PIMA538553

HRX Monoclonal Antibody (4A5A12), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA538553-Each-of-1 In Stock ₹ 46,501.86

PIMA538553 - Each of 1

₹ 46,501.86

In Stock

Quantity

1

Base Price: ₹ 46,501.86

GST (18%): ₹ 8,370.335

Total Price: ₹ 54,872.195

Antigen

HRX

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

Q03164

Gene Symbols

KMT2A

Immunogen

Purified recombinant fragment of human KMT2A (aa: 801-956) expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Western Blot

Clone

4A5A12

Conjugate

Unconjugated

Gene

KMT2A

Gene Alias

6430520K01; ALL1; ALL-1; CDK6/MLL fusion protein; C-terminal cleavage product of 180 kDa; CXXC7; CXXC-type zinc finger protein 7; histone-lysine N-methyltransferase 2A; histone-lysine N-methyltransferase MLL; HRX; HTRX; HTRX1; Kmt2a; lysine (K)-specific methyltransferase 2A; lysine methyltransferase 2A; lysine N-methyltransferase 2A; mixed lineage leukemia 1; mKIAA4050; Mll; MLL cleavage product C180; MLL cleavage product N320; MLL/ENL fusion protein; MLL/GAS7; MLL/GAS7 fusion protein; MLL/GMPS fusion protein; MLL/hCDCrel fusion protein; MLL1; MLL1A; MLL-AF4 der(11) fusion protein; MLL-AF9; Myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); myeloid/lymphoid or mixed-lineage leukemia 1; myeloid/lymphoid or mixed-lineage leukemia protein 1; N-terminal cleavage product of 320 kDa; p180; p320; rearranged MLL protein; TET1-MLL; trithorax Drosophila; trithorax-like protein; TRX1; WDSTS; zinc finger protein HRX

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

4297

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody has been tested in indirect ELISA
  • KMT2A is a histone methyltransferase that plays an essential role in early development and hematopoiesis
  • It is a catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac)
  • In the MLL1/MLL complex, KMT2A specifically mediates H3K4me, a tag for epigenetic transcriptional activation
  • KMT2A has weak methyltransferase activity by itself, and requires other components of the MLL1/MLL complex to obtain full methyltransferase activity
  • It has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', and has higher activity toward H3 acetylated on 'Lys-9'
  • Required for transcriptional activation of HOXA9 and promotes PPP1R15A-induced apoptosis.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA538553

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Antigen:
HRX

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q03164

Gene Symbols:
KMT2A

Immunogen:
Purified recombinant fragment of human KMT2A (aa: 801-956) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Western Blot

Clone:
4A5A12

Conjugate:
Unconjugated

Gene:
KMT2A

Gene Alias:
6430520K01; ALL1; ALL-1; CDK6/MLL fusion protein; C-terminal cleavage product of 180 kDa; CXXC7; CXXC-type zinc finger protein 7; histone-lysine N-methyltransferase 2A; histone-lysine N-methyltransferase MLL; HRX; HTRX; HTRX1; Kmt2a; lysine (K)-specific methyltransferase 2A; lysine methyltransferase 2A; lysine N-methyltransferase 2A; mixed lineage leukemia 1; mKIAA4050; Mll; MLL cleavage product C180; MLL cleavage product N320; MLL/ENL fusion protein; MLL/GAS7; MLL/GAS7 fusion protein; MLL/GMPS fusion protein; MLL/hCDCrel fusion protein; MLL1; MLL1A; MLL-AF4 der(11) fusion protein; MLL-AF9; Myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); myeloid/lymphoid or mixed-lineage leukemia 1; myeloid/lymphoid or mixed-lineage leukemia protein 1; N-terminal cleavage product of 320 kDa; p180; p320; rearranged MLL protein; TET1-MLL; trithorax Drosophila; trithorax-like protein; TRX1; WDSTS; zinc finger protein HRX

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
4297

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA538554

--


Antigen:
KMT2C

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q8NEZ4

Gene Symbols:
KMT2C

Immunogen:
Purified recombinant fragment of human KMT2C (aa: 1-205) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
6D1B9

Conjugate:
Unconjugated

Gene:
KMT2C

Gene Alias:
2.1.1.43; ALR-like protein; HALR; Histone-lysine N-methyltransferase 2C; histone-lysine N-methyltransferase MLL3; histone-lysine N-methyltransferase, H3 lysine-4 specific; homologous to ALR protein; KIAA1506; KMT2C; lysine (K)-specific methyltransferase 2C; lysine methyltransferase 2C; Lysine N-methyltransferase 2C; MLL3; Myeloid/lymphoid or mixed-lineage leukemia protein 3

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
58508

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA538556

--


Antigen:
LDLR

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P01130

Gene Symbols:
LDLR

Immunogen:
Purified recombinant fragment of human LDLR (aa: 22-150) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
1B10H10

Conjugate:
Unconjugated

Gene:
LDLR

Gene Alias:
FH; FHC; Hlb301; I79_005860; LDL receptor; LDLA; LDLCQ2; LDLR; ldl-r; LDLRA; low density lipoprotein receptor; low density lipoprotein receptor protein; low-density lipoprotein receptor; low-density lipoprotein receptor class A domain-containing protein 3

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3949

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA538557

--


Antigen:
LILRA1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O75019

Gene Symbols:
LILRA1

Immunogen:
Purified recombinant fragment of human LILRA1 (aa: extra 322-461) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
4A1E10A6

Conjugate:
Unconjugated

Gene:
LILRA1

Gene Alias:
CD85 antigen-like family member I; CD85I; leucocyte Ig-like receptor A1; leukocyte immunoglobulin like receptor A1; leukocyte immunoglobulin-like receptor 6; Leukocyte immunoglobulin-like receptor subfamily A member 1; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1; LILRA1; LIR6; LIR-6

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11024

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid