PIMA542684
SMAD2 Recombinant Rabbit Monoclonal Antibody (2E3D8), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA542684-Each-of-1 | In Stock | ₹ 44,020.62 |
PIMA542684 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,020.62
GST (18%): ₹ 7,923.712
Total Price: ₹ 51,944.332
Antigen
SMAD2
Classification
Recombinant Monoclonal
Concentration
0.95 mg/mL
Formulation
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
O70436, Q15796, Q62432
Gene Symbols
SMAD2
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Smad2 (Q15796).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
2E3D8
Conjugate
Unconjugated
Gene
SMAD2
Gene Alias
7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17126, 29357, 4087
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Positive test controls include: HeLa, HT-29, Jurkat, NIH/3T3, Rat lung
- The target is usually found in the following locations: Cytoplasm, Nucleus
- Immunogen sequence: MSSILPFTPP VVKRLLGWKK SAGGSGGAGG GEQNGQEEKW CEKAVKSLVK KLKKTGRLDE LEKAITTQNC NTKCVTIPST CSEIWGLSTP NTIDQWDTTG SMAD2 (MADH2, MAD2) regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation
- SMAD2 interacts with the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation into the nucleus is a central event in TGF beta signaling
- Phosphorylation of threonine 8 in the calmodulin-binding region of the MH1 domain by extracellular signal regulated kinase 1 (ERK1) enhances SMAD2 transcriptional activity, which is negatively regulated by calmodulin
- In response to the TGF-beta signal, SMAD2 is phosphorylated by the TGF-beta receptors
- The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4
- The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors
- SMAD2 can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin
- Alternatively spliced transcript variants encoding the SMAD2 protein have been observed.
Compare Similar Items
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Antigen: SMAD2
Classification: Recombinant Monoclonal
Concentration: 0.95 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: O70436, Q15796, Q62432
Gene Symbols: SMAD2
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Smad2 (Q15796).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 2E3D8
Conjugate: Unconjugated
Gene: SMAD2
Gene Alias: 7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17126, 29357, 4087
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
SMAD2
Classification:
Recombinant Monoclonal
Concentration:
0.95 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
O70436, Q15796, Q62432
Gene Symbols:
SMAD2
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Smad2 (Q15796).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
2E3D8
Conjugate:
Unconjugated
Gene:
SMAD2
Gene Alias:
7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17126, 29357, 4087
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: LPP
Classification: Recombinant Monoclonal
Concentration: 0.33 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q5XI07, Q8BFW7, Q93052
Gene Symbols: LPP
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LPP (Q93052).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 8M2R8
Conjugate: Unconjugated
Gene: LPP
Gene Alias: 9430020K16Rik; AA959454; AU024130; B130055L10Rik; C79715; D630048H16; I79_000864; LIM domain containing preferred translocation partner in lipoma; LIM domain-containing preferred translocation partner in lipoma; LIM protein; lipoma preferred partner; Lipoma-preferred partner; Lipoma-preferred partner homolog; Lipoma-preferred-partner; LPP
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 210126, 288010, 4026
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
LPP
Classification:
Recombinant Monoclonal
Concentration:
0.33 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q5XI07, Q8BFW7, Q93052
Gene Symbols:
LPP
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LPP (Q93052).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
8M2R8
Conjugate:
Unconjugated
Gene:
LPP
Gene Alias:
9430020K16Rik; AA959454; AU024130; B130055L10Rik; C79715; D630048H16; I79_000864; LIM domain containing preferred translocation partner in lipoma; LIM domain-containing preferred translocation partner in lipoma; LIM protein; lipoma preferred partner; Lipoma-preferred partner; Lipoma-preferred partner homolog; Lipoma-preferred-partner; LPP
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
210126, 288010, 4026
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: MYH7B
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: A2AQP0
Gene Symbols: MYH7B
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1750-1983 of human MYH7B (NP_0659353)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: 7W8J3
Conjugate: Unconjugated
Gene: MYH7B
Gene Alias: __
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 311570, 668940
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
MYH7B
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
A2AQP0
Gene Symbols:
MYH7B
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1750-1983 of human MYH7B (NP_0659353)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
7W8J3
Conjugate:
Unconjugated
Gene:
MYH7B
Gene Alias:
__
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
311570, 668940
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: GUSB
Classification: Recombinant Monoclonal
Concentration: 1.5 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P08236
Gene Symbols: GUSB
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human beta glucuronidase (GUSB) (NP_0001722)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: 4U0E2
Conjugate: Unconjugated
Gene: GUSB
Gene Alias: Ac2-223; adipose storage deficiency; AI747421; asd; beta glucuronidase; beta-D-glucuronidase; beta-G1; Beta-glucuronidase; BG; g; glucuronidase beta; glucuronidase, beta; Gur; Gus; Gusb; Gus-r; Gus-s; Gus-t; Gus-u; Gut; lysosomal enzyme; MPS7; si:ch211-160e1.7; si:ct573103.7
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2990
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
GUSB
Classification:
Recombinant Monoclonal
Concentration:
1.5 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P08236
Gene Symbols:
GUSB
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human beta glucuronidase (GUSB) (NP_0001722)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
4U0E2
Conjugate:
Unconjugated
Gene:
GUSB
Gene Alias:
Ac2-223; adipose storage deficiency; AI747421; asd; beta glucuronidase; beta-D-glucuronidase; beta-G1; Beta-glucuronidase; BG; g; glucuronidase beta; glucuronidase, beta; Gur; Gus; Gusb; Gus-r; Gus-s; Gus-t; Gus-u; Gut; lysosomal enzyme; MPS7; si:ch211-160e1.7; si:ct573103.7
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2990
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid