PIMA542518
TrkB Recombinant Rabbit Monoclonal Antibody (JE58-22), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA542518-Each-of-1 | In Stock | ₹ 44,020.62 |
PIMA542518 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,020.62
GST (18%): ₹ 7,923.712
Total Price: ₹ 51,944.332
Antigen
TrkB
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P15209, Q16620, Q63604
Gene Symbols
Ntrk2
Immunogen
Recombinant protein within human TrkB aa 100-450
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Clone
JE58-22
Conjugate
Unconjugated
Gene
Ntrk2
Gene Alias
AI848316; BDNF/NT-3 growth factors receptor; BDNF-tropomyosine receptor kinase B; C030027L06Rik; EC 2.7.10.1; GP145 TrkB; GP145TrkB; GP145-TrkB; GP145-TrkB/GP95-TrkB; GP95 TrkB; GP95-TrkB; hyperphagia; kinase TrkB; neural receptor protein-tyrosine kinase (trkB); neurotrophic receptor tyrosine kinase 2; neurotrophic tyrosine kinase receptor type 2; neurotrophic tyrosine kinase, receptor, type 2; neurotrophic tyrosine receptor kinase type 2; NTRK 2; Ntrk2; OTTHUMP00000021573; OTTHUMP00000021574; OTTHUMP00000021576; OTTHUMP00000021577; RATTRKB1; Tkrb; Trk B; TRKB; trk-B; trkB protein; trkB tyrosine kinase; TRKB1; Tropomyosin-related kinase B; tyrosine kinase receptor B
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
18212, 25054, 4915
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Positive Control: Mouse brain tissue lysate, mouse cerebellum tissue lysate, rat cerebellum tissue lysate
- Subcellular Location: Cell membrane, Endosome membrane, Early endosome membrane, axon, dendrite, perinuclear region, postsynaptic density
- NTRK2 (TRKB) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system
- NTRK2 is the receptor for brain-derived neurotrophic factor (BDNF)
- Together, NTRK2 and BDNF regulate both short-term synaptic functions and long-term potentiation of brain synapses
- TrkB is involved in the development and maintenance of the nervous system
- Moreover, Trk B is a tyrosine kinase gene highly related to Trk A
- Trk B expression is confined to tissues within the central and peripheral nervous systems
- The brain-derived neurotrophic factor (BDNF) and NT-3, but not NGF, can induce rapid phosphorylation on tyrosine of Trk B gp145, one of the receptors encoded by Trk B, although BDNF elicits a response at least two orders of magnitude greater than NT-3
- TrkB is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway
- Signaling through TrkB leads to cell differentiation
- Mutations in the TrkB gene have been associated with obesity and mood disorders
- Alternate transcriptional splice variants encoding different isoforms have been found for the TrkB gene.
Compare Similar Items
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Antigen: TrkB
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P15209, Q16620, Q63604
Gene Symbols: Ntrk2
Immunogen: Recombinant protein within human TrkB aa 100-450
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: JE58-22
Conjugate: Unconjugated
Gene: Ntrk2
Gene Alias: AI848316; BDNF/NT-3 growth factors receptor; BDNF-tropomyosine receptor kinase B; C030027L06Rik; EC 2.7.10.1; GP145 TrkB; GP145TrkB; GP145-TrkB; GP145-TrkB/GP95-TrkB; GP95 TrkB; GP95-TrkB; hyperphagia; kinase TrkB; neural receptor protein-tyrosine kinase (trkB); neurotrophic receptor tyrosine kinase 2; neurotrophic tyrosine kinase receptor type 2; neurotrophic tyrosine kinase, receptor, type 2; neurotrophic tyrosine receptor kinase type 2; NTRK 2; Ntrk2; OTTHUMP00000021573; OTTHUMP00000021574; OTTHUMP00000021576; OTTHUMP00000021577; RATTRKB1; Tkrb; Trk B; TRKB; trk-B; trkB protein; trkB tyrosine kinase; TRKB1; Tropomyosin-related kinase B; tyrosine kinase receptor B
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 18212, 25054, 4915
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
TrkB
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P15209, Q16620, Q63604
Gene Symbols:
Ntrk2
Immunogen:
Recombinant protein within human TrkB aa 100-450
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
JE58-22
Conjugate:
Unconjugated
Gene:
Ntrk2
Gene Alias:
AI848316; BDNF/NT-3 growth factors receptor; BDNF-tropomyosine receptor kinase B; C030027L06Rik; EC 2.7.10.1; GP145 TrkB; GP145TrkB; GP145-TrkB; GP145-TrkB/GP95-TrkB; GP95 TrkB; GP95-TrkB; hyperphagia; kinase TrkB; neural receptor protein-tyrosine kinase (trkB); neurotrophic receptor tyrosine kinase 2; neurotrophic tyrosine kinase receptor type 2; neurotrophic tyrosine kinase, receptor, type 2; neurotrophic tyrosine receptor kinase type 2; NTRK 2; Ntrk2; OTTHUMP00000021573; OTTHUMP00000021574; OTTHUMP00000021576; OTTHUMP00000021577; RATTRKB1; Tkrb; Trk B; TRKB; trk-B; trkB protein; trkB tyrosine kinase; TRKB1; Tropomyosin-related kinase B; tyrosine kinase receptor B
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
18212, 25054, 4915
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: MBD2
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q9UBB5, Q9Z2E1
Gene Symbols: Mbd2
Immunogen: Recombinant protein within human MBD2 aa 50-200
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone: JE57-73
Conjugate: Unconjugated
Gene: Mbd2
Gene Alias: demethylase; DKFZp586O0821; DMTase; MBD2; MBD2a; methyl-CpG binding domain protein 2; methyl-CpG-binding domain protein 2; Methyl-CpG-binding protein MBD2; NY-CO-41
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 17191, 680172, 8932
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
MBD2
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q9UBB5, Q9Z2E1
Gene Symbols:
Mbd2
Immunogen:
Recombinant protein within human MBD2 aa 50-200
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone:
JE57-73
Conjugate:
Unconjugated
Gene:
Mbd2
Gene Alias:
demethylase; DKFZp586O0821; DMTase; MBD2; MBD2a; methyl-CpG binding domain protein 2; methyl-CpG-binding domain protein 2; Methyl-CpG-binding protein MBD2; NY-CO-41
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
17191, 680172, 8932
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: EGR1
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P18146
Gene Symbols: EGR1
Immunogen: Recombinant protein within human EGR1 aa 1-200
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: JE57-62
Conjugate: Unconjugated
Gene: EGR1
Gene Alias: A530045N19Rik; AT225; early growth response 1; early growth response protein 1; egr; EGR1; EGR-1; ETR103; G0S30; Krox-1; Krox24; Krox-24; Krox-24 nuclear protein; Nerve growth factor-induced protein A; Ngf1; NGF1-A; Ngfi; NGFIA; NGFI-A; TIS8; transcription factor ETR103; Transcription factor Zif268; Zenk; Zfp-6; Zif268; zif-268; Zinc finger protein 225; zinc finger protein Krox-24; ZNF225
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1958
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
EGR1
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P18146
Gene Symbols:
EGR1
Immunogen:
Recombinant protein within human EGR1 aa 1-200
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
JE57-62
Conjugate:
Unconjugated
Gene:
EGR1
Gene Alias:
A530045N19Rik; AT225; early growth response 1; early growth response protein 1; egr; EGR1; EGR-1; ETR103; G0S30; Krox-1; Krox24; Krox-24; Krox-24 nuclear protein; Nerve growth factor-induced protein A; Ngf1; NGF1-A; Ngfi; NGFIA; NGFI-A; TIS8; transcription factor ETR103; Transcription factor Zif268; Zenk; Zfp-6; Zif268; zif-268; Zinc finger protein 225; zinc finger protein Krox-24; ZNF225
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1958
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: HDGF
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P51858, P51859, Q8VHK7
Gene Symbols: HDGF
Immunogen: Recombinant protein within human HDGF aa 50-200
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: JE56-32
Conjugate: Unconjugated
Gene: HDGF
Gene Alias: AI118077; D3Ertd299e; DKFZp686J1764; FLJ96580; Hdgf; Hepatoma-derived growth factor; high mobility group protein 1-like 2; HMG1L2; HMG-1L2; Tdrm1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 114499, 15191, 3068
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
HDGF
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P51858, P51859, Q8VHK7
Gene Symbols:
HDGF
Immunogen:
Recombinant protein within human HDGF aa 50-200
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
JE56-32
Conjugate:
Unconjugated
Gene:
HDGF
Gene Alias:
AI118077; D3Ertd299e; DKFZp686J1764; FLJ96580; Hdgf; Hepatoma-derived growth factor; high mobility group protein 1-like 2; HMG1L2; HMG-1L2; Tdrm1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
114499, 15191, 3068
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid