PIMA541110

STAT3 Recombinant Rabbit Monoclonal Antibody (SY34-01), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA541110-Each-of-1 In Stock ₹ 44,961.78

PIMA541110 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

STAT3

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P40763, P42227, P52631

Gene Symbols

STAT3

Immunogen

Synthetic peptide within C-terminal human STAT3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

SY34-01

Conjugate

Unconjugated

Gene

STAT3

Gene Alias

1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

20848, 25125, 6774

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • STAT3 belongs to the family of STAT (signal transducers and activators of transcription) proteins which are phosphorylated by receptor associated kinases, translocate to the nucleus, and act as transcription factors in response to cytokines and growth factors
  • Coactivators such as CREB-binding protein are required for the transcriptional activation by STAT3
  • STAT3 can also be activated by Interferon-alpha, Interferon-gamma, EGF, PDGF and IL6
  • Phosphorylation on tyrosine 705 by JAK1 and JAK2 is essential for STAT3 dimer formation, nuclear translocation, and DNA binding activity
  • In humans, the STAT3 gene is located on the q arm of chromosome 17
  • STAT3 has been shown to be activated by IFN-alpha but not IFN-beta
  • The transcription factors associated with STAT3 are c-Jun and cyclic AMP-responsive enhancer binding protein (CREB)
  • STAT3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis
  • The small GTPase Rac1 has been shown to bind and regulate the activity of STAT3 while the PIAS3 protein is a specific inhibitor of STAT3
  • Three alternatively spliced transcript variants encoding distinct isoforms of STAT3 have been described
  • Deletion of the STAT3 gene in knock-out mice was lethal at the early embryonic stage.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA541110

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Antigen:
STAT3

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P40763, P42227, P52631

Gene Symbols:
STAT3

Immunogen:
Synthetic peptide within C-terminal human STAT3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
SY34-01

Conjugate:
Unconjugated

Gene:
STAT3

Gene Alias:
1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20848, 25125, 6774

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA541111

--


Antigen:
STAT1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P42224, P42225

Gene Symbols:
STAT1

Immunogen:
Synthetic peptide within human STAT1 aa 710-750

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Western Blot

Clone:
SJ01-89

Conjugate:
Unconjugated

Gene:
STAT1

Gene Alias:
2010005J02Rik; AA408197; CANDF7; DD6G4-4; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF-3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta; OTTHUMP00000165046; OTTHUMP00000205845; signal transducer and activator of transcription 1; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1-alpha/beta; signal transducer and activator of transcription-1; STAT; STAT 1; STAT1; STAT-1; stat1 alpha; STAT91; transcription factor ISGF-3; transcription factor ISGF-3 components p91/p84

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20846, 6772

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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PIMA541113

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Antigen:
c-Met

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P08581

Gene Symbols:
MET

Immunogen:
Synthetic peptide within C-terminal human Met

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
SJ19-05

Conjugate:
Unconjugated

Gene:
MET

Gene Alias:
AI838057; AUTS9; bHLHe59; CG1705; CG1705-PA; CG1705-PB; cmet; c-met; c-met proto-oncogene; c-Met receptor tyrosine kinase; c-Met/HGF receptor; D249; DFNB97; Dmel\CG1705; Dmel_CG1705; DmMet; EC 2.7.10.1; Hepatocyte growth factor receptor; HGF; HGF receptor; HGF receptor c-Met; HGF/SF receptor; HGFR; HGF-SF receptor; juvenile hormone resistance; met; met proto-oncogene; met proto-oncogene (hepatocyte growth factor receptor); met proto-oncogene tyrosine kinase; MET proto-oncogene, receptor tyrosine kinase; Met/Met1; Met; protein tyrosin kinase; methoprene tolerant; Methoprene-tolerant; Methoprene-tolerant protein; Met-PA; Met-PB; Mett; oncogene MET; Par4; Proto-oncogene c-Met; RCCP2; resistance (1) juvenile H; resistance to juvenile hormone; Rst(1)JH; sc MET; scatter factor receptor; SF receptor; soluble c met; tyrosine-protein kinase Met

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4233

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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PIMA541115

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Antigen:
Synaptophysin

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P07825, P08247, Q62277

Gene Symbols:
Syp

Immunogen:
recombinant protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
SJ26-85

Conjugate:
Unconjugated

Gene:
Syp

Gene Alias:
A230093K24Rik; AI848995; BM89 antigen; I79_012252; Major synaptic vesicle protein p38; MRX96; MRXSYP; p38; Syn; Synaptophysin; Syp; Syp I; Syp1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20977, 24804, 6855

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid