PIMA538329

FAS Recombinant Rabbit Monoclonal Antibody (2B6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA538329-Each-of-1 In Stock ₹ 51,036.54

PIMA538329 - Each of 1

₹ 51,036.54

In Stock

Quantity

1

Base Price: ₹ 51,036.54

GST (18%): ₹ 9,186.577

Total Price: ₹ 60,223.117

Antigen

FAS

Classification

Recombinant Monoclonal

Concentration

0.6 mg/mL

Formulation

PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P25445

Gene Symbols

FAS

Immunogen

A synthesized peptide derived from human Fas

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

2B6

Conjugate

Unconjugated

Gene

FAS

Gene Alias

AI196731; ALPS1A; APO1; APO-1; Apo1 antigen; Apo-1 antigen; APO-1 cell surface antigen; Apo-1 Fas; apoptosis antigen 1; apoptosis signaling receptor FAS; apoptosis-mediating surface antigen FAS; APT1; CD95; CD95 antigen; FAS; Fas (TNF receptor superfamily member 6); Fas (TNF receptor superfamily member); Fas (TNF receptor superfamily, member 6); Fas AMA; Fas antigen; Fas antigen (ATP1); Fas cell surface death receptor; Fas receptor; FAS1; FASLG receptor; FASTM; lpr; lymphoproliferation; OTTHUMP00000020045; OTTHUMP00000020046; OTTHUMP00000020051; OTTHUMP00000059646; TNF receptor superfamily member 6; TNFR6; Tnfrsf6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 26; Tumor necrosis factor receptor superfamily, member 6

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

355

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

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Description

  • This antibody has been tested in direct-ELISA FAS (Fas, CD95, APO-1) is a 46 kDa transmembrane glycoprotein that functions as a cell death receptor of the TNFR (tumor necrosis factor receptor) superfamily
  • FAS also exists in a soluble form that weight approximately 26kDa
  • Stimulation of FAS results in aggregation of its intracellular FAS-associated death domains (FADD), formation of the death-inducing signaling complex (DISC) and activation of caspases
  • The auto-proteolytic processing of the caspases in the complex trigger a downstream cascade that leads to apoptosis
  • FAS has been shown to activate NF-kappaB, MAPK3/ERK1, MAPK8/JNK, and is involved in transducing the proliferating signals in normal diploid fibroblast and T cells
  • At least eight alternatively spliced transcript variants encoding seven distinct isoforms have been described
  • The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full-length isoform
  • The Fas/Fas ligand system has been shown to play a role in a number of human diseases such as AIDS, hepatitis and cancer
  • It is also assumed that induction of apoptosis through FAS ligand pathway is predominantly involved in anti-viral immune responses.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA538329

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Antigen:
FAS

Classification:
Recombinant Monoclonal

Concentration:
0.6 mg/mL

Formulation:
PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P25445

Gene Symbols:
FAS

Immunogen:
A synthesized peptide derived from human Fas

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
2B6

Conjugate:
Unconjugated

Gene:
FAS

Gene Alias:
AI196731; ALPS1A; APO1; APO-1; Apo1 antigen; Apo-1 antigen; APO-1 cell surface antigen; Apo-1 Fas; apoptosis antigen 1; apoptosis signaling receptor FAS; apoptosis-mediating surface antigen FAS; APT1; CD95; CD95 antigen; FAS; Fas (TNF receptor superfamily member 6); Fas (TNF receptor superfamily member); Fas (TNF receptor superfamily, member 6); Fas AMA; Fas antigen; Fas antigen (ATP1); Fas cell surface death receptor; Fas receptor; FAS1; FASLG receptor; FASTM; lpr; lymphoproliferation; OTTHUMP00000020045; OTTHUMP00000020046; OTTHUMP00000020051; OTTHUMP00000059646; TNF receptor superfamily member 6; TNFR6; Tnfrsf6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 26; Tumor necrosis factor receptor superfamily, member 6

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
355

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

PIMA538331

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Antigen:
ID1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P20067, P41134

Gene Symbols:
ID1

Immunogen:
A synthesized peptide derived from human Id1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
2C7

Conjugate:
Unconjugated

Gene:
ID1

Gene Alias:
AI323524; bHLHb24; class B basic helix-loop-helix protein 24; D2Wsu140e; dJ857M17.1.2; dJ857M17.1.2 (inhibitor of DNA binding 1, dominant negative helix-loop-helix protein); DNA-binding protein inhibitor ID-1; ID; ID1; Id-1; ID125A; Idb1; inhibitor of differentiation 1; Inhibitor of DNA binding 1; Inhibitor of DNA binding 1 helix-loop-helix protein (splice varaiation); inhibitor of DNA binding 1, dominant negative helix-loop-helix protein; Inhibitor of DNA binding 1, helix-loop-helix protein (splice variation); inhibitor of DNA binding 1, HLH protein

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15901, 3397

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

PIMA538332

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Antigen:
IKK beta

Classification:
Recombinant Monoclonal

Concentration:
0.48 mg/mL

Formulation:
PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O14920

Gene Symbols:
Ikbkb

Immunogen:
A synthesized peptide derived from human IKK beta

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
3E1

Conjugate:
Unconjugated

Gene:
Ikbkb

Gene Alias:
AI132552; AIM-1; FLJ40509; I-kappa-B kinase 2; I-kappa-B-kinase beta; Ikbkb; IKK[b]; IKK2; IKK-2; IKKB; IKK-B; IKKbeta; IKK-beta; IMD15; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of kappaB kinase beta; inhibitor of nuclear factor kappa B kinase beta subunit; inhibitor of nuclear factor kappa-B kinase subunit beta; MGC131801; NFKBIKB; nuclear factor NF-kappa-B inhibitor kinase beta

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3551

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

PIMA538333

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Antigen:
AGTR1

Classification:
Recombinant Monoclonal

Concentration:
0.86 mg/mL

Formulation:
PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P30556

Gene Symbols:
AGTR1

Immunogen:
A synthesized peptide derived from human AGTR1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
4A9

Conjugate:
Unconjugated

Gene:
AGTR1

Gene Alias:
1810074K20Rik; AG2S; AGTR1; Agtr1a; Agtr-1a; AGTR1B; AI551199; angiotensin II receptor type 1; angiotensin II receptor, type 1; angiotensin II receptor, type 1a; Angiotensin II type-1 receptor; Angiotensin II type-1A receptor; angiotensin receptor 1; angiotensin receptor 1a; Angtr-1a; AT1; At1a; AT1AR; AT1B; AT1BR; AT1R; AT2R1; AT2R1A; AT2R1B; HAT1R; Type-1 angiotensin II receptor; Type-1A angiotensin II receptor; type-1B angiotensin II receptor; vascular type-1 angiotensin II receptor

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
185

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid