PIMA538618

RAD18 Monoclonal Antibody (2G8D12), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA538618-Each-of-1 In Stock ₹ 46,501.86

PIMA538618 - Each of 1

₹ 46,501.86

In Stock

Quantity

1

Base Price: ₹ 46,501.86

GST (18%): ₹ 8,370.335

Total Price: ₹ 54,872.195

Antigen

RAD18

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

Q9NS91

Gene Symbols

Rad18

Immunogen

Purified recombinant fragment of human RAD18 (aa: 332-430) expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Flow Cytometry, Western Blot

Clone

2G8D12

Conjugate

Unconjugated

Gene

Rad18

Gene Alias

2810024C04Rik; E3 ubiquitin-protein ligase RAD18; hHR18; hRAD18; mRAD18Sc; postreplication repair protein hRAD18p; postreplication repair protein RAD18; post-replication repair protein RAD18SC; Rad18; RAD18 E3 ubiquitin protein ligase; RAD18 homolog; RAD18 homolog (S. cerevisiae); RAD18, E3 ubiquitin protein ligase; RAD18, S. cerevisiae, homolog; Rad18sc; RING finger protein 73; RING-type E3 ubiquitin transferase RAD18; RNF73

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

56852

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody has been tested in indirect ELISA
  • Human Rad18 (hRad18) is homologue of the S
  • pombe Rad18 (3,4)
  • In yeast, Rad6 and Rad18 play a crucial role in post-replication repair functions in gap-filling of a daughter strand on replication of damaged DNA (2)
  • Furthermore, Rad6-Rad18 interaction is thought to be critical at an early step during lesion bypass in yeast
  • In vivo, Rad18 protein forms a tight complex with Rad6 through a conserved ring-finger motif (3,4)
  • It has been suggested that Rad18-Rad6 complex binds to the damaged sites by the single-stranded DNA binding property of Rad 18
  • This is followed by degradation of the stalled components of DNA replication by ubiquitin-conjugating enzyme activity of Rad6 (1)
  • The human Rad18 maps on chromosome 3p24-25, the region which is often deleted in lung, breast, ovary, and testis cancers
  • The human RAD18 gene codes for a protein of 495 amino acids with a predicted molecular weight of 56 kDa
  • The human Rad18 is ubiquitously expressed in various human tissues.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA538618

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Antigen:
RAD18

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q9NS91

Gene Symbols:
Rad18

Immunogen:
Purified recombinant fragment of human RAD18 (aa: 332-430) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
2G8D12

Conjugate:
Unconjugated

Gene:
Rad18

Gene Alias:
2810024C04Rik; E3 ubiquitin-protein ligase RAD18; hHR18; hRAD18; mRAD18Sc; postreplication repair protein hRAD18p; postreplication repair protein RAD18; post-replication repair protein RAD18SC; Rad18; RAD18 E3 ubiquitin protein ligase; RAD18 homolog; RAD18 homolog (S. cerevisiae); RAD18, E3 ubiquitin protein ligase; RAD18, S. cerevisiae, homolog; Rad18sc; RING finger protein 73; RING-type E3 ubiquitin transferase RAD18; RNF73

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
56852

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA538619

--


Antigen:
RAD50

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q92878, Q9JIL8

Gene Symbols:
RAD50

Immunogen:
Purified recombinant fragment of human RAD50 (aa: 228-359) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
3D2G10

Conjugate:
Unconjugated

Gene:
RAD50

Gene Alias:
153 kDa protein; DNA repair protein RAD50; hRad50; hsRAD50; I79_004319; mRad50; Mrell; MRX complex DNA-binding subunit; N0872; NBSLD; Rad50; RAD50 2; RAD50 double strand break repair protein; RAD50 homolog (S. cerevisiae); RAD50 homolog, double strand break repair protein; RAD50 PEN; RAD502; RAD50-2; RAD50-3; Rad50l; YNL250W

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10111, 64012

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA538622

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Antigen:
RAP1GAP

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P47736

Gene Symbols:
RAP1GAP

Immunogen:
Purified recombinant fragment of human RAP1GAP (aa: 412-678) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
2G7B6

Conjugate:
Unconjugated

Gene:
RAP1GAP

Gene Alias:
1300019I11Rik; 2310004O14Rik; AI427470; ARPP-90; KIAA0474; RAP1 GTPase activating protein; Rap1 GTPase-activating protein; rap1 GTPase-activating protein 1; Rap1, GTPase-activating protein 1; Rap1ga1; Rap1GAP; Rap1GAP1; RAP1GAPII; RAPGAP

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5909

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA538624

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Antigen:
eRF1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P62495

Gene Symbols:
ETF1

Immunogen:
Purified recombinant fragment of human RF1 (aa: 288-437) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
4F9H12

Conjugate:
Unconjugated

Gene:
ETF1

Gene Alias:
AI463371; D5S1995; D6Ertd109e; ERF; ERF1; ETF1; Eukaryotic peptide chain release factor subunit 1; eukaryotic release factor 1; eukaryotic translation termination factor 1; polypeptide chain release factor 1; protein Cl1; RF1; sup45 (yeast omnipotent suppressor 45) homolog-like 1; SUP45L1; TB3-1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
2107

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid