PIMA537090

Phospho-PDPK1 (Ser241) Recombinant Rabbit Monoclonal Antibody (PDK1S241-F7), FITC, Invitrogen™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA537090-Each-of-1 In Stock ₹ 46,501.86

PIMA537090 - Each of 1

₹ 46,501.86

In Stock

Quantity

1

Base Price: ₹ 46,501.86

GST (18%): ₹ 8,370.335

Total Price: ₹ 54,872.195

Antigen

Phospho-PDPK1 (Ser241)

Classification

Monoclonal

Conjugate

FITC

Gene

Pdpk1

Gene Alias

3-phosphoinositide dependent protein kinase 1; 3-phosphoinositide dependent protein kinase-1; 3-phosphoinositide-dependent protein kinase 1; 3-phosphoinositide-dependent protein kinase 2 pseudogene; HGNC:8809; hPDK1; isoenzyme 1; kinase isoenzyme 1; lipoamide; mPDK1; OTTHUMP00000174525; OTTHUMP00000205076; PDK1; PDPK1; PDPK2; PDPK2P; Pkb kinase; PkB kinase like gene 1; PkB-like 1; PRO0461; Protein kinase B kinase

Host Species

Rabbit

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

5170

Content And Storage

4° C, store in dark

Form

Liquid

Applications

Flow Cytometry

Clone

PDK1S241-F7

Formulation

PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.

O15530

Gene Symbols

Pdpk1

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Ser241 of human phospho PDPK1.

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG κ

Description

  • PDPK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases
  • PDPK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop
  • PDPK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate
  • Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase, and the stimulation of glycogen synthesis
  • Because of the role that PDPK1 plays in insulin-induced glycogen synthesis and PKC activation, it is a potentially important target for metabolic drug research.

Compare Similar Items

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Img

Fischer Scientific

PIMA537090

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Antigen:
Phospho-PDPK1 (Ser241)

Classification:
Monoclonal

Conjugate:
FITC

Gene:
Pdpk1

Gene Alias:
3-phosphoinositide dependent protein kinase 1; 3-phosphoinositide dependent protein kinase-1; 3-phosphoinositide-dependent protein kinase 1; 3-phosphoinositide-dependent protein kinase 2 pseudogene; HGNC:8809; hPDK1; isoenzyme 1; kinase isoenzyme 1; lipoamide; mPDK1; OTTHUMP00000174525; OTTHUMP00000205076; PDK1; PDPK1; PDPK2; PDPK2P; Pkb kinase; PkB kinase like gene 1; PkB-like 1; PRO0461; Protein kinase B kinase

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
5170

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
Flow Cytometry

Clone:
PDK1S241-F7

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
O15530

Gene Symbols:
Pdpk1

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser241 of human phospho PDPK1.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG κ

Img

Thermo Scientific

PIMA537092

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Antigen:
Phospho-Lck (Tyr505)

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
LCK

Gene Alias:
EC 2.7.10.2; Hck-3; IMD22; kinase Lck; Lck; LCK proto-oncogene, Src family tyrosine kinase; Lck1; Lcktkr; leukocyte C-terminal Src kinase; LSK; Lskt; Lsk-t; Lymphocyte cell-specific protein-tyrosine kinase; lymphocyte protein tyrosine kinase; lymphocyte-specific protein tyrosine kinase; OTTHUMP00000008640; OTTHUMP00000008740; OTTHUMP00000008741; p56(LSTRA) protein-tyrosine kinase; p56<lck>; p56lck; p56-LCK; pp58lck; Protein YT16; Proto-oncogene Lck; Proto-oncogene tyrosine-protein kinase LCK; RP4-675E8.4; t cell-specific protein-tyrosine kinase; T-lymphocyte specific protein tyrosine kinase p56lck; tyr; tyrosine-protein kinase Lck; YT16

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
3932

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Clone:
LckY505-A3

Formulation:
PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P06239

Gene Symbols:
LCK

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr505 of human phospho Lck.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG κ

Img

Fischer Scientific

PIMA537093

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Antigen:
Phospho-Lck (Tyr505)

Classification:
Monoclonal

Conjugate:
PE

Gene:
LCK

Gene Alias:
EC 2.7.10.2; Hck-3; IMD22; kinase Lck; Lck; LCK proto-oncogene, Src family tyrosine kinase; Lck1; Lcktkr; leukocyte C-terminal Src kinase; LSK; Lskt; Lsk-t; Lymphocyte cell-specific protein-tyrosine kinase; lymphocyte protein tyrosine kinase; lymphocyte-specific protein tyrosine kinase; OTTHUMP00000008640; OTTHUMP00000008740; OTTHUMP00000008741; p56(LSTRA) protein-tyrosine kinase; p56<lck>; p56lck; p56-LCK; pp58lck; Protein YT16; Proto-oncogene Lck; Proto-oncogene tyrosine-protein kinase LCK; RP4-675E8.4; t cell-specific protein-tyrosine kinase; T-lymphocyte specific protein tyrosine kinase p56lck; tyr; tyrosine-protein kinase Lck; YT16

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
3932

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry

Clone:
LckY505-A3

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
P06239

Gene Symbols:
LCK

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr505 of human phospho Lck.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG κ

Img

Fischer Scientific

PIMA537098

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Antigen:
Phospho-MEK1/MEK2 (Ser217, Ser221)

Classification:
Monoclonal

Conjugate:
FITC

Gene:
MAP2K2

Gene Alias:
AA589381; CFC3; CFC4; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; Dual specificity mitogen-activated protein kinase kinase 2; EC 2.7.12.2; ERK activator kinase 1; ERK activator kinase 2; hypothetical protein; hypothetical protein LOC406728; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase 2; MAP kinase/Erk kinase; MAP kinase/Erk kinase 1; Map2k1; Map2k2; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK 2; MAPKK1; MAPKK2; MEK 1; MEK 2; Mek1; MEK-1; Mek2; MEK-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen activated protein kinase kinase 2; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; mitogen-activated protein kinase kinase type 2; MK2; MKK1; MKK2; MP2K1; PRKMK1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen activated, kinase 2, p45; protein kinase, mitogen-activated, ki

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
5604, 5605

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MEK12S217S221-H2

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
P36507, Q02750

Gene Symbols:
MAP2K1, MAP2K2

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser217/221 of human phospho MEK1/2.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG κ