PIMA538324

Aurora B Recombinant Rabbit Monoclonal Antibody (4E5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA538324-Each-of-1 In Stock ₹ 51,036.54

PIMA538324 - Each of 1

₹ 51,036.54

In Stock

Quantity

1

Base Price: ₹ 51,036.54

GST (18%): ₹ 9,186.577

Total Price: ₹ 60,223.117

Antigen

Aurora B

Classification

Recombinant Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q96GD4

Gene Symbols

AURKB

Immunogen

A synthesized peptide derived from human Aurora B

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

4E5

Conjugate

Unconjugated

Gene

AURKB

Gene Alias

Aik2; AIM1; AIM-1; AIRK2; AL022959; ARK2; ARK-2; AurB; AURKB; aurkb-sv1; aurkb-sv2; aurora 1; aurora- and IPL1-like midbody-associated protein 1; aurora B; aurora kinase B; aurora kinase B-Sv1; aurora kinase B-Sv2; aurora/IPL1-related kinase 2; aurora-1; aurora-B; aurora-related kinase 2; IPL1; PPP1R48; protein phosphatase 1, regulatory subunit 48; serine/threonine kinase; serine/threonine kinase 12; serine/threonine kinase 5; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5; serine/threonine-protein kinase aurora-B; STK1; STK-1; Stk12; STK12; AIK2; AIM1; ARK2; IPL1; AIM-1; STK5

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9212

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

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Description

  • This antibody has been tested in direct-ELISA The Aurora kinases associate with microtubules during chromosome movement and segregation
  • AURKB (Aurora B) localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers
  • This complex functions in chromosome alignment and separation, histone modification, and cytokinesis
  • CPC also includes three non-enzymatic subunits known as the inner centromere protein (INCENP), survivin, and borealin, which determine the activity, localization, stability, and possibly even the substrate specificity of AurB
  • Two CPCs exist during mitosis: one containing all four members and another consisting of INCENP and AurB
  • Quaternary CPC functions during chromosome alignment and cytokinesis, whereas the INCENP-AurB complex may be responsible for modifying histone H3
  • AurB is overexpressed in a number of tumours, including primary breast and colon tumour samples
  • Its expression in tumours seems to be linked with Aurora-A kinase, suggesting a feedback mechanism between the two proteins.

Compare Similar Items

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Img

Thermo Scientific

PIMA538324

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Antigen:
Aurora B

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q96GD4

Gene Symbols:
AURKB

Immunogen:
A synthesized peptide derived from human Aurora B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
4E5

Conjugate:
Unconjugated

Gene:
AURKB

Gene Alias:
Aik2; AIM1; AIM-1; AIRK2; AL022959; ARK2; ARK-2; AurB; AURKB; aurkb-sv1; aurkb-sv2; aurora 1; aurora- and IPL1-like midbody-associated protein 1; aurora B; aurora kinase B; aurora kinase B-Sv1; aurora kinase B-Sv2; aurora/IPL1-related kinase 2; aurora-1; aurora-B; aurora-related kinase 2; IPL1; PPP1R48; protein phosphatase 1, regulatory subunit 48; serine/threonine kinase; serine/threonine kinase 12; serine/threonine kinase 5; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5; serine/threonine-protein kinase aurora-B; STK1; STK-1; Stk12; STK12; AIK2; AIM1; ARK2; IPL1; AIM-1; STK5

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9212

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

PIMA538325

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Antigen:
Dot1L

Classification:
Recombinant Monoclonal

Concentration:
1.5 mg/mL

Formulation:
PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8TEK3

Gene Symbols:
Dot1l

Immunogen:
A synthesized peptide derived from human KMT4 / Dot1L

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
3B6

Conjugate:
Unconjugated

Gene:
Dot1l

Gene Alias:
A630076O07; AW907654; DKFZp586P1823; DOT1; DOT1 like histone H3K79 methyltransferase; DOT1 like histone lysine methyltransferase; DOT1L; DOT1-like histone H3 methyltransferase; DOT1-like histone H3K79 methyltransferase; DOT1-like protein; DOT1-like, histone H3 methyltransferase; DOT1-like, histone H3 methyltransferase (S. cerevisiae); H3-K79-HMTase; histone H3 methyltransferase DOT1; histone H3-K79 methyltransferase; histone methyltransferase DOT1L; histone-lysine N-methyltransferase, H3 lysine-79 specific; KIAA1814; KMT4; lysine N-methyltransferase 4; mDot1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84444

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

PIMA538327

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Antigen:
CD80

Classification:
Recombinant Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P33681

Gene Symbols:
CD80

Immunogen:
A synthesized peptide derived from human CD80

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
3C3

Conjugate:
Unconjugated

Gene:
CD80

Gene Alias:
Activation B7-1 antigen; B7; B7 protein; B7.1; B71; B7-1; B7-1 protein; B7-1 protein precursor; BB1; B-lymphocyte activation antigen B7; Cd28l; CD28LG; CD28LG1; CD80; Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1); CD80 anitgen; CD80 antigen; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); Cd80 molecule; CD80 protein precursor; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; Ly53; Ly-53; MIC17; sCD 80; sCD80; secreted B7-1 protein precursor; soluble CD 80; soluble CD80; T-cell costimulatory molecule; T-cell co-stimulatory protein B7-1; T-lymphocyte activation antigen CD80; TS/A-1; TSA1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
941

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

PIMA538328

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Antigen:
Bcl-xL

Classification:
Recombinant Monoclonal

Concentration:
0.46 mg/mL

Formulation:
PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P53563, Q07817, Q64373

Gene Symbols:
BCL2L1

Immunogen:
A synthesized peptide derived from human Bcl-XL

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
5E9

Conjugate:
Unconjugated

Gene:
BCL2L1

Gene Alias:
anti-apoptosis regulatory protein; apoptosis regulator Bcl-X; B cell lymphoma 2 like; B cell lymphoma like X; B-cell leukemia/lymphoma x; Bcl(X)L; BCL2 like 1; Bcl2l; BCL2L1; bcl2-L-1; BCL2-like 1; Bcl-2-like protein 1; BCLX; bcl-x; BCLXL; Bcl-XL; BCL-XL/S; BCLXS; bcl-xS; Blc2l; DKFZp781P2092; EGK_02534; OTTHUMP00000030550; OTTHUMP00000030552; OTTHUMP00000030555; OTTHUMP00000030556; OTTHUMP00000030557; PPP1R52; protein phosphatase 1, regulatory subunit 52; RP5-857M17.3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12048, 24888, 598

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid