PIMA542380
SARM Recombinant Rabbit Monoclonal Antibody (HL1070), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA542380-Each-of-1 | In Stock | ₹ 44,020.62 |
PIMA542380 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,020.62
GST (18%): ₹ 7,923.712
Total Price: ₹ 51,944.332
Antigen
SARM
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
Q6PDS3, Q6SZW1
Gene Symbols
SARM1
Immunogen
Recombinant protein encompassing a sequence within the center region of human SARM1. The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Clone
HL1070
Conjugate
Unconjugated
Gene
SARM1
Gene Alias
A830091I15Rik; C78606; FLJ36296; KIAA0524; MyD885; MyD88-5; SAM domain-containing protein 2; SAMD2; SARM; SARM1; Sterile alpha and Armadillo repeat protein; sterile alpha and HEAT/Armadillo motif containing 1; sterile alpha and HEAT/Armadillo motif protein, ortholog of Drosophila; sterile alpha and TIR motif containing 1; sterile alpha and TIR motif-containing protein 1; Sterile alpha motif domain-containing protein 2; tir-1 homolog
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
23098, 237868, 287545
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Store as concentrated solution
- Centrifuge briefly prior to opening vial
- For short-term storage (1-2 weeks), store at 4°C
- For long-term storage, aliquot and store at -20°C or below
- Avoid multiple freeze-thaw cycles
- NAD(+) hydrolase, which plays a key role in axonal degeneration following injury by regulating NAD(+) metabolism (PubMed:25908823, PubMed:27671644, PubMed:28334607)
- Acts as a negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway by promoting Wallerian degeneration, an injury-induced form of programmed subcellular death which involves degeneration of an axon distal to the injury site (PubMed:15123841, PubMed:16964262, PubMed:20306472, PubMed:25908823)
- Wallerian degeneration is triggered by NAD(+) depletion: in response to injury, SARM1 is activated and catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR), cyclic ADPR (cADPR) and nicotinamide; NAD(+) cleavage promoting cytoskeletal degradation and axon destruction (PubMed:25908823, PubMed:28334607, PubMed:30333228, PubMed:31128467, PubMed:31439793, PubMed:31439792)
- Also able to hydrolyze NADP(+), but not other NAD(+)-related molecules (PubMed:29395922)
- Can activate neuronal cell death in response to stress (PubMed:20306472)
- Regulates dendritic arborization through the MAPK4-JNK pathway
- Involved in innate immune response: inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38 (PubMed:16964262)
- [UniProt]
Compare Similar Items
Show Difference
Antigen: SARM
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q6PDS3, Q6SZW1
Gene Symbols: SARM1
Immunogen: Recombinant protein encompassing a sequence within the center region of human SARM1. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: HL1070
Conjugate: Unconjugated
Gene: SARM1
Gene Alias: A830091I15Rik; C78606; FLJ36296; KIAA0524; MyD885; MyD88-5; SAM domain-containing protein 2; SAMD2; SARM; SARM1; Sterile alpha and Armadillo repeat protein; sterile alpha and HEAT/Armadillo motif containing 1; sterile alpha and HEAT/Armadillo motif protein, ortholog of Drosophila; sterile alpha and TIR motif containing 1; sterile alpha and TIR motif-containing protein 1; Sterile alpha motif domain-containing protein 2; tir-1 homolog
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 23098, 237868, 287545
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
SARM
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q6PDS3, Q6SZW1
Gene Symbols:
SARM1
Immunogen:
Recombinant protein encompassing a sequence within the center region of human SARM1. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
HL1070
Conjugate:
Unconjugated
Gene:
SARM1
Gene Alias:
A830091I15Rik; C78606; FLJ36296; KIAA0524; MyD885; MyD88-5; SAM domain-containing protein 2; SAMD2; SARM; SARM1; Sterile alpha and Armadillo repeat protein; sterile alpha and HEAT/Armadillo motif containing 1; sterile alpha and HEAT/Armadillo motif protein, ortholog of Drosophila; sterile alpha and TIR motif containing 1; sterile alpha and TIR motif-containing protein 1; Sterile alpha motif domain-containing protein 2; tir-1 homolog
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
23098, 237868, 287545
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: SARS-CoV-2 Spike Protein (RBD)
Classification: Recombinant Monoclonal
Concentration: 0.83 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: __
Gene Symbols: __
Immunogen: Recombinant protein corresponding to SARS-CoV-2 (COVID-19) Spike RBD (SARS-CoV-2 (strain Wuhan-Hu-1). The exact sequence is proprietary.
Quantity: 50 μL
Primary or Secondary: Primary
Target Species: Virus
Product Type: Antibody
Isotype: IgG
Applications: ELISA
Clone: HL1003
Conjugate: HRP
Gene: __
Gene Alias: Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
SARS-CoV-2 Spike Protein (RBD)
Classification:
Recombinant Monoclonal
Concentration:
0.83 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Recombinant protein corresponding to SARS-CoV-2 (COVID-19) Spike RBD (SARS-CoV-2 (strain Wuhan-Hu-1). The exact sequence is proprietary.
Quantity:
50 μL
Primary or Secondary:
Primary
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA
Clone:
HL1003
Conjugate:
HRP
Gene:
__
Gene Alias:
Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: SARS-CoV-2 Spike Protein (RBD)
Classification: Recombinant Monoclonal
Concentration: 0.83 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: __
Gene Symbols: __
Immunogen: Recombinant protein corresponding to SARS-CoV-2 Spike RBD.
Quantity: 50 μL
Primary or Secondary: Primary
Target Species: Virus
Product Type: Antibody
Isotype: IgG
Applications: ELISA
Clone: HL1004
Conjugate: HRP
Gene: __
Gene Alias: Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
SARS-CoV-2 Spike Protein (RBD)
Classification:
Recombinant Monoclonal
Concentration:
0.83 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Recombinant protein corresponding to SARS-CoV-2 Spike RBD.
Quantity:
50 μL
Primary or Secondary:
Primary
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA
Clone:
HL1004
Conjugate:
HRP
Gene:
__
Gene Alias:
Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: SARS-CoV-2 Spike Protein S2
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: __
Gene Symbols: __
Immunogen: Full length SARS-CoV-2 (COVID-19) Spike RBD recombinant protein (strain Wuhan-Hu-1).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Virus
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: HL1039
Conjugate: Unconjugated
Gene: __
Gene Alias: Coronavirus, COVID, Covid 19, COVID19, COVID-19, COVID-19 S2, COVID19 Spike S2, SARS, SARS Coronavirus, SARS CoV, SARS CoV2, SARS CoV-2, SARS Spike Protein, SARS-CoV2, SARS-CoV-2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
SARS-CoV-2 Spike Protein S2
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Full length SARS-CoV-2 (COVID-19) Spike RBD recombinant protein (strain Wuhan-Hu-1).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
HL1039
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
Coronavirus, COVID, Covid 19, COVID19, COVID-19, COVID-19 S2, COVID19 Spike S2, SARS, SARS Coronavirus, SARS CoV, SARS CoV2, SARS CoV-2, SARS Spike Protein, SARS-CoV2, SARS-CoV-2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid