PIMA541660

PEDF Monoclonal Antibody (C3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA541660-Each-of-1 In Stock ₹ 44,020.62

PIMA541660 - Each of 1

₹ 44,020.62

In Stock

Quantity

1

Base Price: ₹ 44,020.62

GST (18%): ₹ 7,923.712

Total Price: ₹ 51,944.332

Antigen

PEDF

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

P97298

Gene Symbols

SERPINF1

Immunogen

Recombinant protein Pigment Epithelium Derived Factor. The antigen corresponds to amino acid range 19-417 of the target protein.

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2b κ

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

C3

Conjugate

Unconjugated

Gene

SERPINF1

Gene Alias

AI195227; alpha-2 antiplasmin; caspin; Cell proliferation-inducing gene 35 protein; Dmrs91; EPC 1; EPC1; EPC-1; OI12; OI6; PEDF; Pedfl; PIG 35; PIG35; pigment epithelium derived factor; pigment epithelium-derived factor; Sdf3; SDF-3; serine (or cysteine) peptidase inhibitor, clade F, member 1; serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; serine (or cysteine) proteinase inhibitor, clade F), member 1; serine (or cysteine) proteinase inhibitor, clade F, member 1; serpin F1; serpin family F member 1; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; serpin peptidase inhibitor, clade F, member 1; SERPINF 1; Serpinf1; serpin-F1; sserpin family F member 1; stromal cell derived factor 3; stromal cell-derived factor 3; testis tissue sperm-binding protein Li 70n

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

20317

Content And Storage

-20°C

Form

Liquid

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Description

  • PEDF is a noninhibitory serpin with neurotrophic, anti-angiogenic, and anti-tumorigenic properties
  • It is a 50 kDa glycoprotein produced and secreted in many tissues throughout the body
  • A major component of the anti-angiogenic action of PEDF is the induction of apoptosis in proliferating endothelial cells
  • In addition, PEDF is able to inhibit the activity of angiogenic factors, such as VEGF and FGF-2
  • The neuroprotective effects of PEDF are achieved through suppression of neuronal apoptosis induced by peroxide, glutamate, or other neurotoxins
  • The recent identification of a lipase-linked cell membrane receptor for PEDF (PEDF-R) that binds to PEDF with high affinity (1) should facilitate further elucidation of the underlying mechanisms of this pluripotent serpin
  • To date, PEDF-R is the only signaling receptor known to be used by a serpin family member
  • The unique range of PEDF activities implicate it as a potential therapeutic agent for the treatment of vasculature-related neurodegenerative diseases, such as age-related macular degeneration (AMD) and proliferative diabetic retinopathy (PDR)
  • PEDF also has the potential to be useful in the treatment of various angiogenesis-related diseases including a number of cancers.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA541660

--


Antigen:
PEDF

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P97298

Gene Symbols:
SERPINF1

Immunogen:
Recombinant protein Pigment Epithelium Derived Factor. The antigen corresponds to amino acid range 19-417 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C3

Conjugate:
Unconjugated

Gene:
SERPINF1

Gene Alias:
AI195227; alpha-2 antiplasmin; caspin; Cell proliferation-inducing gene 35 protein; Dmrs91; EPC 1; EPC1; EPC-1; OI12; OI6; PEDF; Pedfl; PIG 35; PIG35; pigment epithelium derived factor; pigment epithelium-derived factor; Sdf3; SDF-3; serine (or cysteine) peptidase inhibitor, clade F, member 1; serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; serine (or cysteine) proteinase inhibitor, clade F), member 1; serine (or cysteine) proteinase inhibitor, clade F, member 1; serpin F1; serpin family F member 1; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; serpin peptidase inhibitor, clade F, member 1; SERPINF 1; Serpinf1; serpin-F1; sserpin family F member 1; stromal cell derived factor 3; stromal cell-derived factor 3; testis tissue sperm-binding protein Li 70n

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
20317

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA541663

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Antigen:
P3NP

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P02461

Gene Symbols:
COL3A1

Immunogen:
Recombinant protein Procollagen III N-Terminal Propeptide

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Western Blot

Clone:
J38

Conjugate:
Unconjugated

Gene:
COL3A1

Gene Alias:
PIIINP gene; Procollagen 3 N-Terminal Propeptide; Procollagen III N-Terminal Propeptide

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
1281

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA541665

--


Antigen:
REG3G

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q6UW15

Gene Symbols:
REG3G

Immunogen:
Recombinant protein Regenerating Islet Derived Protein 3 Gamma. The antigen corresponds to amino acid range 39-175 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C18

Conjugate:
Unconjugated

Gene:
REG3G

Gene Alias:
AI449515; generating islet-derived, mouse homolog 3 gamma; LPPM429; Pancreatitis-associated protein 1B; pancreatitis-associated protein 3; Pancreatitis-associated protein IB; PAP IB; PAP1B; PAP-1B; Pap3; PAPIB; PAPIII; REG III; Reg III-gamma; REG3G; REG3gamma; REG-3gamma; REG-3-gamma; regenerating family member 3 gamma; regenerating gene III; regenerating islet-derived 3 gamma; regenerating islet-derived protein 3 gamma; regenerating islet-derived protein 3-gamma; Regenerating islet-derived protein 3-gamma 15 kDa form; Regenerating islet-derived protein 3-gamma 16.5 kDa form; Regenerating islet-derived protein III-gamma; REG-III; RegIII (gamma); UNQ429; UNQ429/PRO162

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
130120

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA541666

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Antigen:
REG3G

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q6UW15

Gene Symbols:
REG3G

Immunogen:
Recombinant protein Regenerating Islet Derived Protein 3 Gamma. The antigen corresponds to amino acid range 39-175 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
D9

Conjugate:
Unconjugated

Gene:
REG3G

Gene Alias:
AI449515; generating islet-derived, mouse homolog 3 gamma; LPPM429; Pancreatitis-associated protein 1B; pancreatitis-associated protein 3; Pancreatitis-associated protein IB; PAP IB; PAP1B; PAP-1B; Pap3; PAPIB; PAPIII; REG III; Reg III-gamma; REG3G; REG3gamma; REG-3gamma; REG-3-gamma; regenerating family member 3 gamma; regenerating gene III; regenerating islet-derived 3 gamma; regenerating islet-derived protein 3 gamma; regenerating islet-derived protein 3-gamma; Regenerating islet-derived protein 3-gamma 15 kDa form; Regenerating islet-derived protein 3-gamma 16.5 kDa form; Regenerating islet-derived protein III-gamma; REG-III; RegIII (gamma); UNQ429; UNQ429/PRO162

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
130120

Content And Storage:
-20°C

Form:
Liquid