PIMA537257

Phospho-EGFR (Tyr1068) Recombinant Rabbit Monoclonal Antibody (EGFRY1068-E5), Invitrogen™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA537257-Each-of-1 In Stock ₹ 31,742.76

PIMA537257 - Each of 1

₹ 31,742.76

In Stock

Quantity

1

Base Price: ₹ 31,742.76

GST (18%): ₹ 5,713.697

Total Price: ₹ 37,456.457

Antigen

Phospho-EGFR (Tyr1068)

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P00533, Q01279

Gene Symbols

EGFR

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Tyr1068 of human phospho EGFR.

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG κ

Applications

Flow Cytometry

Clone

EGFRY1068-E5

Conjugate

Unconjugated

Gene

EGFR

Gene Alias

2.7.10.1; 9030024J15Rik; AI552599; avian erythroblastic leukemia viral (v-erbB) oncogene homolog; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; EC 2.7.10.1; egf receptor; Egfr; EGFR-related peptide; epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); ERBB; ERBB1; ErbB-1; erb-b2 receptor tyrosine kinase 1; Errb1; Errp; HER1; kinase EGFR; mENA; NISBD2; Oncogene ERBB; PIG61; Proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1; Urogastrone; wa2; wa-2; Wa5; waved 2

Host Species

Rabbit

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

13649, 1956, 24329

Content And Storage

-20°C

Form

Liquid

Description

  • EGFR, epidermal growth factor receptor, is a receptor tyrosine kinases that signals in response to various growth factors
  • Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics
  • EGFR is encoded by the EGFR gene located on chromosome 7 in humans
  • EGFR belongs to the HER/ERbB family of proteins that includes three other receptor tyrosine kinases, ERbB2, ERbB3, ERbB4
  • EGFR is a transmembrane receptor and binding of its cognate ligands such as EGF (Epidermal Growth Factor) and TGF alpha (Transforming Growth Factor alpha) to the extracellular domain leads to EGFR dimerization followed by autophosphorylation of the tyrosine residues in the cytoplasmic domain
  • Overexpression is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.

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Img

Fischer Scientific

PIMA537257

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Antigen:
Phospho-EGFR (Tyr1068)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P00533, Q01279

Gene Symbols:
EGFR

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr1068 of human phospho EGFR.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry

Clone:
EGFRY1068-E5

Conjugate:
Unconjugated

Gene:
EGFR

Gene Alias:
2.7.10.1; 9030024J15Rik; AI552599; avian erythroblastic leukemia viral (v-erbB) oncogene homolog; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; EC 2.7.10.1; egf receptor; Egfr; EGFR-related peptide; epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); ERBB; ERBB1; ErbB-1; erb-b2 receptor tyrosine kinase 1; Errb1; Errp; HER1; kinase EGFR; mENA; NISBD2; Oncogene ERBB; PIG61; Proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1; Urogastrone; wa2; wa-2; Wa5; waved 2

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
13649, 1956, 24329

Content And Storage:
-20°C

Form:
Liquid

Img

Fischer Scientific

PIMA537258

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Antigen:
Phospho-CrkL (Tyr207)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P46109, P47941

Gene Symbols:
CRKL

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr207 of human phospho CrkL.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry, Western Blot

Clone:
CrkLY207-G4

Conjugate:
Unconjugated

Gene:
CRKL

Gene Alias:
1110025F07Rik; AA589403; AI325100; CRK like proto-oncogene, adaptor protein; CRKL; crkl {ECO:0000312; crk-like protein; crk-like protein {ECO:0000250; Crkol; EMBL:AAH85865.1, ECO:0000312; OTTHUMP00000198539; RGD:1308531}; UniProtKB:P46109}; v-crk avian sarcoma virus CT10 oncogene homolog-like; v-crk sarcoma virus CT10 oncogene homolog (avian)-like; v-crk sarcoma virus CT10 oncogene homolog-like

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
12929, 1399

Content And Storage:
-20°C

Form:
Liquid

Img

Fischer Scientific

PIMA537260

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Antigen:
Phospho-CrkL (Tyr207)

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
P46109, P47941

Gene Symbols:
CRKL

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr207 of human phospho CrkL.

Quantity:
10 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry

Clone:
CrkLY207-G4

Conjugate:
APC

Gene:
CRKL

Gene Alias:
1110025F07Rik; AA589403; AI325100; CRK like proto-oncogene, adaptor protein; CRKL; crkl {ECO:0000312; crk-like protein; crk-like protein {ECO:0000250; Crkol; EMBL:AAH85865.1, ECO:0000312; OTTHUMP00000198539; RGD:1308531}; UniProtKB:P46109}; v-crk avian sarcoma virus CT10 oncogene homolog-like; v-crk sarcoma virus CT10 oncogene homolog (avian)-like; v-crk sarcoma virus CT10 oncogene homolog-like

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
12929, 1399

Content And Storage:
4° C

Form:
Liquid

Img

Fischer Scientific

PIMA537261

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Antigen:
Phospho-Ask1 (Ser83)

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
O35099, Q99683

Gene Symbols:
MAP3K5

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser83 of human phospho Ask1.

Quantity:
10 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry

Clone:
Ask1S83-G4

Conjugate:
PE

Gene:
MAP3K5

Gene Alias:
7420452D20Rik; apoptosis signal regulating kinase 1; apoptosis signal-regulating kinase 1; ASK; ASK 1; ASK1; ASK-1; EC 2.7.11.25; kinase ASK1; M3K5; MAP/ERK kinase kinase 5; Map3k5; MAPK/ERK kinase kinase 5; MAPKKK5; MEK kinase 5; MEKK 5; Mekk5; mitogen activated protein kinase kinase kinase 5; mitogen-activated protein kinase kinase kinase 5; RGD1306565; RP3-325F22.4

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
26408, 365057, 4217

Content And Storage:
4° C

Form:
Liquid