PIMA542425
JAK2 Recombinant Rabbit Monoclonal Antibody (SY0245), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA542425-Each-of-1 | In Stock | ₹ 44,020.62 |
PIMA542425 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,020.62
GST (18%): ₹ 7,923.712
Total Price: ₹ 51,944.332
Antigen
JAK2
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
O60674, Q62120, Q62689
Gene Symbols
JAK2
Immunogen
Synthetic peptide within C-terminal human JAK2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Clone
SY0245
Conjugate
Unconjugated
Gene
JAK2
Gene Alias
EC 2.7.10.2; Fd17; JAK 2; JAK2; JAK-2; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); JTK 10; JTK10; kinase Jak2; THCYT3; Tyrosine-protein kinase JAK2
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
16452, 24514, 3717
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Positive Control: A549 cell lysate, MCF-7 cell lysate, A549, MCF-7, NIH/3T3
- Subcellular Location: Endomembrane system, Cytoplasm, Nucleus
- Janus kinase 2 (JAK2) is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera
- This kinase contains the catalytic domain (JH1) of JAK2
- The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
- Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
- JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
- Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex
- Mutations affecting JAK2 can cause Budd-Chiari syndrome, Polycythemia vera, Thrombocythemia 3, myelofibrosis, or Acute myelogenous leukemia.
Compare Similar Items
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Antigen: JAK2
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: O60674, Q62120, Q62689
Gene Symbols: JAK2
Immunogen: Synthetic peptide within C-terminal human JAK2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: SY0245
Conjugate: Unconjugated
Gene: JAK2
Gene Alias: EC 2.7.10.2; Fd17; JAK 2; JAK2; JAK-2; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); JTK 10; JTK10; kinase Jak2; THCYT3; Tyrosine-protein kinase JAK2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 16452, 24514, 3717
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
JAK2
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
O60674, Q62120, Q62689
Gene Symbols:
JAK2
Immunogen:
Synthetic peptide within C-terminal human JAK2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
SY0245
Conjugate:
Unconjugated
Gene:
JAK2
Gene Alias:
EC 2.7.10.2; Fd17; JAK 2; JAK2; JAK-2; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); JTK 10; JTK10; kinase Jak2; THCYT3; Tyrosine-protein kinase JAK2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
16452, 24514, 3717
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: SMAD1
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P70340, Q15797
Gene Symbols: SMAD1
Immunogen: Synthetic peptide within human Smad1 aa 150-200
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: SY0254
Conjugate: Unconjugated
Gene: SMAD1
Gene Alias: AI528653; BSP1; BSP-1; dwarfin-A; Dwf-A; DWFC; hSMAD1; JV41; JV4-1; JV5-1; MAD (mothers against decapentaplegic, Drosophila) homolog 1; MAD homolog 1; MAD homolog1 (mothers against decapentaplegic, Drosophila); MAD, mothers against decapentaplegic homolog 1; Madh1; MADH5; MADR1; Mad-related protein 1; Mlp1; mMad1; mothers against decapentaplegic homolog 1; mothers against DPP homolog 1; mothers-against-DPP-related 1; Mothers-against-DPP-related-1; MusMLP; OTTHUMP00000220456; SMAD; Smad 1; SMAD family member 1; SMAD, mothers against DPP homolog 1; Smad1; SMAD5; TGF-beta signaling protein 1; transforming growth factor-beta signaling protein 1; Transforming growth factor-beta-signaling protein 1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 17125, 4086
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
SMAD1
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P70340, Q15797
Gene Symbols:
SMAD1
Immunogen:
Synthetic peptide within human Smad1 aa 150-200
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
SY0254
Conjugate:
Unconjugated
Gene:
SMAD1
Gene Alias:
AI528653; BSP1; BSP-1; dwarfin-A; Dwf-A; DWFC; hSMAD1; JV41; JV4-1; JV5-1; MAD (mothers against decapentaplegic, Drosophila) homolog 1; MAD homolog 1; MAD homolog1 (mothers against decapentaplegic, Drosophila); MAD, mothers against decapentaplegic homolog 1; Madh1; MADH5; MADR1; Mad-related protein 1; Mlp1; mMad1; mothers against decapentaplegic homolog 1; mothers against DPP homolog 1; mothers-against-DPP-related 1; Mothers-against-DPP-related-1; MusMLP; OTTHUMP00000220456; SMAD; Smad 1; SMAD family member 1; SMAD, mothers against DPP homolog 1; Smad1; SMAD5; TGF-beta signaling protein 1; transforming growth factor-beta signaling protein 1; Transforming growth factor-beta-signaling protein 1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
17125, 4086
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Phospho-GSK3 alpha/beta (Tyr216, Tyr279)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P18265, P18266, P49840, P49841, Q2NL51, Q9WV60
Gene Symbols: GSK3A, GSK3B
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Tyr216 and 279 of human GSK3(alpha+beta)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: SY26-05
Conjugate: Unconjugated
Gene: GSK3A
Gene Alias: 2700086H06Rik; 7330414F15Rik; 8430431H08Rik; C86142; FA; factor A; glycogen synthase kinase 3 alpha; glycogen synthase kinase 3 beta; glycogen synthase kinase-3 alpha; Glycogen synthase kinase-3 beta; GSK3; GSK-3; GSK-3 alpha; GSK-3 beta; Gsk3a; gsk-3-alpha; Gsk3b; GSK-3beta; GSK3beta isoform; serine/threonine-protein kinase GSK3A; Serine/threonine-protein kinase GSK3B
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2931, 2932, 50686, 56637, 606496, 84027
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Phospho-GSK3 alpha/beta (Tyr216, Tyr279)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P18265, P18266, P49840, P49841, Q2NL51, Q9WV60
Gene Symbols:
GSK3A, GSK3B
Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Tyr216 and 279 of human GSK3(alpha+beta)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
SY26-05
Conjugate:
Unconjugated
Gene:
GSK3A
Gene Alias:
2700086H06Rik; 7330414F15Rik; 8430431H08Rik; C86142; FA; factor A; glycogen synthase kinase 3 alpha; glycogen synthase kinase 3 beta; glycogen synthase kinase-3 alpha; Glycogen synthase kinase-3 beta; GSK3; GSK-3; GSK-3 alpha; GSK-3 beta; Gsk3a; gsk-3-alpha; Gsk3b; GSK-3beta; GSK3beta isoform; serine/threonine-protein kinase GSK3A; Serine/threonine-protein kinase GSK3B
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2931, 2932, 50686, 56637, 606496, 84027
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Phospho-IRF3 (Ser386)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q14653
Gene Symbols: IRF3
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Ser386 of human IRF3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: SU03-28
Conjugate: Unconjugated
Gene: IRF3
Gene Alias: C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3661
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Phospho-IRF3 (Ser386)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q14653
Gene Symbols:
IRF3
Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Ser386 of human IRF3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
SU03-28
Conjugate:
Unconjugated
Gene:
IRF3
Gene Alias:
C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3661
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid