PIMA537024
Phospho-Histone H2A.X (Ser139) Recombinant Rabbit Monoclonal Antibody (HisH2AXS139-1B3), PE, Invitrogen™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA537024-Each-of-1 | In Stock | ₹ 46,501.86 |
PIMA537024 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,501.86
GST (18%): ₹ 8,370.335
Total Price: ₹ 54,872.195
Antigen
Phospho-Histone H2A.X (Ser139)
Classification
Monoclonal
Conjugate
PE
Gene
H2AX
Gene Alias
AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2A.X; H2A.X variant histone; H2A/X; h2afx; H2ax; H2AX histone; Hist5-2ax; histone 5 protein 2ax; histone H2A.x; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329
Host Species
Rabbit
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
15270, 3014
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry
Clone
HisH2AXS139-1B3
Formulation
PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.
P16104, P27661
Gene Symbols
H2AX
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser139 of human phospho histone H2A.X.
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG κ
Related Products
Description
- Description Histone H2A.X (H2AX) is a member of the histone H2A family which is one of the four core histones making up the nucleosome core particle
- In eukaryotes, DNA double strand breaks (DSBs) have been shown to trigger the phosphorylation of serine 139 at the carboxy terminus of histone H2AX resulting in gamma-H2AX
- The phosphorylation of H2AX can be detected by Western blotting or immunofluorescence, revealing the frequency of DSBs
- The phosphatidylinositol 3-kinases have been implicated in H2AX phosphorylation, but it is unclear if ATM is the primary H2AX kinase or if other members of the family such as DNA-PK and ATR contribute in a similar manner
- Structurally, H2A.x contains 143 amino acid residues
- Histone H2A.X is considered a basal histone, being synthesized in G1 as well as in S-phase, and its mRNA contains polyA addition motifs and a polyA tail along with the conserved stem-loop and U7 binding sequences involved in the processing and stability of replication type histone mRNAs
- There are two forms of Histone H2A.X mRNA, one about 1600 bases long and contains polyA; the other about 575 bases long, lacking polyA
- The short form behaves as a replication type histone mRNA, while the longer behaves as a basal type histone mRNA
- Histone H2A.X maps to the 11q23.2-q23.3 region of the human chromosome
- Histone H2A.x contributes to histone-formation and therefore the structure of DNA
- Histone H2A variant H2A.x specifically regulates the interaction of MDC1 (mediator of DNA damage checkpoint protein 1), a DNA repair protein to the sites of DNA damage.
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Antigen: Phospho-Histone H2A.X (Ser139)
Classification: Monoclonal
Conjugate: PE
Gene: H2AX
Gene Alias: AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2A.X; H2A.X variant histone; H2A/X; h2afx; H2ax; H2AX histone; Hist5-2ax; histone 5 protein 2ax; histone H2A.x; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 15270, 3014
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: HisH2AXS139-1B3
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.: P16104, P27661
Gene Symbols: H2AX
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser139 of human phospho histone H2A.X.
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG κ
Antigen:
Phospho-Histone H2A.X (Ser139)
Classification:
Monoclonal
Conjugate:
PE
Gene:
H2AX
Gene Alias:
AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2A.X; H2A.X variant histone; H2A/X; h2afx; H2ax; H2AX histone; Hist5-2ax; histone 5 protein 2ax; histone H2A.x; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
15270, 3014
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
HisH2AXS139-1B3
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.:
P16104, P27661
Gene Symbols:
H2AX
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser139 of human phospho histone H2A.X.
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG κ
Antigen: Phospho-PLCg1 (Tyr783)
Classification: Monoclonal
Conjugate: Unconjugated
Gene: PLCG1
Gene Alias: 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; AI894140; Cded; cell differentiation and embryonic development; EC 3.1.4.11; inositoltrisphosphohydrolase; monophosphatidylinositol phosphodiesterase; NCKAP3; OTTHUMP00000178982; phosphatidylinositol phospholipase C; phosphoinositidase C; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-1; phospholipase C gamma 1; phospholipase C, gamma 1; phospholipase C, gamma 1 (formerly subtype 148); phospholipase C-1; phospholipase C-148; Phospholipase C2; phospholipase C-gamma-1; Phospholipase C-II; PLC gamma1; PLC1; Plc-1; PLC148; PLC-148; PLC2I; Plcg1; Plcg-1; PLCgamma1; Plc-gamma1; PLC-gamma-1; PLC-II; PPLCA; triphosphoinositide phosphodiesterase
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 18803, 5335
Content And Storage: -20°C
Form: Liquid
Applications: Flow Cytometry
Clone: PLCG1Y783-C4
Formulation: PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P19174, Q62077
Gene Symbols: PLCG1
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr783 of human phospho PLCg1.
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG κ
Antigen:
Phospho-PLCg1 (Tyr783)
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
PLCG1
Gene Alias:
1-phosphatidyl-D-myo-inositol-4,5-bisphosphate; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; AI894140; Cded; cell differentiation and embryonic development; EC 3.1.4.11; inositoltrisphosphohydrolase; monophosphatidylinositol phosphodiesterase; NCKAP3; OTTHUMP00000178982; phosphatidylinositol phospholipase C; phosphoinositidase C; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-1; phospholipase C gamma 1; phospholipase C, gamma 1; phospholipase C, gamma 1 (formerly subtype 148); phospholipase C-1; phospholipase C-148; Phospholipase C2; phospholipase C-gamma-1; Phospholipase C-II; PLC gamma1; PLC1; Plc-1; PLC148; PLC-148; PLC2I; Plcg1; Plcg-1; PLCgamma1; Plc-gamma1; PLC-gamma-1; PLC-II; PPLCA; triphosphoinositide phosphodiesterase
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
18803, 5335
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
PLCG1Y783-C4
Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P19174, Q62077
Gene Symbols:
PLCG1
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr783 of human phospho PLCg1.
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG κ
Antigen: Phospho-PLCg1 (Tyr783)
Classification: Monoclonal
Conjugate: PE
Gene: PLCG1
Gene Alias: 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; AI894140; Cded; cell differentiation and embryonic development; EC 3.1.4.11; inositoltrisphosphohydrolase; monophosphatidylinositol phosphodiesterase; NCKAP3; OTTHUMP00000178982; phosphatidylinositol phospholipase C; phosphoinositidase C; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-1; phospholipase C gamma 1; phospholipase C, gamma 1; phospholipase C, gamma 1 (formerly subtype 148); phospholipase C-1; phospholipase C-148; Phospholipase C2; phospholipase C-gamma-1; Phospholipase C-II; PLC gamma1; PLC1; Plc-1; PLC148; PLC-148; PLC2I; Plcg1; Plcg-1; PLCgamma1; Plc-gamma1; PLC-gamma-1; PLC-II; PPLCA; triphosphoinositide phosphodiesterase
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 18803, 5335
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: PLCG1Y783-C4
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.: P19174, Q62077
Gene Symbols: PLCG1
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr783 of human phospho PLCgamma1.
Quantity: 10 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG κ
Antigen:
Phospho-PLCg1 (Tyr783)
Classification:
Monoclonal
Conjugate:
PE
Gene:
PLCG1
Gene Alias:
1-phosphatidyl-D-myo-inositol-4,5-bisphosphate; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; AI894140; Cded; cell differentiation and embryonic development; EC 3.1.4.11; inositoltrisphosphohydrolase; monophosphatidylinositol phosphodiesterase; NCKAP3; OTTHUMP00000178982; phosphatidylinositol phospholipase C; phosphoinositidase C; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-1; phospholipase C gamma 1; phospholipase C, gamma 1; phospholipase C, gamma 1 (formerly subtype 148); phospholipase C-1; phospholipase C-148; Phospholipase C2; phospholipase C-gamma-1; Phospholipase C-II; PLC gamma1; PLC1; Plc-1; PLC148; PLC-148; PLC2I; Plcg1; Plcg-1; PLCgamma1; Plc-gamma1; PLC-gamma-1; PLC-II; PPLCA; triphosphoinositide phosphodiesterase
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
18803, 5335
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
PLCG1Y783-C4
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.:
P19174, Q62077
Gene Symbols:
PLCG1
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr783 of human phospho PLCgamma1.
Quantity:
10 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG κ
Antigen: Phospho-RelB (Ser552)
Classification: Monoclonal
Conjugate: PE
Gene: RELB
Gene Alias: avian reticuloendotheliosis viral (v-rel) oncogene related B; IREL; I-REL; OTTHUMP00000221313; rel b; RELB; REL-B; RELB proto-oncogene, NF-kB subunit; shep; transcription factor RelB; v-rel avian reticuloendotheliosis viral oncogene homolog B; v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3); v-rel reticuloen; v-rel reticuloendotheliosis viral oncogene homolog B; v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 19698, 5971
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: RelBS552-A7
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.: Q01201, Q04863
Gene Symbols: RELB
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser552 of human phospho RelB.
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG κ
Antigen:
Phospho-RelB (Ser552)
Classification:
Monoclonal
Conjugate:
PE
Gene:
RELB
Gene Alias:
avian reticuloendotheliosis viral (v-rel) oncogene related B; IREL; I-REL; OTTHUMP00000221313; rel b; RELB; REL-B; RELB proto-oncogene, NF-kB subunit; shep; transcription factor RelB; v-rel avian reticuloendotheliosis viral oncogene homolog B; v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3); v-rel reticuloen; v-rel reticuloendotheliosis viral oncogene homolog B; v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
19698, 5971
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
RelBS552-A7
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.:
Q01201, Q04863
Gene Symbols:
RELB
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser552 of human phospho RelB.
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG κ