PIMA538232

Phospho-Cyclin E (Thr77) Recombinant Rabbit Monoclonal Antibody (ARC1559), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA538232-Each-of-1 In Stock ₹ 46,501.86

PIMA538232 - Each of 1

₹ 46,501.86

In Stock

Quantity

1

Base Price: ₹ 46,501.86

GST (18%): ₹ 8,370.335

Total Price: ₹ 54,872.195

Antigen

Phospho-Cyclin E (Thr77)

Classification

Recombinant Monoclonal

Concentration

2 mg/mL

Formulation

PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q61457

Gene Symbols

CCNE1

Immunogen

A synthetic phosphorylated peptide around T77 of human Cyclin E1 (P24864)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Clone

ARC1559

Conjugate

Unconjugated

Gene

CCNE1

Gene Alias

AW538188; Ccne; Ccne1; CycE1; CYCLE; cyclin E; cyclin E1; cyclin Es; cyclin Et; E-S; G1/S-specific cyclin-E1; pCCNE1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12447

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Positive Samples: NIH/3T3 Immunogen sequence: IPTPD Cyclin E belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle
  • Cyclins function as regulators of CDK kinases
  • Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event
  • Cyclin E forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition
  • This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase
  • Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis
  • This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB
  • Two alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been described
  • Two additional splice variants were reported but detailed nucleotide sequence information is not yet available.

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Img

Thermo Scientific

PIMA538232

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Antigen:
Phospho-Cyclin E (Thr77)

Classification:
Recombinant Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q61457

Gene Symbols:
CCNE1

Immunogen:
A synthetic phosphorylated peptide around T77 of human Cyclin E1 (P24864)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ARC1559

Conjugate:
Unconjugated

Gene:
CCNE1

Gene Alias:
AW538188; Ccne; Ccne1; CycE1; CYCLE; cyclin E; cyclin E1; cyclin Es; cyclin Et; E-S; G1/S-specific cyclin-E1; pCCNE1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12447

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA538235

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Antigen:
Phospho-GSK3B (Ser9)

Classification:
Recombinant Monoclonal

Concentration:
0.33 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P49841, Q9WV60

Gene Symbols:
GSK3B

Immunogen:
A synthetic phosphorylated peptide around S9 of human GSK3 beta (P49841)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
ARC0069

Conjugate:
Unconjugated

Gene:
GSK3B

Gene Alias:
7330414F15Rik; 8430431H08Rik; C86142; EC 2.7.11.26; FA; Factor A; fb68h05; fk80d11; glycogen synthase kinase 3; glycogen synthase kinase 3 beta; glycogen synthase kinase 3 beta L homeolog; glycogen synthase kinase 3 beta variant 1; glycogen synthase kinase 3 beta variant 2; glycogen synthase kinase 3 beta variant 3; glycogen synthase kinase 3 beta variant 4; glycogen synthase kinase 3 beta variant 5; glycogen synthase kinase 3 beta, genome duplicate a; glycogen synthase kinase-3 beta; glycogen synthase kinase-3 beta splice variant X1; glycogen synthase kinase-3 beta splice variant X2; glycogen synthase kinase-3 beta splice variant X3; GSK 3 beta; GSK 3B; gsk3; GSK-3; GSK3 beta; GSK-3 beta; GSK-3 beta GSK3B; GSK-3[b]; Gsk3b; GSK-3b; gsk3b.L; gsk3ba; gsk3beta; GSK-3beta; gsk3-beta; GSK3beta isoform; intracellular kinase; pp37; serine/threonine-protein kinase GSK3B; wu:fb68h05; wu:fk80d11; XELAEV_180112401mg; xgsk-3; Xgsk-3 protein

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2932, 56637

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA538236

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Antigen:
Phospho-PKR (Thr446)

Classification:
Recombinant Monoclonal

Concentration:
0.8 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P19525

Gene Symbols:
EIF2AK2

Immunogen:
A synthetic phosphorylated peptide around T446 of human PKR/EIF2AK2E2AK2 (P19525)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ARC0293

Conjugate:
Unconjugated

Gene:
EIF2AK2

Gene Alias:
2310047A08Rik; 4732414G15Rik; AI467567; AI747578; double stranded RNA activated protein kinase; dsRNA-activated kinase; EC 2.7.11.1; eIF-2 alpha; eIF2a Kinase; eIF-2A protein kinase 2; EIF2AK1; EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2; eukaryotic translation initiation factor 2-alpha kinase 2; IFN- type I-induced and dsRNA-activated kinase; IFN-induced and double-stranded RNA-activated kinase; interferon-induced, double-stranded RNA-activated protein kinase; interferon-inducible elF2alpha kinase; interferon-inducible RNA-dependent protein kinase; MGC126524; OTTHUMP00000201320; P1/eIF-2A protein kinase; p68 kinase; PKR; PPP1R83; Prkr; protein kinase R; protein kinase RNA-activated; protein kinase, interferon inducible double stranded RNA dependent; Protein kinase, interferon-inducible double stranded RNA dependent; protein phosphatase 1, regulatory subunit 83; serine/threonine-protein kinase TIK; T-cell viral integration site; Tik; Tyrosine-protein kinase EIF2AK2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5610

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA538237

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Antigen:
Phospho-Cdc6 (Ser54)

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O89033

Gene Symbols:
CDC6

Immunogen:
A synthetic phosphorylated peptide around S54 of human Cdc6 (Q99741)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ARC1693

Conjugate:
Unconjugated

Gene:
CDC6

Gene Alias:
CDC18(S.pombe); CDC18L; cdc18-related protein; CDC6; CDC6 cell division cycle 6 homolog; CDC6-related protein; Cell division control protein 6 homolog; cell division cycle 6; cell division cycle 6 homolog; HsCDC18; HsCDC6; p62(cdc6)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23834

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid