PIMA537326
Phospho-Chk1 (Ser317) Recombinant Rabbit Monoclonal Antibody (Chk1S317-G1), APC, Invitrogen™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA537326-Each-of-1 | In Stock | ₹ 18,994.32 |
PIMA537326 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 18,994.32
GST (18%): ₹ 3,418.978
Total Price: ₹ 22,413.298
Antigen
Phospho-Chk1 (Ser317)
Classification
Monoclonal
Conjugate
APC
Gene
Chek1
Gene Alias
C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W
Host Species
Rabbit
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
1111, 12649
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry
Clone
Chk1S317-G1
Formulation
PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.
O14757, O35280
Gene Symbols
Chek1
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser317 of human phospho Chk1.
Quantity
10 Tests
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG κ
Related Products
Description
- CHEK1 (CHK1) is a serine/threonine protein kinase involved in preventing replication when DNA integrity is compromised
- CHK1 is a key mediator in the DNA damage-induced checkpoint network
- CHK1 is an evolutionarily conserved protein kinase that functions to ensure genomic integrity upon genotoxic stress
- When the G2 or S checkpoint is abrogated by the inhibition of CHK1, p53-deficient cancer cells undergo mitotic catastrophe and eventually apoptosis, whereas normal cells are still arrested in the G1 phase
- Thus, CHK1 inhibitors can preferentially potentiate the efficacy of DNA damaging agents in cancer cells, and Chk1 is an attractive therapeutic target for cancer treatment, especially since approximately 50% of all human cancers are p53-deficient.
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Antigen: Phospho-Chk1 (Ser317)
Classification: Monoclonal
Conjugate: APC
Gene: Chek1
Gene Alias: C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 1111, 12649
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: Chk1S317-G1
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.: O14757, O35280
Gene Symbols: Chek1
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser317 of human phospho Chk1.
Quantity: 10 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG κ
Antigen:
Phospho-Chk1 (Ser317)
Classification:
Monoclonal
Conjugate:
APC
Gene:
Chek1
Gene Alias:
C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
1111, 12649
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
Chk1S317-G1
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.:
O14757, O35280
Gene Symbols:
Chek1
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser317 of human phospho Chk1.
Quantity:
10 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG κ
Antigen: Phospho-MEK1/MEK2 (Ser221)
Classification: Monoclonal
Conjugate: FITC
Gene: MAP2K2
Gene Alias: AA589381; CFC3; CFC4; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; Dual specificity mitogen-activated protein kinase kinase 2; EC 2.7.12.2; ERK activator kinase 1; ERK activator kinase 2; hypothetical protein; hypothetical protein LOC406728; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase 2; MAP kinase/Erk kinase; MAP kinase/Erk kinase 1; Map2k1; Map2k2; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK 2; MAPKK1; MAPKK2; MEK 1; MEK 2; Mek1; MEK-1; Mek2; MEK-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen activated protein kinase kinase 2; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; mitogen-activated protein kinase kinase type 2; MK2; MKK1; MKK2; MP2K1; PRKMK1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen activated, kinase 2, p45; protein kinase, mitogen-activated, ki
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 26395, 26396, 5604, 5605
Content And Storage: 4° C, store in dark
Form: Liquid
Applications: Flow Cytometry
Clone: MEK12S221-D3
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.: P31938, P36507, Q02750, Q63932
Gene Symbols: MAP2K1, MAP2K2
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser221 of human phospho MEK1/2.
Quantity: 10 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG κ
Antigen:
Phospho-MEK1/MEK2 (Ser221)
Classification:
Monoclonal
Conjugate:
FITC
Gene:
MAP2K2
Gene Alias:
AA589381; CFC3; CFC4; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; Dual specificity mitogen-activated protein kinase kinase 2; EC 2.7.12.2; ERK activator kinase 1; ERK activator kinase 2; hypothetical protein; hypothetical protein LOC406728; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase 2; MAP kinase/Erk kinase; MAP kinase/Erk kinase 1; Map2k1; Map2k2; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK 2; MAPKK1; MAPKK2; MEK 1; MEK 2; Mek1; MEK-1; Mek2; MEK-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen activated protein kinase kinase 2; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; mitogen-activated protein kinase kinase type 2; MK2; MKK1; MKK2; MP2K1; PRKMK1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen activated, kinase 2, p45; protein kinase, mitogen-activated, ki
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
26395, 26396, 5604, 5605
Content And Storage:
4° C, store in dark
Form:
Liquid
Applications:
Flow Cytometry
Clone:
MEK12S221-D3
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.:
P31938, P36507, Q02750, Q63932
Gene Symbols:
MAP2K1, MAP2K2
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser221 of human phospho MEK1/2.
Quantity:
10 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG κ
Antigen: Phospho-Akt1 (Thr308)
Classification: Monoclonal
Conjugate: Unconjugated
Gene: AKT1
Gene Alias: Akt; Akt kinase; AKT serine/threonine kinase 1; Akt/PKB; akt1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; CAKT; C-AKT; CG4006; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; dAkt; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; DAKT1; DAKT1/PKB; Dmel\CG4006; Dmel_CG4006; dPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; l(3)04226; l(3)89Bq; murine thymoma viral (v-akt) oncogene homolog 1; pAkt; P-AKT; PKB; PKB alpha; PKB beta; PKB gamma; PKB/AKT; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBG; PRKBA; protein kinase B; Protein kinase B alpha; protein kinase B-alpha; proto-oncogene c-Akt; RAC; rac protein kinase alpha; RAC protein kinase alpha RAC-PK alpha; RAC serine/threonine protein kinase; RAC serine/threonine-protein kinase; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RacPK; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; related to A and C kinases; related to PKA to PKC protein kinases; related to the A and C kinases; SD10374p; serine/threonine protein kinase
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 11651, 207
Content And Storage: -20°C
Form: Liquid
Applications: Flow Cytometry, Western Blot
Clone: AktT308-G12
Formulation: PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P31749, P31750
Gene Symbols: AKT1
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Thr308 of human phospho Akt1.
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG κ
Antigen:
Phospho-Akt1 (Thr308)
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
AKT1
Gene Alias:
Akt; Akt kinase; AKT serine/threonine kinase 1; Akt/PKB; akt1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; CAKT; C-AKT; CG4006; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; dAkt; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; DAKT1; DAKT1/PKB; Dmel\CG4006; Dmel_CG4006; dPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; l(3)04226; l(3)89Bq; murine thymoma viral (v-akt) oncogene homolog 1; pAkt; P-AKT; PKB; PKB alpha; PKB beta; PKB gamma; PKB/AKT; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBG; PRKBA; protein kinase B; Protein kinase B alpha; protein kinase B-alpha; proto-oncogene c-Akt; RAC; rac protein kinase alpha; RAC protein kinase alpha RAC-PK alpha; RAC serine/threonine protein kinase; RAC serine/threonine-protein kinase; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RacPK; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; related to A and C kinases; related to PKA to PKC protein kinases; related to the A and C kinases; SD10374p; serine/threonine protein kinase
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
11651, 207
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry, Western Blot
Clone:
AktT308-G12
Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P31749, P31750
Gene Symbols:
AKT1
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Thr308 of human phospho Akt1.
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG κ
Antigen: Phospho-BLNK (Tyr84)
Classification: Monoclonal
Conjugate: FITC
Gene: BLNK
Gene Alias: AGM4; B cell adaptor containing SH2 domain; B cell linker; B cell linker protein; BASH; bca; B-cell activation; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; B-cell linker; B-cell linker protein; Blnk; BLNK-S; Cytoplasmic adapter protein; LY57; Ly-57; lymphocyte antigen 57; Lyw-57; MGC111051; SLP65; Slp-65; Src homology [SH2] domain-containing leukocyte protein of 65 kD; Src homology 2 domain-containing leukocyte protein of 65 kDa
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 29760
Content And Storage: 4° C, store in dark
Form: Liquid
Applications: Flow Cytometry
Clone: BLNKY84-H4
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.: Q8WV28
Gene Symbols: BLNK
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr84 of human phospho BLNK.
Quantity: 10 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG κ
Antigen:
Phospho-BLNK (Tyr84)
Classification:
Monoclonal
Conjugate:
FITC
Gene:
BLNK
Gene Alias:
AGM4; B cell adaptor containing SH2 domain; B cell linker; B cell linker protein; BASH; bca; B-cell activation; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; B-cell linker; B-cell linker protein; Blnk; BLNK-S; Cytoplasmic adapter protein; LY57; Ly-57; lymphocyte antigen 57; Lyw-57; MGC111051; SLP65; Slp-65; Src homology [SH2] domain-containing leukocyte protein of 65 kD; Src homology 2 domain-containing leukocyte protein of 65 kDa
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
29760
Content And Storage:
4° C, store in dark
Form:
Liquid
Applications:
Flow Cytometry
Clone:
BLNKY84-H4
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.:
Q8WV28
Gene Symbols:
BLNK
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr84 of human phospho BLNK.
Quantity:
10 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG κ