PIMA538080

ATF5 Recombinant Rabbit Monoclonal Antibody (ARC2043), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA538080-Each-of-1 In Stock ₹ 46,501.86

PIMA538080 - Each of 1

₹ 46,501.86

In Stock

Quantity

1

Base Price: ₹ 46,501.86

GST (18%): ₹ 8,370.335

Total Price: ₹ 54,872.195

Antigen

ATF5

Classification

Recombinant Monoclonal

Concentration

0.65 mg/mL

Formulation

PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

O70191, Q6P788, Q9Y2D1

Gene Symbols

Atf5

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 183-282 of human ATF5 (Q9Y2D1)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

ARC2043

Conjugate

Unconjugated

Gene

Atf5

Gene Alias

activating transcription factor 5; Activating transcription factor 5-alpha/beta; activating transcription factor 7; activating transcription factor X; AFTA; ATF5; Atf7; Atfx; BZIP protein ATF7; cAMP-dependent transcription factor ATF-5; Cyclic AMP-dependent transcription factor ATF-5; FLJ34666; HMFN0395; NAP1; NRIF3-associated protein; ODA-10; Transcription factor ATFx; transcription factor-like protein ODA-10

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

107503, 22809, 282840

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Positive Samples: HeLa, Jurkat, SH-SY5Y, Mouse liver, Mouse brain, Rat lung, Rat liver, Rat brain Immunogen sequence: PQQPPPPSPP QPSRLAPYPH PATTRGDRKQ KKRDQNKSAA LRYRQRKRAE GEALEGECQG LEARNRELKE RAESVEREIQ YVKDLLIEVY KARSQRTRSC ATF5 is a protein coding gene
  • Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), ATF5-specific response element (ARE) (consensus: 5'-C[CT]TCT[CT]CCTT[AT]-3') but also the amino acid response element (AARE), present in many viral and cellular promoters
  • Critically involved, often in a cell type-dependent manner, in cell survival, proliferation, and differentiation
  • Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4
  • Important regulator of the cerebral cortex formation, functions in cerebral cortical neuroprogenitor cells to maintain proliferation and to block differentiation into neurons
  • Must be down-regulated in order for such cells to exit the cycle and differentiate
  • Participates in the pathways by which SHH promotes cerebellar granule neuron progenitor cells proliferation
  • Critical for survival of mature olfactory sensory neurons (OSN), directs expression of OSN-specific genes
  • May be involved in osteogenic differentiation
  • Promotes cell proliferation and survival by inducing the expression of EGR1 sinergistically with ELK1
  • Once acetylated by EP300, binds to ARE sequences on target genes promoters, such as BCL2 and EGR1
  • Plays an anti-apoptotic role through the transcriptional regulation of BCL2, this function seems to be cell type-dependent
  • Cooperates with NR1I3/CAR in the transcriptional activation of CYP2B6 in liver
  • In hepatic cells, represses CRE-dependent transcription and inhibits proliferation by blocking at G2/M phase
  • May act as a negative regulator of IL1B transduction pathway in liver
  • Upon IL1B stimulus, cooperates with NLK to activate the transactivation activity of C/EBP subfamily members
  • Besides its function of transcription factor, acts as a cofactor of CEBPB to activate CEBPA and promote adipocyte differentiation
  • Regulates centrosome dynamics in a cell-cycle- and centriole-age-dependent manner
  • Forms 9-foci symmetrical ring scaffold around the mother centriole to control centrosome function and the interaction between centrioles and pericentriolar material.

Compare Similar Items

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Thermo Scientific

PIMA538080

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Antigen:
ATF5

Classification:
Recombinant Monoclonal

Concentration:
0.65 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O70191, Q6P788, Q9Y2D1

Gene Symbols:
Atf5

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 183-282 of human ATF5 (Q9Y2D1)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
ARC2043

Conjugate:
Unconjugated

Gene:
Atf5

Gene Alias:
activating transcription factor 5; Activating transcription factor 5-alpha/beta; activating transcription factor 7; activating transcription factor X; AFTA; ATF5; Atf7; Atfx; BZIP protein ATF7; cAMP-dependent transcription factor ATF-5; Cyclic AMP-dependent transcription factor ATF-5; FLJ34666; HMFN0395; NAP1; NRIF3-associated protein; ODA-10; Transcription factor ATFx; transcription factor-like protein ODA-10

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
107503, 22809, 282840

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA538081

--


Antigen:
MEIS2

Classification:
Recombinant Monoclonal

Concentration:
0.4 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O14770, P97367

Gene Symbols:
MEIS2

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MEIS2 (O14770)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ARC2049

Conjugate:
Unconjugated

Gene:
MEIS2

Gene Alias:
A430109D20Rik; Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2; homeobox protein Meis2; HsT18361; Meis homeobox 2; Meis homolog 2; Meis1, myeloid ecotropic viral integration site 1 homolog 2; Meis1-related gene 1; meis1-related protein 1; MEIS2; Meis2 homeobox; MGC2820; MRG1; myeloid ecotropic viral integration site-related gene 1; OTTHUMP00000160209; Stra10; TALE homeobox protein Meis2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17536, 4212

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA538082

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Antigen:
alpha Internexin

Classification:
Recombinant Monoclonal

Concentration:
0.13 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P23565, P46660, Q16352

Gene Symbols:
INA

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human Alpha Internexin (Q16352)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
ARC2054

Conjugate:
Unconjugated

Gene:
INA

Gene Alias:
66 kDa neurofilament protein; Alpha-internexin; alpha-Inx; AV028420; FLJ18662; FLJ57501; Ina; Inexa; internexin neuronal intermediate filament protein alpha; internexin neuronal intermediate filament protein, alpha; internexin, alpha; Intlaa; LOW QUALITY PROTEIN: alpha-internexin; MGC12702; NEF5; Neuro; Neurofilament 5; neurofilament 5 (66kD); Neurofilament 66; neurofilament-66; neurofilament-66, tax-binding protein; Nf66; NF-66; TXBP-1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
226180, 24503, 9118

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA538083

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Antigen:
FOXL2

Classification:
Recombinant Monoclonal

Concentration:
1.28 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O88470, P58012

Gene Symbols:
FOXL2

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FOXL2 (P58012)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ARC2055

Conjugate:
Unconjugated

Gene:
FOXL2

Gene Alias:
AU045128; Blepharophimosis; BPES; BPES1; epicanthus inversus; forkhead box L2; forkhead box protein L2; forkhead transcription factor; forkhead transcription factor FOXL2; forkhead transcription factor L2; Foxl2; LUSTR2; MGC14393; Pfrk; P-Frk; PINTO; pituitary forkhead factor; POF3; putative transcription factor foxl2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26927, 367152, 668

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid