PIMA538755

CD86 Monoclonal Antibody (BU63), PE-Cyanine7, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA538755-Each-of-1 In Stock ₹ 34,737.36

PIMA538755 - Each of 1

₹ 34,737.36

In Stock

Quantity

1

Base Price: ₹ 34,737.36

GST (18%): ₹ 6,252.725

Total Price: ₹ 40,990.085

Antigen

CD86

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.

P42081

Gene Symbols

CD86

Immunogen

B-lymphoblastoid cell line ARH 77

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Flow Cytometry

Clone

BU63

Conjugate

PE-Cyanine7

Gene

CD86

Gene Alias

activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

Host Species

Mouse

Purification Method

Size-exclusion chromatography

Regulatory Status

RUO

Gene ID (Entrez)

942

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Isotype

IgG1

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Description

  • Do not use after expiration date stamped on vial label
  • CD86 is one of two ligands (the other CD80) for CTLA4 and CD28
  • CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation
  • Antigen presentation in the absence of sufficient co-stimulation involving CD86/CD80 can induce tolerance
  • CD80 appears to play a role distinct from CD80 in T helper cell differentiation
  • CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily
  • The CD86 protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4
  • Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell
  • Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response
  • Alternative splicing results in two transcript variants encoding different isoforms of CD86
  • Additional transcript variants have been described for CD86, but their full-length sequences have not been determined
  • Diseases associated with CD86 dysfunction include gallbladder squamous cell carcinoma and myocarditis.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA538755

--


Antigen:
CD86

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P42081

Gene Symbols:
CD86

Immunogen:
B-lymphoblastoid cell line ARH 77

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry

Clone:
BU63

Conjugate:
PE-Cyanine7

Gene:
CD86

Gene Alias:
activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
942

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG1

Img

Thermo Scientific

PIMA540909

--


Antigen:
15-PGDH

Classification:
Recombinant Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 0.5% BSA and 0.09% sodium azide

Gene Accession No.:
P15428

Gene Symbols:
HPGD

Immunogen:
Recombinant Human HPGD/15-PGDH protein

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry

Clone:
027

Conjugate:
FITC

Gene:
HPGD

Gene Alias:
15-hydroxyprostaglandin dehydrogenase; 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; 15-PGDH; AV026552; HPGD; hydroxyprostaglandin dehydrogenase 15 (NAD); hydroxyprostaglandin dehydrogenase 15-(NAD); NAD+-dependent 15-hydroxyprostaglandin dehydrogenase; NAD-dependent 15-hydroxyprostaglandin dehydrogenase; PGDH; PGDH1; PHOAR1; Prostaglandin dehydrogenase 1; SDR36C1; Short chain dehydrogenase/reductase family 36C member 1; short chain dehydrogenase/reductase family 36C, member 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3248

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG

Img

Thermo Scientific

PIMA540911

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Antigen:
ADAM15

Classification:
Recombinant Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 0.5% BSA and 0.03% ProClin 300

Gene Accession No.:
Q13444

Gene Symbols:
Adam15

Immunogen:
Recombinant Human ADAM15 protein

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry

Clone:
007

Conjugate:
APC

Gene:
Adam15

Gene Alias:
a disintegrin and metallopeptidase domain 15 (metargidin); a disintegrin and metalloprotease domain 15 (metargidin); a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 15; a disintegrin and metalloproteinase domain 15 (metargidin); AD56; ADAM; ADAM 15; ADAM metallopeptidase domain 15; Adam15; ADAMs; CRII-7; disintegrin and metalloprotease 15; disintegrin and metalloproteinase domain-containing protein 15; Mdc15; MDC-15; metalloendopeptidases; Metalloprotease RGD disintegrin protein; metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15; metargidin; tMDC VI; tMDCVI

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
8751

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG

Img

Thermo Scientific

PIMA540912

--


Antigen:
ADAM15

Classification:
Recombinant Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 0.5% BSA and 0.09% sodium azide

Gene Accession No.:
Q13444

Gene Symbols:
Adam15

Immunogen:
Recombinant Human ADAM15 protein

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry

Clone:
007

Conjugate:
PE

Gene:
Adam15

Gene Alias:
a disintegrin and metallopeptidase domain 15 (metargidin); a disintegrin and metalloprotease domain 15 (metargidin); a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 15; a disintegrin and metalloproteinase domain 15 (metargidin); AD56; ADAM; ADAM 15; ADAM metallopeptidase domain 15; Adam15; ADAMs; CRII-7; disintegrin and metalloprotease 15; disintegrin and metalloproteinase domain-containing protein 15; Mdc15; MDC-15; metalloendopeptidases; Metalloprotease RGD disintegrin protein; metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15; metargidin; tMDC VI; tMDCVI

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
8751

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG