PIMA537199

Phospho-Jak2 (Tyr1007, Tyr1008) Recombinant Rabbit Monoclonal Antibody (JAK2Y10071008-PB6), APC, Invitrogen™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA537199-Each-of-1 In Stock ₹ 47,870.82

PIMA537199 - Each of 1

₹ 47,870.82

In Stock

Quantity

1

Base Price: ₹ 47,870.82

GST (18%): ₹ 8,616.748

Total Price: ₹ 56,487.568

Antigen

Phospho-Jak2 (Tyr1007, Tyr1008)

Classification

Monoclonal

Conjugate

APC

Gene

JAK2

Gene Alias

EC 2.7.10.2; Fd17; JAK 2; JAK2; JAK-2; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); JTK 10; JTK10; kinase Jak2; THCYT3; Tyrosine-protein kinase JAK2

Host Species

Rabbit

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

3717

Content And Storage

4° C

Form

Liquid

Applications

Flow Cytometry

Clone

JAK2Y10071008-PB6

Formulation

PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.

O60674

Gene Symbols

JAK2

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Tyr1007/Tyr1008 of human phospho Jak2.

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG κ

Description

  • Janus kinase 2 (JAK2) is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera
  • This kinase contains the catalytic domain (JH1) of JAK2
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex
  • Mutations affecting JAK2 can cause Budd-Chiari syndrome, Polycythemia vera, Thrombocythemia 3, myelofibrosis, or Acute myelogenous leukemia.

Compare Similar Items

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Img

Fischer Scientific

PIMA537199

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Antigen:
Phospho-Jak2 (Tyr1007, Tyr1008)

Classification:
Monoclonal

Conjugate:
APC

Gene:
JAK2

Gene Alias:
EC 2.7.10.2; Fd17; JAK 2; JAK2; JAK-2; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); JTK 10; JTK10; kinase Jak2; THCYT3; Tyrosine-protein kinase JAK2

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
3717

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry

Clone:
JAK2Y10071008-PB6

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
O60674

Gene Symbols:
JAK2

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr1007/Tyr1008 of human phospho Jak2.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG κ

Img

Fischer Scientific

PIMA537200

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Antigen:
Phospho-NFKB p65 (Ser468)

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
RELA

Gene Alias:
avian reticuloendotheliosis viral (v-rel) oncogene homolog A; EBP-1; I79_021812; MGC131774; NF KB; NFkappaB p65; nf-kappa-b p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NF-kappaB transcription factor p65 subunit; NFkB; NF-kB p65 subunit; nfkb rela; NFKB1; nfkb3; NFkB-p50; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit p65; nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; P65 transcription factor; putative transcription factor p65 homolog; REL A; rel1; rela; RELA proto-oncogene, NF-kB subunit; rela.L; rela-a; Transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; XELAEV_18022301mg; Xrel1; xrela

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
5970

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry

Clone:
NFKBp65S468-B9

Formulation:
PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q04206

Gene Symbols:
RELA

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser536 of human phospho-NFKB p65.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG κ

Img

Fischer Scientific

PIMA537202

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Antigen:
Phospho-Jak3 (Tyr980, Tyr981)

Classification:
Monoclonal

Conjugate:
FITC

Gene:
JAK3

Gene Alias:
Breast-JAK3; fae; JAK3; JAK-3; JAK3_HUMAN; JAK3B; JAKL; Janus kinase 3; Janus kinase 3 (a protein tyrosine kinase, leukocyte); Janus kinase 3 protein-tyrosine kinase; Janus kinase 3, protein-tyrosine kinase; L JAK; Leukocyte janus kinase; LJAK; L-JAK; RATJAK3; Tyrosine-protein kinase JAK3; wil

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
3718

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
Flow Cytometry

Clone:
JAK3Y980981-E10

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
P52333

Gene Symbols:
JAK3

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr980/981 of human Jak3.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG κ

Img

Fischer Scientific

PIMA537207

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Antigen:
SARS-CoV-2 Nucleocapsid

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
N

Gene Alias:
COVID19 Nucleocapsid, COVID-19 nucleocapsid, COVID19 Spike nucleocapsid, SARS-CoV-2 N

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
43740575

Content And Storage:
4° C

Form:
Liquid

Applications:
ELISA

Clone:
84C4A

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P0DTC9

Gene Symbols:
N

Immunogen:
SARS-CoV-2 nucleoprotein (NP) specific peptide.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Virus

Product Type:
Antibody

Isotype:
IgG κ