PIMA536893

Phospho-NPM1 (Ser4) Recombinant Rabbit Monoclonal Antibody (NPMS4-A1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA536893-Each-of-1 In Stock ₹ 31,742.76

PIMA536893 - Each of 1

₹ 31,742.76

In Stock

Quantity

1

Base Price: ₹ 31,742.76

GST (18%): ₹ 5,713.697

Total Price: ₹ 37,456.457

Antigen

Phospho-NPM1 (Ser4)

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P06748

Gene Symbols

NPM1

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Ser4 of human phospho-NPM.

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG κ

Applications

Flow Cytometry, Western Blot

Clone

NPMS4-A1

Conjugate

Unconjugated

Gene

NPM1

Gene Alias

B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg

Host Species

Rabbit

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

4869

Content And Storage

-20°C

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA542483

--

Img

Thermo Scientific

PIMA536981

--

Img

Thermo Scientific

PIMA536935

--

Img

Thermo Scientific

PIMA536997

--

Img

Thermo Scientific

PIMA537903

--

Img

Thermo Scientific

PIMA537898

--

Img

Thermo Scientific

PIMA542725

--

Img

Thermo Scientific

PIMA537900

--

Description

  • NPM1 (Nucleophosmin 1, B23, nutramin, NO38) is a ubiquitously expressed phosphoprotein involved in ribosome assembly/transport, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication, and regulation of p53
  • NPM1 continuously shuttles between the nucleus, cytoplasm, nucleolus and chaperoning core histones from the nucleus to the cytoplasm
  • NPM1 has been shown to bind nucleic acid, prevent protein aggregation via its chaperon activities, protect enzymes during thermal denaturation, and facilitate renaturation of chemically denatured proteins
  • In its cellular structure role, there is evidence suggesting NPM1 is associated with the centrosome, and is the substrate of CDK2/cyclin E during duplication of centrosomes (cellular division)
  • Due to the NPM1 gene interaction with several tumor-associated chromosome translocations, NPM1 is thought to be a portion of several fusion proteins: NPM-ALK, NPM-RAR, and NPM-MLF1
  • While it is not thought to be part of the transforming potential of these fusion proteins, NPM1 is believed to act as the interface for oligomerization and oncogenic conversion of these tumor promoting fusion proteins
  • Further, NPM1 is also known to sequester the tumor suppressor RF in the nucleolus, protecting it from degradation until it is necessary
  • Dysfunction of the NPM1 protein is associated with diseases such as acute myeloid leukemia and lymphomatoid papulosis.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA536893

--


Antigen:
Phospho-NPM1 (Ser4)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P06748

Gene Symbols:
NPM1

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser4 of human phospho-NPM.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry, Western Blot

Clone:
NPMS4-A1

Conjugate:
Unconjugated

Gene:
NPM1

Gene Alias:
B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
4869

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA536897

--


Antigen:
Phospho-ERK1/ERK2 (Thr202, Tyr204)

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P27361, P28482, P63085, Q63844

Gene Symbols:
MAPK1, MAPK3

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Thr202/Tyr204 of human phospho Erk1/2.

Quantity:
10 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry

Clone:
ERK12T202Y204-A11

Conjugate:
FITC

Gene:
MAPK1

Gene Alias:
12559; 9030612K14Rik; AA407128; AU018647; BcDNA:RE08694; C78273; CG12559; CG12559-PA; CG12559-PC; CG12559-PD; CG12559-PE; CG12559-PG; CG12559-PH; CG12559-PI; CG18732; CT34260; CT39192; DERK; D-ERK; DERK-A; Diphospho-ERK; dm-dpERK; Dmel\CG12559; Dmel_CG12559; DmErk; DmERKA; DmERK-A; DmMAPK; dpERK; dp-ERK; dpERK1; dpMAPK; drosophila ERK; Dsor2; E(sina)7; EC2-1; EK2-1; enhancer of seven in absentia 7; ERK; Erk MAP kinase; Erk/Map kinase; ERK/rolled; Erk1; Erk-1; erk1 erk2; Erk1/2; ERK1b; ERK2; ERK-2; ERKA; ERK-A; ERT1; ERT2; Esrk1; extracellular signal-regulated kinase; extracellular signal-regulated kinase (ERK2); extracellular signal-regulated kinase 1; Extracellular signal-regulated kinase 2; extracellular signal-regulated kinase A; extracellular signal-regulated kinase-1; extracellular signal-regulated kinase-2; extracellular signal-related kinase 1; Extracellular-regulated kinase A; extracellular-signal-regulated kinase 2; Extracellular-signal-related kinase A; EY2-2; fi06b09; GroupI

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
26413, 26417, 5594, 5595

Content And Storage:
4° C, store in dark

Form:
Liquid

Img

Thermo Scientific

PIMA536898

--


Antigen:
Phospho-ERK1/ERK2 (Thr202, Tyr204)

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P27361, P28482, P63085, Q63844

Gene Symbols:
MAPK1, MAPK3

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Thr202/Tyr204 of human phospho Erk1/2.

Quantity:
10 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry

Clone:
ERK12T202Y204-A11

Conjugate:
APC

Gene:
MAPK3

Gene Alias:
12559; 9030612K14Rik; AA407128; AU018647; BcDNA:RE08694; C78273; CG12559; CG12559-PA; CG12559-PC; CG12559-PD; CG12559-PE; CG12559-PG; CG12559-PH; CG12559-PI; CG18732; CT34260; CT39192; DERK; D-ERK; DERK-A; Diphospho-ERK; dm-dpERK; Dmel\CG12559; Dmel_CG12559; DmErk; DmERKA; DmERK-A; DmMAPK; dpERK; dp-ERK; dpERK1; dpMAPK; drosophila ERK; Dsor2; E(sina)7; EC2-1; EK2-1; enhancer of seven in absentia 7; ERK; Erk MAP kinase; Erk/Map kinase; ERK/rolled; Erk1; Erk-1; erk1 erk2; Erk1/2; ERK1b; ERK2; ERK-2; ERKA; ERK-A; ERT1; ERT2; Esrk1; extracellular signal-regulated kinase; extracellular signal-regulated kinase (ERK2); extracellular signal-regulated kinase 1; Extracellular signal-regulated kinase 2; extracellular signal-regulated kinase A; extracellular signal-regulated kinase-1; extracellular signal-regulated kinase-2; extracellular signal-related kinase 1; Extracellular-regulated kinase A; extracellular-signal-regulated kinase 2; Extracellular-signal-related kinase A; EY2-2; fi06b09; GroupI

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
26413, 26417, 5594, 5595

Content And Storage:
4° C

Form:
Liquid

Img

Fischer Scientific

PIMA536900

--


Antigen:
Phospho-Stat3 (Tyr705)

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
P40763, P42227

Gene Symbols:
STAT3

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr705 of human phospho Stat3.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry

Clone:
Stat3Y705-B12

Conjugate:
PE

Gene:
STAT3

Gene Alias:
1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
20848, 6774

Content And Storage:
4° C

Form:
Liquid