PIMA537685

IRF3 Monoclonal Antibody (1522CT766.58.24), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA537685-Each-of-1 In Stock ₹ 44,619.54

PIMA537685 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

IRF3

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q14653

Gene Symbols

IRF3

Immunogen

IRF3 recombinant protein

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human, Non-human Primate

Product Type

Antibody

Isotype

IgG1 κ

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

1522CT766.58.24

Conjugate

Unconjugated

Gene

IRF3

Gene Alias

C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

3661

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • IFR3 (interferon regulatory factor 3) is a key transcriptional regulator of type I interferon (IFN)-dependent immune responses
  • It plays a critical role in the innate immune response against DNA and RNA viruses
  • IFR3 regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters
  • It acts as a more potent activator of the IFN-beta gene than the IFN-alpha gene and plays a critical role in both the early and late phases of the IFNA/B gene induction
  • IFR3 is found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA, or toll-like receptor signaling
  • It is phosphorylated by IKBKE and TBK1 kinases
  • This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes
  • Mutations in the gene can result in encephalopathy, acute, infection-induced, herpes-specific 7.

Compare Similar Items

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Img

Thermo Scientific

PIMA537685

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Antigen:
IRF3

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q14653

Gene Symbols:
IRF3

Immunogen:
IRF3 recombinant protein

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
1522CT766.58.24

Conjugate:
Unconjugated

Gene:
IRF3

Gene Alias:
C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3661

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA537686

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Antigen:
RAB11A

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P62491, P62492, P62494

Gene Symbols:
RAB11A

Immunogen:
purified recombinant protein of human RAB11A

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
1565CT164.36.80

Conjugate:
Unconjugated

Gene:
RAB11A

Gene Alias:
24KG; RAB 11A, member oncogene family; RAB11; rab-11; rab11 GTP-binding protein; Rab11a; RAB11a, member RAS oncogene family; ras-related protein Rab-11A; tubulovesicle-associated protein; YL8

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
53869, 81830, 8766

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA537687

--


Antigen:
GAPDH

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% ProClin 300

Gene Accession No.:
O14556, P04406

Gene Symbols:
GAPDH, GAPDHS

Immunogen:
recombinant protein of human GAPDH

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
1653CT401.3.33

Conjugate:
HRP

Gene:
GAPDHS

Gene Alias:
38 kDa BFA-dependent ADP-ribosylation substrate; aging-associated gene 9 protein; BARS-38; bb02e05; cb350; cb609; CDABP0047; EC 1.2.1.12; epididymis secretory protein Li 278; epididymis secretory sperm binding protein Li 162eP; fb71f08; fk58c09; G3PD; G3PDH; GAPD; GAPD2; gapdh; GAPDH2; GAPDH-2; GAPDHS; Gapds; Gapd-s; glceraldehyde-3-phosphate dehydrogenase; glyceraldehyde 3-phosphate dehydrogenase; glyceraldehyde 3-phosphate dehydrogenase, testis-specific; glyceraldehyde phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase (G3PDH); glyceraldehyde-3-phosphate dehydrogenase 2; glyceraldehyde-3-phosphate dehydrogenase GAPDH; glyceraldehyde-3-phosphate dehydrogenase like-17 protein; glyceraldehyde-3-phosphate dehydrogenase type 2; glyceraldehyde-3-phosphate dehydrogenase, spermatogenic; glyceraldehyde-3-phosphate dehydrogenase, testis-specific; glyceraldehyde-phosphate-dehydrogenase; glycerine aldehyde 3-phosphate dehydrogenase; HEL-S-162eP; HEL-S-278; HGNC:4141; HSD35; HSD-35; I79_001391; KNC-NDS6; LOW QUALITY PROTEIN: glyceraldehyde-3-phosphate dehydrogenase, testis-specific; mg:bb02e05; MGC128279 protein; MGC88685; multifunctional protein, glycolytic enzyme; OK/SW-cl.12; Peptidyl-cysteine S-nitrosylase GAPDH; similar to glyceraldehyde 3-phosphate dehydrogenase; spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2; Spermatogenic glyceraldehyde-3-phosphate dehydrogenase; Unknown (protein for IMAGE:8101613); unnamed protein product; wu:fb33a10; wu:fb71f08; wu:fk58c09; wu:ft80f05; zgc:76908

Host Species:
Mouse

Purification Method:
Size-exclusion - Membrane filtration

Regulatory Status:
RUO

Gene ID (Entrez):
2597, 26330

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA537689

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Antigen:
RBM6

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P78332

Gene Symbols:
RBM6

Immunogen:
recombinant protein of human RBM6

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
1583CT111.17.7.37

Conjugate:
Unconjugated

Gene:
RBM6

Gene Alias:
3G2; 4930506F14Rik; DEF3; DEF-3; ETK2; g16; HEK2; HLC-11; Lung cancer antigen NY-LU-12; lung cancer protooncogene 11; mKIAA4015; NY-LU-12; Protein G16; Rbm6; RGD1560367; RNA binding motif protein 6; RNA-binding motif protein 6; RNA-binding protein 6; RNA-binding protein DEF-3; TYRO6

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10180

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid