
CHI3L1, Chil1

Immunogen:
Synthetic peptide within Human YKL-40 aa 24-73

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
10C1

Conjugate:
Unconjugated

Gene:
CHI3L1

Gene Alias:
38 kDa heparin-binding glycoprotein; 38kDa heparin-binding glycoprotein; 39 kDa synovial protein; 39 kDa whey protein; 40 kDa secretory signalling glycoprotein; ASRT7; AW208766; BP40; BP40 precursor; breast regression protein 39; Brp39; BRP39 protein; Cartilage glycoprotein 39; cartilage glycoprotein-39; CGP39; CGP-39; CHI3L1; Chil1; chitinase 3 like 1; Chitinase 3 like protein 1CGP 39; chitinase 3-like 1; chitinase 3-like 1 (cartilage glycoprotein-39); chitinase 3-like 1 protein; chitinase-3-like protein 1; chitinase-like 1; chitinase-like protein 1; CLP-1; DKFZp686N19119; FLJ38139; GP38K; Gp39; GP-39; hCGP39; HC-gp39; hCGP-39; HCGP-3P; Mammary gland protein 40; MGP-40; signal processing protein; signal-processing protein; SPC-40; SPS-40; YKL40; YKL-40; YYL-40

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
1116, 12654

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA536124

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Antigen:
NuMA

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q14980

Gene Symbols:
NUMA1

Immunogen:
Recombinant protein within Human NuMA aa 1-200

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
A2H12

Conjugate:
Unconjugated

Gene:
NUMA1

Gene Alias:
6720401E04Rik; AA764025; AL022610; AU014979; centrophilin stabilizes mitotic spindle in mitotic cells; NMP22; NMP-22; Nuclear matrix protein-22; Nuclear mitotic apparatus protein; Nuclear mitotic apparatus protein 1; NUMA; NuMA protein; Numa1; SP-H antigen; structural nuclear protein

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
4926

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid