PIMA542434
Phospho-IkB alpha (Ser32) Recombinant Rabbit Monoclonal Antibody (ST53-05), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA542434-Each-of-1 | In Stock | ₹ 44,020.62 |
PIMA542434 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,020.62
GST (18%): ₹ 7,923.712
Total Price: ₹ 51,944.332
Antigen
Phospho-IkB alpha (Ser32)
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P25963, Q9Z1E3
Gene Symbols
NFKBIA
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Ser32 of human IKB alpha
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
ST53-05
Conjugate
Unconjugated
Gene
NFKBIA
Gene Alias
AI462015; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; IkappaBalpha; I-kappaBalpha; I-kappa-B-alpha; Ikba; IKBalpha; IKB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF kappa B inhibitor alpha; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; Nfkbia; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
18035, 4792
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Positive Control: SK-Br-3 cell lysates, Hela
- Subcellular Location: Cytoplasm, Nucleus
- IkB-alpha is a 40 kDa protein that functions to inhibit NF- kappaB activity
- The inhibition occurs via protein-protein interaction between I kappaB proteins and NF- kappaB dimers in the cytosol
- The interaction of I kappa B-alpha with NF- kappaB masks the nuclear localization sequence of NF- kappaB, preventing NF- kappaB translocation to the nucleus
- A variety of stimuli can activate gene expression by liberating NF- kappaB through the degradation of I kappaB alpha
- These stimuli include the proinflammatory cytokines TNF- alpha and IL-1 beta, chemokines, PMA, growth factors, LPS, UV irradiation, viral infection, as well as various chemical and physical stresses
- In humans, the gene is located on the q arm of chromosome 14
- Activation of NFkB requires that IkB be phosphorylated on specific serine residues, which results in targeted degradation of IkB
- IkB kinase alpha (IKK alpha), previously designated CHUK, interacts with IkB-alpha and specifically phosphorylates IkB-alpha on the sites that trigger its degradation Serines 32 and 36
- IKK alpha appears to be critical for NFkB activation in response to proinflammatory cytokines
- Phosphorylation of IkB by IKK alpha is stimulated by the NFkB inducing kinase (NIK), which itself is a central regulator for NFkB activation in response to TNF and IL-1
- The functional IKK complex contains three subunits, IKK alpha, IKK beta and IKK gamma, and each appear to make essential contributions to IkB phosphorylation.
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Antigen: Phospho-IkB alpha (Ser32)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P25963, Q9Z1E3
Gene Symbols: NFKBIA
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Ser32 of human IKB alpha
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: ST53-05
Conjugate: Unconjugated
Gene: NFKBIA
Gene Alias: AI462015; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; IkappaBalpha; I-kappaBalpha; I-kappa-B-alpha; Ikba; IKBalpha; IKB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF kappa B inhibitor alpha; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; Nfkbia; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 18035, 4792
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Phospho-IkB alpha (Ser32)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P25963, Q9Z1E3
Gene Symbols:
NFKBIA
Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Ser32 of human IKB alpha
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
ST53-05
Conjugate:
Unconjugated
Gene:
NFKBIA
Gene Alias:
AI462015; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; IkappaBalpha; I-kappaBalpha; I-kappa-B-alpha; Ikba; IKBalpha; IKB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF kappa B inhibitor alpha; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; Nfkbia; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
18035, 4792
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: H3R2me1
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P68431, P68433, P84228, Q71DI3
Gene Symbols: H3C1, H3C10, H3C12, H3C14, H3C15, H3C2, H3C7
Immunogen: Synthetic peptide within human histone h3 aa 1-49
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: ST0427
Conjugate: Unconjugated
Gene: H3C15
Gene Alias: H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3C; H3 R2; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; H3.3A; H3.3B; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-53; H3-614; H3a; H3Arg2me; H3Arg2me1; H3b; H3-B; H3C1; H3c10; H3c11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3f; H3-F; H3F1K; H3F2; H3F3; H3F3A; H3F3B; H3F3C; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; H3g; H3h; H3i; H3R2; H3R2me; Hist1; Hist1h3a; HIST1H3B; Hist1h3c; HIST1H3D; Hist1h3e; Hist1h3f; HIST1H3G; Hist1h3h; HIST1H3I; HIST1H3J; HIST2H3A; Hist2h3b; HIST2H3C; Hist2h3c1; Hist2h3c2; Hist2h3c2-ps; Hist2h3ca1; Hist2h3ca2; HIST2H3D; histone 1, H3a; histone 1, H3b; histo
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 126961, 260423, 319150, 319152, 333932, 360198, 8350, 8356, 8357, 8358, 8968, 97114
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
H3R2me1
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P68431, P68433, P84228, Q71DI3
Gene Symbols:
H3C1, H3C10, H3C12, H3C14, H3C15, H3C2, H3C7
Immunogen:
Synthetic peptide within human histone h3 aa 1-49
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
ST0427
Conjugate:
Unconjugated
Gene:
H3C15
Gene Alias:
H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3C; H3 R2; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; H3.3A; H3.3B; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-53; H3-614; H3a; H3Arg2me; H3Arg2me1; H3b; H3-B; H3C1; H3c10; H3c11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3f; H3-F; H3F1K; H3F2; H3F3; H3F3A; H3F3B; H3F3C; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; H3g; H3h; H3i; H3R2; H3R2me; Hist1; Hist1h3a; HIST1H3B; Hist1h3c; HIST1H3D; Hist1h3e; Hist1h3f; HIST1H3G; Hist1h3h; HIST1H3I; HIST1H3J; HIST2H3A; Hist2h3b; HIST2H3C; Hist2h3c1; Hist2h3c2; Hist2h3c2-ps; Hist2h3ca1; Hist2h3ca2; HIST2H3D; histone 1, H3a; histone 1, H3b; histo
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
126961, 260423, 319150, 319152, 333932, 360198, 8350, 8356, 8357, 8358, 8968, 97114
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: NBS1
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: O60934, Q9JIL9, Q9R207
Gene Symbols: NBN
Immunogen: Synthetic peptide within human p95 NBS1 aa 680-730
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: SC05-68
Conjugate: Unconjugated
Gene: NBN
Gene Alias: AT V1; AT V2; ATV; AT-V1; AT-V2; Cell cycle regulatory protein p95; FLJ10155; I79_012607; MGC87362; Nbn; NBS; NBS1; nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome protein 1; Nijmegen breakage syndrome protein 1 homolog; OTTHUMP00000204088; P95; p95 protein of the MRE11/RAD50 complex; p95-NBS1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 27354, 4683, 85482
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
NBS1
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
O60934, Q9JIL9, Q9R207
Gene Symbols:
NBN
Immunogen:
Synthetic peptide within human p95 NBS1 aa 680-730
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
SC05-68
Conjugate:
Unconjugated
Gene:
NBN
Gene Alias:
AT V1; AT V2; ATV; AT-V1; AT-V2; Cell cycle regulatory protein p95; FLJ10155; I79_012607; MGC87362; Nbn; NBS; NBS1; nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome protein 1; Nijmegen breakage syndrome protein 1 homolog; OTTHUMP00000204088; P95; p95 protein of the MRE11/RAD50 complex; p95-NBS1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
27354, 4683, 85482
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Phospho-RSK1 (Ser380)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P18653, Q15418, Q63531
Gene Symbols: RPS6KA1
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding s380 of human rsk1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: SC05-32
Conjugate: Unconjugated
Gene: RPS6KA1
Gene Alias: 90 kDa ribosomal protein S6 kinase 1; dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1); hu-1; MAP kinase-activated protein kinase 1; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1; MAPK-activated protein kinase 1a; MAPKAP kinase 1; MAPKAP kinase 1a; MAPKAPK-1; mapkapk1a; MAPKAPK-1a; p90Rsk; P90-RSK; p90-RSK 1; p90Rsk1; p90-Rsk1; p90S6K; pp90RSK1; ribosomal protein S6 kinase 2 alpha; ribosomal protein S6 kinase 2 beta; ribosomal protein S6 kinase a, polypeptide 1; ribosomal protein S6 kinase A1; ribosomal protein S6 kinase A1 L homeolog; ribosomal protein S6 kinase alpha 1; Ribosomal protein S6 kinase alpha-1; Ribosomal protein S6 kinase II alpha; ribosomal protein S6 kinase II beta; ribosomal protein S6 kinase polypeptide 1; ribosomal protein S6 kinase, 90kD, polypeptide 1; Ribosomal protein S6 kinase, 90kD, 1; ribosomal protein S6 kinase, 90kDa, polypeptide 1; ribosomal protein S6 kinase, 90kDa, polypeptide 1 L homeolog; ribosomal protein S6 kinas
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 20111, 6195, 81771
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Phospho-RSK1 (Ser380)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P18653, Q15418, Q63531
Gene Symbols:
RPS6KA1
Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding s380 of human rsk1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
SC05-32
Conjugate:
Unconjugated
Gene:
RPS6KA1
Gene Alias:
90 kDa ribosomal protein S6 kinase 1; dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1); hu-1; MAP kinase-activated protein kinase 1; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1; MAPK-activated protein kinase 1a; MAPKAP kinase 1; MAPKAP kinase 1a; MAPKAPK-1; mapkapk1a; MAPKAPK-1a; p90Rsk; P90-RSK; p90-RSK 1; p90Rsk1; p90-Rsk1; p90S6K; pp90RSK1; ribosomal protein S6 kinase 2 alpha; ribosomal protein S6 kinase 2 beta; ribosomal protein S6 kinase a, polypeptide 1; ribosomal protein S6 kinase A1; ribosomal protein S6 kinase A1 L homeolog; ribosomal protein S6 kinase alpha 1; Ribosomal protein S6 kinase alpha-1; Ribosomal protein S6 kinase II alpha; ribosomal protein S6 kinase II beta; ribosomal protein S6 kinase polypeptide 1; ribosomal protein S6 kinase, 90kD, polypeptide 1; Ribosomal protein S6 kinase, 90kD, 1; ribosomal protein S6 kinase, 90kDa, polypeptide 1; ribosomal protein S6 kinase, 90kDa, polypeptide 1 L homeolog; ribosomal protein S6 kinas
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
20111, 6195, 81771
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid