PIMA540917
BACE1 Recombinant Rabbit Monoclonal Antibody (027), PE, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA540917-Each-of-1 | In Stock | ₹ 42,309.42 |
PIMA540917 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,309.42
GST (18%): ₹ 7,615.696
Total Price: ₹ 49,925.116
Antigen
BACE1
Classification
Recombinant Monoclonal
Concentration
0.1 mg/mL
Formulation
PBS with 0.5% BSA and 0.1% sodium azide
Gene Accession No.
P56817
Gene Symbols
BACE1
Immunogen
Recombinant Human BACE1/ASP2 protein
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Flow Cytometry
Clone
027
Conjugate
PE
Gene
BACE1
Gene Alias
APP beta-secretase; asp 2; ASP2; Aspartyl protease 2; BACE; BACE 1; BACE1; BACE-1D; BACE-I-432; Beta secretase; Beta-secretase 1; beta-secretase 1 precursor variant 1; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; beta-site APP-cleaving enzyme 1; C76936; HSPC104; hypothetical protein LOC403005; KIAA1149; Memapsin; Memapsin2; Memapsin-2; membrane-associated aspartic protease 2; protease; transmembrane aspartic proteinase Asp2; zgc:77409
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
23621
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Isotype
IgG
Related Products
Description
- May be stored for twelve months without detectable loss of activity
- Protect from prolonged exposure to light and do not freeze
- Sodium azide is toxic to cells and should be disposed of properly so flush with large volumes of water during disposal
- BACE1 (beta-secretase) is a key enzyme involved in the production of amyloid beta-peptides (Abeta) found in extracellular amyloid plaques of Alzheimer's disease (AD)
- In some cases early onset familial AD can be attributed to a "Swedish" mutation in the amyloid precursor protein (APP), which dramatically enhances the cleavage of this protein by BACE1
- This and other genetic and pathological evidence has led to therapeutic approaches that have focused on the inhibition of BACE1 and other APP-cleaving enzymes, such as gamma-secretase stuff
- APP is first cleaved by b-secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99)
- The C99 fragment serves as substrate for g-secretase to generate the 4 kDa amyloid-b peptide, which is deposited in the brains of all sufferers of Alzheimer's disease
- The long-sought b-secretase was recently identified by several groups independently and designated beta-site APP cleaving enzyme (BACE) and aspartyl protease 2 (Asp2)
- bACE/Asp2 is a novel transmembrane aspartic protease and colocalizes with APP.
Compare Similar Items
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Antigen: BACE1
Classification: Recombinant Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 0.5% BSA and 0.1% sodium azide
Gene Accession No.: P56817
Gene Symbols: BACE1
Immunogen: Recombinant Human BACE1/ASP2 protein
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Flow Cytometry
Clone: 027
Conjugate: PE
Gene: BACE1
Gene Alias: APP beta-secretase; asp 2; ASP2; Aspartyl protease 2; BACE; BACE 1; BACE1; BACE-1D; BACE-I-432; Beta secretase; Beta-secretase 1; beta-secretase 1 precursor variant 1; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; beta-site APP-cleaving enzyme 1; C76936; HSPC104; hypothetical protein LOC403005; KIAA1149; Memapsin; Memapsin2; Memapsin-2; membrane-associated aspartic protease 2; protease; transmembrane aspartic proteinase Asp2; zgc:77409
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 23621
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Isotype: IgG
Antigen:
BACE1
Classification:
Recombinant Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 0.5% BSA and 0.1% sodium azide
Gene Accession No.:
P56817
Gene Symbols:
BACE1
Immunogen:
Recombinant Human BACE1/ASP2 protein
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry
Clone:
027
Conjugate:
PE
Gene:
BACE1
Gene Alias:
APP beta-secretase; asp 2; ASP2; Aspartyl protease 2; BACE; BACE 1; BACE1; BACE-1D; BACE-I-432; Beta secretase; Beta-secretase 1; beta-secretase 1 precursor variant 1; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; beta-site APP-cleaving enzyme 1; C76936; HSPC104; hypothetical protein LOC403005; KIAA1149; Memapsin; Memapsin2; Memapsin-2; membrane-associated aspartic protease 2; protease; transmembrane aspartic proteinase Asp2; zgc:77409
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
23621
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Isotype:
IgG
Antigen: CAR
Classification: Recombinant Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 0.5% BSA and 0.03% ProClin 300
Gene Accession No.: P78310
Gene Symbols: CXADR
Immunogen: Recombinant Human CXADR/CAR protein
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Flow Cytometry
Clone: 271
Conjugate: FITC
Gene: CXADR
Gene Alias: 2610206D03Rik; 46 kD coxsackievirus and adenovirus receptor (CAR) protein; AU016810; AW553441; CAR; Car1; CAR4/6; coxsackie virus and adenovirus receptor; coxsackievirus and adenovirus receptor; Coxsackievirus and adenovirus receptor homolog; coxsackievirus B-adenovirus receptor; CVB3-binding protein; Cxadr; HCAR; HCVADR; MCAR; MCVADR; rCAR
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1525
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Isotype: IgG
Antigen:
CAR
Classification:
Recombinant Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 0.5% BSA and 0.03% ProClin 300
Gene Accession No.:
P78310
Gene Symbols:
CXADR
Immunogen:
Recombinant Human CXADR/CAR protein
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry
Clone:
271
Conjugate:
FITC
Gene:
CXADR
Gene Alias:
2610206D03Rik; 46 kD coxsackievirus and adenovirus receptor (CAR) protein; AU016810; AW553441; CAR; Car1; CAR4/6; coxsackie virus and adenovirus receptor; coxsackievirus and adenovirus receptor; Coxsackievirus and adenovirus receptor homolog; coxsackievirus B-adenovirus receptor; CVB3-binding protein; Cxadr; HCAR; HCVADR; MCAR; MCVADR; rCAR
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1525
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Isotype:
IgG
Antigen: CAR
Classification: Recombinant Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 0.5% BSA and 0.03% ProClin 300
Gene Accession No.: P78310
Gene Symbols: CXADR
Immunogen: Recombinant Human CXADR/CAR protein
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Flow Cytometry
Clone: 271
Conjugate: PE
Gene: CXADR
Gene Alias: 2610206D03Rik; 46 kD coxsackievirus and adenovirus receptor (CAR) protein; AU016810; AW553441; CAR; Car1; CAR4/6; coxsackie virus and adenovirus receptor; coxsackievirus and adenovirus receptor; Coxsackievirus and adenovirus receptor homolog; coxsackievirus B-adenovirus receptor; CVB3-binding protein; Cxadr; HCAR; HCVADR; MCAR; MCVADR; rCAR
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1525
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Isotype: IgG
Antigen:
CAR
Classification:
Recombinant Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 0.5% BSA and 0.03% ProClin 300
Gene Accession No.:
P78310
Gene Symbols:
CXADR
Immunogen:
Recombinant Human CXADR/CAR protein
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry
Clone:
271
Conjugate:
PE
Gene:
CXADR
Gene Alias:
2610206D03Rik; 46 kD coxsackievirus and adenovirus receptor (CAR) protein; AU016810; AW553441; CAR; Car1; CAR4/6; coxsackie virus and adenovirus receptor; coxsackievirus and adenovirus receptor; Coxsackievirus and adenovirus receptor homolog; coxsackievirus B-adenovirus receptor; CVB3-binding protein; Cxadr; HCAR; HCVADR; MCAR; MCVADR; rCAR
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1525
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Isotype:
IgG
Antigen: CD16
Classification: Recombinant Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 0.5% BSA and 0.03% ProClin 300
Gene Accession No.: A0A0B4J1G0, P08508
Gene Symbols: Fcgr3, Fcgr4
Immunogen: Recombinant Mouse CD16/FCGR3 protein
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Mouse
Form: Liquid
Applications: Flow Cytometry
Clone: 002
Conjugate: APC
Gene: Fcgr3
Gene Alias: 4833442P21Rik; CD16; CD16-2; CD16A; CD16a antigen; CD16b; CD32; CD32 receptor 2; CDw32; cytolytic trigger molecule G7; Fc fragment of IgG intermediate affinity IV receptor; Fc fragment of IgG low affinity IIIa receptor; Fc fragment of IgG receptor IIIa; Fc fragment of IgG receptor IIIb; Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor; Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc gamma receptor III; Fc gamma receptor IIIa; Fc gamma receptor III-A; Fc gamma receptor IIIb; Fc gamma RIIIa; Fc gammaRIV; Fc receptor, IgG, low affinity III; Fc receptor, IgG, low affinity IV; Fc receptor-like 3; Fcg receptor III; FCG2; FCG3; Fc-gamma receptor III-2 (CD 16); Fc-gamma receptor IIIb (CD 16); Fc-gamma receptor IIIb (CD16); Fc-gamma RII-b; Fc-gamma RII-c; fc-gamma RIII; Fc-gamma RIIIa; Fc-gamma RIII-alpha; fc-gamma RIIIb; fc-gamma RIII-beta; Fc-gamma-RIIb; Fc-gamma-RIIc; FcgammaRIII; FcgammaRIII a.1; FcgammaRIII a.2; FcgammaRIII a.3; FcgammaRIIIA; FcgammaRIV; FCGR2; FCGR2A; FCGR2B; FCGR2C; FCGR3; Fcgr3a; FCGR3B; Fcgr4; FCGRIII; FcgRIV; FcR-10; FcRII-b; FcRII-c; FcRIII; FCRIIIA; FCRIIIb; Fcrl3; IGFR3; IgG Fc gamma receptor III; igG Fc receptor III; IgG Fc receptor III-1; igG Fc receptor III-2; IMD20; immunoglobulin G Fc receptor III; LOC100911825; Low affinity immunoglobulin gamma Fc region receptor III; low affinity immunoglobulin gamma Fc region receptor III-A; Low affinity immunoglobulin gamma Fc region receptor III-B; low affinity immunoglobulin gamma Fc region receptor III-like; Low affinity immunoglobulin gamma Fc region receptor IV; neutrophil-specific antigen NA; RP11-5K23.1; transmembrane receptor FcgammaRIII-X
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 14131, 246256
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Isotype: IgG
Antigen:
CD16
Classification:
Recombinant Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 0.5% BSA and 0.03% ProClin 300
Gene Accession No.:
A0A0B4J1G0, P08508
Gene Symbols:
Fcgr3, Fcgr4
Immunogen:
Recombinant Mouse CD16/FCGR3 protein
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Liquid
Applications:
Flow Cytometry
Clone:
002
Conjugate:
APC
Gene:
Fcgr3
Gene Alias:
4833442P21Rik; CD16; CD16-2; CD16A; CD16a antigen; CD16b; CD32; CD32 receptor 2; CDw32; cytolytic trigger molecule G7; Fc fragment of IgG intermediate affinity IV receptor; Fc fragment of IgG low affinity IIIa receptor; Fc fragment of IgG receptor IIIa; Fc fragment of IgG receptor IIIb; Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor; Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc gamma receptor III; Fc gamma receptor IIIa; Fc gamma receptor III-A; Fc gamma receptor IIIb; Fc gamma RIIIa; Fc gammaRIV; Fc receptor, IgG, low affinity III; Fc receptor, IgG, low affinity IV; Fc receptor-like 3; Fcg receptor III; FCG2; FCG3; Fc-gamma receptor III-2 (CD 16); Fc-gamma receptor IIIb (CD 16); Fc-gamma receptor IIIb (CD16); Fc-gamma RII-b; Fc-gamma RII-c; fc-gamma RIII; Fc-gamma RIIIa; Fc-gamma RIII-alpha; fc-gamma RIIIb; fc-gamma RIII-beta; Fc-gamma-RIIb; Fc-gamma-RIIc; FcgammaRIII; FcgammaRIII a.1; FcgammaRIII a.2; FcgammaRIII a.3; FcgammaRIIIA; FcgammaRIV; FCGR2; FCGR2A; FCGR2B; FCGR2C; FCGR3; Fcgr3a; FCGR3B; Fcgr4; FCGRIII; FcgRIV; FcR-10; FcRII-b; FcRII-c; FcRIII; FCRIIIA; FCRIIIb; Fcrl3; IGFR3; IgG Fc gamma receptor III; igG Fc receptor III; IgG Fc receptor III-1; igG Fc receptor III-2; IMD20; immunoglobulin G Fc receptor III; LOC100911825; Low affinity immunoglobulin gamma Fc region receptor III; low affinity immunoglobulin gamma Fc region receptor III-A; Low affinity immunoglobulin gamma Fc region receptor III-B; low affinity immunoglobulin gamma Fc region receptor III-like; Low affinity immunoglobulin gamma Fc region receptor IV; neutrophil-specific antigen NA; RP11-5K23.1; transmembrane receptor FcgammaRIII-X
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
14131, 246256
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Isotype:
IgG