PIMA537014

Phospho-MSK1 (Thr581) Recombinant Rabbit Monoclonal Antibody (MSK1T581-A5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA537014-Each-of-1 In Stock ₹ 31,742.76

PIMA537014 - Each of 1

₹ 31,742.76

In Stock

Quantity

1

Base Price: ₹ 31,742.76

GST (18%): ₹ 5,713.697

Total Price: ₹ 37,456.457

Antigen

Phospho-MSK1 (Thr581)

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O75582, Q8C050

Gene Symbols

Rps6ka5

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Thr581 of human phospho MSK1.

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG κ

Applications

Flow Cytometry, Western Blot

Clone

MSK1T581-A5

Conjugate

Unconjugated

Gene

Rps6ka5

Gene Alias

3110005L17Rik; 6330404E13Rik; 90 kDa ribosomal protein S6 kinase 5; AI854034; kinase MSK1; KS6A5; mitogen and stress-activated protein kinase 1; Msk1; MSPK1; Nuclear mitogen- and stress-activated protein kinase 1; ribosomal protein S6 kinase A5; ribosomal protein S6 kinase alpha-5; ribosomal protein S6 kinase, 90kDa, polypeptide 5; ribosomal protein S6 kinase, polypeptide 5; RLPK; RLSK; Rps6ka5; RSKL; RSK-like protein kinase; S6K-alpha-5

Host Species

Rabbit

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

314384, 73086, 9252

Content And Storage

-20°C

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • RPS6KA5 (MSK1) is a serine/threonine protein kinase that is essential for the regulation of various cellular processes
  • RPS6KA5 is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes
  • Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin
  • Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates in the cytoplasm with the glucocorticoid receptor NR3C1 and contributes to RELA inhibition and repression of inflammatory gene expression
  • In skeletal myoblasts is required for phosphorylation of RELA at 'Ser-276' during oxidative stress
  • In erythropoietin-stimulated cells, is necessary for the 'Ser-727' phosphorylation of STAT3 and regulation of its transcriptional potential.

Compare Similar Items

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Img

Thermo Scientific

PIMA537014

--


Antigen:
Phospho-MSK1 (Thr581)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O75582, Q8C050

Gene Symbols:
Rps6ka5

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Thr581 of human phospho MSK1.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry, Western Blot

Clone:
MSK1T581-A5

Conjugate:
Unconjugated

Gene:
Rps6ka5

Gene Alias:
3110005L17Rik; 6330404E13Rik; 90 kDa ribosomal protein S6 kinase 5; AI854034; kinase MSK1; KS6A5; mitogen and stress-activated protein kinase 1; Msk1; MSPK1; Nuclear mitogen- and stress-activated protein kinase 1; ribosomal protein S6 kinase A5; ribosomal protein S6 kinase alpha-5; ribosomal protein S6 kinase, 90kDa, polypeptide 5; ribosomal protein S6 kinase, polypeptide 5; RLPK; RLSK; Rps6ka5; RSKL; RSK-like protein kinase; S6K-alpha-5

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
314384, 73086, 9252

Content And Storage:
-20°C

Form:
Liquid

Img

Fischer Scientific

PIMA537015

--


Antigen:
Phospho-MSK1 (Thr581)

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
O75582, Q8C050

Gene Symbols:
Rps6ka5

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Thr581 of human phospho MSK1.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry

Clone:
MSK1T581-A5

Conjugate:
APC

Gene:
Rps6ka5

Gene Alias:
3110005L17Rik; 6330404E13Rik; 90 kDa ribosomal protein S6 kinase 5; AI854034; kinase MSK1; KS6A5; mitogen and stress-activated protein kinase 1; Msk1; MSPK1; Nuclear mitogen- and stress-activated protein kinase 1; ribosomal protein S6 kinase A5; ribosomal protein S6 kinase alpha-5; ribosomal protein S6 kinase, 90kDa, polypeptide 5; ribosomal protein S6 kinase, polypeptide 5; RLPK; RLSK; Rps6ka5; RSKL; RSK-like protein kinase; S6K-alpha-5

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
314384, 73086, 9252

Content And Storage:
4° C

Form:
Liquid

Img

Fischer Scientific

PIMA537017

--


Antigen:
Phospho-KSR1 (Ser392)

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
Q61097, Q8IVT5

Gene Symbols:
KSR1

Immunogen:
A synthetic phosphor-peptide corresponding to residues surrounding Ser392 of human phospho KSR1.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry

Clone:
KSR1S392-3A4

Conjugate:
PE

Gene:
KSR1

Gene Alias:
AW492498; B-KSR1; CAP kinase; D11Bhm183e; D11Bhm184e; hb; HB protein; kinase KSR1; Kinase suppressor of Ras 1; Ksr; KSR1; mKSR1; OTTHUMP00000162931; protein Hb; RSU2

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
16706, 8844

Content And Storage:
4° C

Form:
Liquid

Img

Fischer Scientific

PIMA537018

--


Antigen:
Phospho-KSR1 (Ser392)

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
Q61097, Q8IVT5

Gene Symbols:
KSR1

Immunogen:
A synthetic phospho-peptide corresponding to residue surrounding Ser392 of human phospho KSR1.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry

Clone:
KSR1S392-3A4

Conjugate:
FITC

Gene:
KSR1

Gene Alias:
AW492498; B-KSR1; CAP kinase; D11Bhm183e; D11Bhm184e; hb; HB protein; kinase KSR1; Kinase suppressor of Ras 1; Ksr; KSR1; mKSR1; OTTHUMP00000162931; protein Hb; RSU2

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
16706, 8844

Content And Storage:
4° C, store in dark

Form:
Liquid