PIMA537000

Phospho-SLP76 (Tyr128) Recombinant Rabbit Monoclonal Antibody (SLP76Y128-3F8), APC, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA537000-Each-of-1 In Stock ₹ 47,870.82

PIMA537000 - Each of 1

₹ 47,870.82

In Stock

Quantity

1

Base Price: ₹ 47,870.82

GST (18%): ₹ 8,616.748

Total Price: ₹ 56,487.568

Antigen

Phospho-SLP76 (Tyr128)

Classification

Monoclonal

Conjugate

APC

Gene

LCP2

Gene Alias

76 kDa tyrosine phosphoprotein; AI323664; BB161688; Lcp2; Lymphocyte cytosolic protein 2; lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa); lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); SH2 domain-containing leukocyte protein of 76 kDa; SH2 domain-containing leukocyte protein of 76kD; SLP76; SLP-76; SLP-76 tyrosine phosphoprotein; twm

Host Species

Rabbit

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

16822, 3937

Content And Storage

4° C

Form

Liquid

Applications

Flow Cytometry

Clone

SLP76Y128-3F8

Formulation

PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.

Q13094, Q60787

Gene Symbols

LCP2

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Tyr128 of human phospho SLP-76.

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG κ

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Description

  • SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat
  • The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice
  • The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains
  • The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation
  • SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain
  • A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein
  • Studies using SLP-76 deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function.

Compare Similar Items

Show Difference

Img

Fischer Scientific

PIMA537000

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Antigen:
Phospho-SLP76 (Tyr128)

Classification:
Monoclonal

Conjugate:
APC

Gene:
LCP2

Gene Alias:
76 kDa tyrosine phosphoprotein; AI323664; BB161688; Lcp2; Lymphocyte cytosolic protein 2; lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa); lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); SH2 domain-containing leukocyte protein of 76 kDa; SH2 domain-containing leukocyte protein of 76kD; SLP76; SLP-76; SLP-76 tyrosine phosphoprotein; twm

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
16822, 3937

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry

Clone:
SLP76Y128-3F8

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
Q13094, Q60787

Gene Symbols:
LCP2

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr128 of human phospho SLP-76.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Img

Thermo Scientific

PIMA537001

--


Antigen:
Phospho-Chk1 (Ser317)

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
Chek1

Gene Alias:
C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
1111, 12649

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry

Clone:
Chk1S317-F10

Formulation:
PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O14757, O35280

Gene Symbols:
Chek1

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser317 of human phospho Chk1.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Img

Fischer Scientific

PIMA537003

--


Antigen:
Phospho-Chk1 (Ser317)

Classification:
Monoclonal

Conjugate:
FITC

Gene:
Chek1

Gene Alias:
C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
1111, 12649

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
Flow Cytometry

Clone:
chk1S317-F10

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
O14757, O35280

Gene Symbols:
Chek1

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser317 of human phospho Chk1.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Img

Fischer Scientific

PIMA537004

--


Antigen:
Phospho-Chk1 (Ser317)

Classification:
Monoclonal

Conjugate:
APC

Gene:
Chek1

Gene Alias:
C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
1111, 12649

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry

Clone:
Chk1S317-F10

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
O14757, O35280

Gene Symbols:
Chek1

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser317 of human phospho Chk1.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ