PIMA538210
TIN2 Recombinant Rabbit Monoclonal Antibody (ARC1732), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA538210-Each-of-1 | In Stock | ₹ 46,501.86 |
PIMA538210 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,501.86
GST (18%): ₹ 8,370.335
Total Price: ₹ 54,872.195
Antigen
TIN2
Classification
Recombinant Monoclonal
Concentration
1.14 mg/mL
Formulation
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q9BSI4, Q9QXG9
Gene Symbols
Tinf2
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 210-309 of human TIN2/TINF2 (Q9BSI4)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Clone
ARC1732
Conjugate
Unconjugated
Gene
Tinf2
Gene Alias
AW552114; D14Wsu146e; DKCA3; TERF1 (TRF1)-interacting nuclear factor 2; TERF1 interacting nuclear factor 2; TERF1-interacting nuclear factor 2; tin; TIN2; Tin-2; TINF2; TRF1-interacting nuclear factor 2; TRF1-interacting nuclear protein 2
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
26277, 28113, 290232
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Positive Samples: HepG2, A-549, Mouse testis, Mouse thymus, Rat lung, Rat testis Immunogen sequence: NLAEPMEQNP PQQQRLALHN PLPKAKPGTH LPQGPSSRTH PEPLAGRHFN LAPLGRRRVQ SQWASTRGGH KERPTVMLFP FRNLGSPTQV ISKPESKEEH TRF1 is a negative regulator of telomere length maintenance
- Recently two proteins, tankyrase and Tin2, which bind to mammalian TRF1, have been identified
- Tankyrase is a protein with homology to ankyrins as well as to the catalytic domain of poly (adenosine diphosphate-ribose) polymerase (PARP)
- Tankyrase localizes to telomeres by binding to the telomeric repeat binding factor 1 (TRF1) through its ankyrin repeats
- Tankyrase exhibits PARP activity functioning as acceptors for adenosine diphosphate (ADP)-ribosylation
- Since ADP-ribosylation of TRF1 diminishes its ability to bind to telomeric DNA, this suggests that telomere function in human cells is regulated by poly (ADP)-ribosylation
- Both the cell cycle and TRF1 may regulate the subcellular localization of tankyrase
- The cDNA coding for TIN2 protein was isolated as interacting partner of TRF1 from a yeast two-hybrid cDNA library screening
- Tin2 localizes to telomeres and is essential for proper regulation of telomere length
- TIN2, like TRF1, is widely and constitutively expressed, suggesting that these proteins act together to counterbalance telomere elongation by telomerase
- However, endogenous TIN2, like endogenousTRF1, is not highly expressed, and therefore may be difficult to visualize by immunostaining in certain cell systems.
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Antigen: TIN2
Classification: Recombinant Monoclonal
Concentration: 1.14 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q9BSI4, Q9QXG9
Gene Symbols: Tinf2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 210-309 of human TIN2/TINF2 (Q9BSI4)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: ARC1732
Conjugate: Unconjugated
Gene: Tinf2
Gene Alias: AW552114; D14Wsu146e; DKCA3; TERF1 (TRF1)-interacting nuclear factor 2; TERF1 interacting nuclear factor 2; TERF1-interacting nuclear factor 2; tin; TIN2; Tin-2; TINF2; TRF1-interacting nuclear factor 2; TRF1-interacting nuclear protein 2
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26277, 28113, 290232
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
TIN2
Classification:
Recombinant Monoclonal
Concentration:
1.14 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q9BSI4, Q9QXG9
Gene Symbols:
Tinf2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 210-309 of human TIN2/TINF2 (Q9BSI4)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
ARC1732
Conjugate:
Unconjugated
Gene:
Tinf2
Gene Alias:
AW552114; D14Wsu146e; DKCA3; TERF1 (TRF1)-interacting nuclear factor 2; TERF1 interacting nuclear factor 2; TERF1-interacting nuclear factor 2; tin; TIN2; Tin-2; TINF2; TRF1-interacting nuclear factor 2; TRF1-interacting nuclear protein 2
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26277, 28113, 290232
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: ACVRL1
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P37023, P80203, Q61288
Gene Symbols: ACVRL1
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 404-503 of human ACVRL1 (P37023)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: ARC1735
Conjugate: Unconjugated
Gene: ACVRL1
Gene Alias: activin A receptor like type 1, activin A receptor type II-like 1, activin A receptor type IL, activin A receptor, type II-like 1, activin A receptor, type II-like kinase 1, Activin receptor like kinase 1, activin receptor-like kinase 1, activin receptor-like kinase-1, Acvrl1, Acvrlk1, AI115505, AI427544, ALK1, ALK-1, HHT, HHT2, ORW2, R3, R-3, Serine/threonine-protein kinase receptor R3, SETHKIR, SKR3, TGF-B superfamily receptor type I, TSR-I
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11482, 25237, 94
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
ACVRL1
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P37023, P80203, Q61288
Gene Symbols:
ACVRL1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 404-503 of human ACVRL1 (P37023)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
ARC1735
Conjugate:
Unconjugated
Gene:
ACVRL1
Gene Alias:
activin A receptor like type 1, activin A receptor type II-like 1, activin A receptor type IL, activin A receptor, type II-like 1, activin A receptor, type II-like kinase 1, Activin receptor like kinase 1, activin receptor-like kinase 1, activin receptor-like kinase-1, Acvrl1, Acvrlk1, AI115505, AI427544, ALK1, ALK-1, HHT, HHT2, ORW2, R3, R-3, Serine/threonine-protein kinase receptor R3, SETHKIR, SKR3, TGF-B superfamily receptor type I, TSR-I
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11482, 25237, 94
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Cdc25B
Classification: Recombinant Monoclonal
Concentration: 0.65 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P30305
Gene Symbols: CDC25B
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CDC25B (P30305)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: ARC1736
Conjugate: Unconjugated
Gene: CDC25B
Gene Alias: AI604853; CDC25B; CDC25HU2; Cdc25m2; cell division cycle 25B; dual specificity phosphatase Cdc25B; EC 3.1.3.48; M-phase inducer phosphatase 2; MPIP2
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 994
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Cdc25B
Classification:
Recombinant Monoclonal
Concentration:
0.65 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P30305
Gene Symbols:
CDC25B
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CDC25B (P30305)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
ARC1736
Conjugate:
Unconjugated
Gene:
CDC25B
Gene Alias:
AI604853; CDC25B; CDC25HU2; Cdc25m2; cell division cycle 25B; dual specificity phosphatase Cdc25B; EC 3.1.3.48; M-phase inducer phosphatase 2; MPIP2
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
994
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: HES5
Classification: Recombinant Monoclonal
Concentration: 0.9 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P70120, Q03062, Q5TA89
Gene Symbols: HES5
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 12-142 of human HES5 (Q5TA89)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: ARC1740
Conjugate: Unconjugated
Gene: HES5
Gene Alias: BHLHB38; Class B basic helix-loop-helix protein 38; hairy and enhancer of split 5; hairy and enhancer of split 5 (Drosophila); hes family bHLH transcription factor 5; Hes5; Hes-5; RP3-395M20.5; Transcription factor HES-5
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15208, 388585, 79225
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
HES5
Classification:
Recombinant Monoclonal
Concentration:
0.9 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P70120, Q03062, Q5TA89
Gene Symbols:
HES5
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 12-142 of human HES5 (Q5TA89)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
ARC1740
Conjugate:
Unconjugated
Gene:
HES5
Gene Alias:
BHLHB38; Class B basic helix-loop-helix protein 38; hairy and enhancer of split 5; hairy and enhancer of split 5 (Drosophila); hes family bHLH transcription factor 5; Hes5; Hes-5; RP3-395M20.5; Transcription factor HES-5
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15208, 388585, 79225
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid