PIMA538308

USP7 Recombinant Rabbit Monoclonal Antibody (7F10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA538308-Each-of-1 In Stock ₹ 51,036.54

PIMA538308 - Each of 1

₹ 51,036.54

In Stock

Quantity

1

Base Price: ₹ 51,036.54

GST (18%): ₹ 9,186.577

Total Price: ₹ 60,223.117

Antigen

USP7

Classification

Recombinant Monoclonal

Concentration

0.8 mg/mL

Formulation

PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q93009

Gene Symbols

USP7

Immunogen

A synthesized peptide derived from human HAUSP / USP7

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

7F10

Conjugate

Unconjugated

Gene

USP7

Gene Alias

2210010O09Rik; AA409944; AA617399; AU019296; AW548146; C80752; deubiquitinating enzyme 7; Hausp; Herpes virus-associated ubiquitin-specific protease; herpes-virus-associated ubiquitin-specific protease; herpesvirus-associated ubiquitin-specific protease; mHAUSP; protease; rHAUSP; TEF1; Ubiquitin carboxyl-terminal hydrolase 7; ubiquitin specific peptidase 7; ubiquitin specific peptidase 7 (herpes virus-associated); ubiquitin specific protease 7; ubiquitin specific protease 7 (herpes virus-associated); ubiquitin thioesterase 7; ubiquitin thiolesterase 7; ubiquitin-specific-processing protease 7; UBP; USP7

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7874

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

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Description

  • This antibody has been tested in direct-ELISA USP7 or HAUSP is a ubiquitin specific protease or a deubiquitylating enzyme that cleaves ubiquitin from its substrates
  • Since ubiquitylation (polyubiquitination) is most commonly associated with the stability and degradation of cellular proteins, HAUSP activity generally stabilizes its substrate proteins
  • HAUSP is most popularly known as a direct antagonist of Mdm2, the E3 ubiquitin ligase for the tumor suppressor protein, p53
  • Normally, p53 levels are kept low in part due to Mdm2-mediated ubiquitylation and degradation of p53
  • Interestingly, in response to oncogenic insults, HAUSP can deubiquitinate p53 and protect p53 from Mdm2-mediated degradation, indicating that it may possess a tumor suppressor function for the immediate stabilization of p53 in response to stress
  • Another important role of HAUSP function involves the oncogenic stabilization of p53
  • Oncogenes such as Myc and E1A are thought to activate p53 through a p19 alternative reading frame (p19ARF, also called ARF)-dependent pathway, although some evidence suggests ARF is not essential in this process
  • An intriguing possibility is that HAUSP provides an alternative pathway for safeguarding the cell against oncogenic insults.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA538308

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Antigen:
USP7

Classification:
Recombinant Monoclonal

Concentration:
0.8 mg/mL

Formulation:
PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q93009

Gene Symbols:
USP7

Immunogen:
A synthesized peptide derived from human HAUSP / USP7

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
7F10

Conjugate:
Unconjugated

Gene:
USP7

Gene Alias:
2210010O09Rik; AA409944; AA617399; AU019296; AW548146; C80752; deubiquitinating enzyme 7; Hausp; Herpes virus-associated ubiquitin-specific protease; herpes-virus-associated ubiquitin-specific protease; herpesvirus-associated ubiquitin-specific protease; mHAUSP; protease; rHAUSP; TEF1; Ubiquitin carboxyl-terminal hydrolase 7; ubiquitin specific peptidase 7; ubiquitin specific peptidase 7 (herpes virus-associated); ubiquitin specific protease 7; ubiquitin specific protease 7 (herpes virus-associated); ubiquitin thioesterase 7; ubiquitin thiolesterase 7; ubiquitin-specific-processing protease 7; UBP; USP7

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7874

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

PIMA538310

--


Antigen:
GATA3

Classification:
Recombinant Monoclonal

Concentration:
1.2 mg/mL

Formulation:
PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P23771

Gene Symbols:
GATA3

Immunogen:
A synthesized peptide derived from human GATA3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
2A9

Conjugate:
Unconjugated

Gene:
GATA3

Gene Alias:
EGK_19445; GATA binding factor-3; GATA binding protein 3; GATA binding protein-3; GATA3; Gata-3; GATA-binding factor 3; GATA-binding protein 3; HDR; HDRS; jal; MGC2346; MGC5199; MGC5445; Trans-acting T-cell-specific transcription factor GATA-3; Transacting T-cell-specific transcription factor GATA-3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2625

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

PIMA538313

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Antigen:
PCYT1A

Classification:
Recombinant Monoclonal

Concentration:
1.05 mg/mL

Formulation:
PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P49585

Gene Symbols:
PCYT1A

Immunogen:
A synthesized peptide derived from human PCYT1A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
4F2

Conjugate:
Unconjugated

Gene:
PCYT1A

Gene Alias:
CCT A; CCTA; Cctalpha; CCT-alpha; choline phosphate cytidylyltransferase 1 alpha; choline-phosphate cytidylyltransferase A; CT; CT A; CTA; CTalpha; CTP; CTP phosphocholine cytidylyl transferase; CTP:phosphocholine cytidylyl transferase; CTP:phosphocholine cytidylyltransferase A; CTP:phosphocholine cytidylyltransferase alpha; Ctpct; Cttalpha; PCYT1; PCYT1A; phosphate cytidylyltransferase 1, choline, alpha; phosphate cytidylyltransferase 1, choline, alpha isoform; phosphorylcholine transferase A; SMDCRD

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5130

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

PIMA538314

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Antigen:
Arp3

Classification:
Recombinant Monoclonal

Concentration:
0.58 mg/mL

Formulation:
PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P61158, Q4V7C7, Q99JY9

Gene Symbols:
ACTR3

Immunogen:
A synthesized peptide derived from human Arp3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
7E5

Conjugate:
Unconjugated

Gene:
ACTR3

Gene Alias:
1200003A09Rik; Actin-like protein 3; actin-related protein 3; actin-related protein 3 homolog (yest); ACTR3; Arp3; ARP3 actin related protein 3 homolog; ARP3 actin-related protein 3; ARP3 actin-related protein 3 homolog; ARP3 actin-related protein 3 homolog (yeast)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10096, 74117, 81732

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid