PIMA537051
Phospho-PTEN (Ser380) Recombinant Rabbit Monoclonal Antibody (PTENS380-NA9), PE, Invitrogen™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA537051-Each-of-1 | In Stock | ₹ 46,501.86 |
PIMA537051 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,501.86
GST (18%): ₹ 8,370.335
Total Price: ₹ 54,872.195
Antigen
Phospho-PTEN (Ser380)
Classification
Monoclonal
Conjugate
PE
Gene
PTEN
Gene Alias
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Host Species
Rabbit
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
19211, 5728
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry
Clone
PTENS380-NA9
Formulation
PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.
O08586, P60484
Gene Symbols
PTEN
Immunogen
A synthetic phospho peptide corresponding to residues surrounding Ser380 of human phospho PTEN.
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG κ
Description
- PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency
- The PTEN gene is a phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase
- It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases
- Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates
- PTEN negatively regulates intracellular levels of phosphatidylinositol-3, 4, 5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway
- PTEN plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation
- Also, PTEN may be a negative regulator of insulin signaling and glucose metabolism in adipose tissue
- The nuclear monoubiquitinated form possesses greater apoptotic potential, whereas the cytoplasmic nonubiquitinated form of PTEN induces less tumor suppressive ability.
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Antigen: Phospho-PTEN (Ser380)
Classification: Monoclonal
Conjugate: PE
Gene: PTEN
Gene Alias: 10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 19211, 5728
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: PTENS380-NA9
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.: O08586, P60484
Gene Symbols: PTEN
Immunogen: A synthetic phospho peptide corresponding to residues surrounding Ser380 of human phospho PTEN.
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG κ
Antigen:
Phospho-PTEN (Ser380)
Classification:
Monoclonal
Conjugate:
PE
Gene:
PTEN
Gene Alias:
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
19211, 5728
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
PTENS380-NA9
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.:
O08586, P60484
Gene Symbols:
PTEN
Immunogen:
A synthetic phospho peptide corresponding to residues surrounding Ser380 of human phospho PTEN.
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG κ
Antigen: Phospho-PTEN (Ser380)
Classification: Monoclonal
Conjugate: FITC
Gene: PTEN
Gene Alias: 10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 19211, 5728
Content And Storage: 4° C, store in dark
Form: Liquid
Applications: Flow Cytometry
Clone: PTENS380-NA9
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.: O08586, P60484
Gene Symbols: PTEN
Immunogen: A synthetic phospho peptide corresponding to residues surrounding Ser380 of human phospho PTEN.
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG κ
Antigen:
Phospho-PTEN (Ser380)
Classification:
Monoclonal
Conjugate:
FITC
Gene:
PTEN
Gene Alias:
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
19211, 5728
Content And Storage:
4° C, store in dark
Form:
Liquid
Applications:
Flow Cytometry
Clone:
PTENS380-NA9
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.:
O08586, P60484
Gene Symbols:
PTEN
Immunogen:
A synthetic phospho peptide corresponding to residues surrounding Ser380 of human phospho PTEN.
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG κ
Antigen: Phospho-PTEN (Ser380)
Classification: Monoclonal
Conjugate: APC
Gene: PTEN
Gene Alias: 10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 19211, 5728
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: PTENS380-NA9
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.: O08586, P60484
Gene Symbols: PTEN
Immunogen: A synthetic phospho peptide corresponding to residues surrounding Ser380 of human phospho PTEN.
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG κ
Antigen:
Phospho-PTEN (Ser380)
Classification:
Monoclonal
Conjugate:
APC
Gene:
PTEN
Gene Alias:
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
19211, 5728
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
PTENS380-NA9
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.:
O08586, P60484
Gene Symbols:
PTEN
Immunogen:
A synthetic phospho peptide corresponding to residues surrounding Ser380 of human phospho PTEN.
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG κ
Antigen: Phospho-MEK3/MEK6 (Ser189, Ser207)
Classification: Monoclonal
Conjugate: Unconjugated
Gene: MAP2K3
Gene Alias: AW212142; dual specificity mitogen-activated protein kinase kinase 3; Dual specificity mitogen-activated protein kinase kinase 6; MAP kinase kinase 3; MAP kinase kinase 6; Map2k3; Map2k6; MAPK/ERK kinase 3; MAPK/ERK kinase 6; MAPKK 3; MAPKK 6; MAPKK3; MAPKK6; MEK 3; MEK 6; MEK3; MEK6; mitogen activated protein kinase kinase 3; mitogen activated protein kinase kinase 6; mitogen-activated protein kinase kinase 3; mitogen-activated protein kinase kinase 6; MKK3; MKK6; mMKK3b; OTTHUMP00000166044; Prkmk3; Prkmk6; protein kinase, mitogen activated, kinase 6; protein kinase, mitogen-activated, kinase 3; protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6); SAPK kinase 2; SAPK kinase 3; SAPKK2; SAPKK-2; SAPKK3; SAPKK-3; SKK2; SKK3; Stress-activated protein kinase kinase 2; stress-activated protein kinase kinase 3
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 26397, 26399, 5606, 5608
Content And Storage: -20°C
Form: Liquid
Applications: Flow Cytometry, Western Blot
Clone: MKK3S189MKK6S207-D3
Formulation: PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O09110, P46734, P52564, P70236
Gene Symbols: MAP2K3, MAP2K6
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser189 of human phospho MKK3 and Ser207 of human phospho MKK6.
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG κ
Antigen:
Phospho-MEK3/MEK6 (Ser189, Ser207)
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
MAP2K3
Gene Alias:
AW212142; dual specificity mitogen-activated protein kinase kinase 3; Dual specificity mitogen-activated protein kinase kinase 6; MAP kinase kinase 3; MAP kinase kinase 6; Map2k3; Map2k6; MAPK/ERK kinase 3; MAPK/ERK kinase 6; MAPKK 3; MAPKK 6; MAPKK3; MAPKK6; MEK 3; MEK 6; MEK3; MEK6; mitogen activated protein kinase kinase 3; mitogen activated protein kinase kinase 6; mitogen-activated protein kinase kinase 3; mitogen-activated protein kinase kinase 6; MKK3; MKK6; mMKK3b; OTTHUMP00000166044; Prkmk3; Prkmk6; protein kinase, mitogen activated, kinase 6; protein kinase, mitogen-activated, kinase 3; protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6); SAPK kinase 2; SAPK kinase 3; SAPKK2; SAPKK-2; SAPKK3; SAPKK-3; SKK2; SKK3; Stress-activated protein kinase kinase 2; stress-activated protein kinase kinase 3
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
26397, 26399, 5606, 5608
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry, Western Blot
Clone:
MKK3S189MKK6S207-D3
Formulation:
PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O09110, P46734, P52564, P70236
Gene Symbols:
MAP2K3, MAP2K6
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser189 of human phospho MKK3 and Ser207 of human phospho MKK6.
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG κ