PIMA542908

NEDD4L Recombinant Rabbit Monoclonal Antibody (3W9J2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA542908-Each-of-1 In Stock ₹ 44,020.62

PIMA542908 - Each of 1

₹ 44,020.62

In Stock

Quantity

1

Base Price: ₹ 44,020.62

GST (18%): ₹ 7,923.712

Total Price: ₹ 51,944.332

Antigen

NEDD4L

Classification

Recombinant Monoclonal

Concentration

0.75 mg/mL

Formulation

PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q96PU5

Gene Symbols

NEDD4L

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 876-975 of human NEDD4L (Q96PU5).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Clone

3W9J2

Conjugate

Unconjugated

Gene

NEDD4L

Gene Alias

1300012C07Rik; E3 ubiquitin-protein ligase NEDD4-like; FLJ33870; HECT-type E3 ubiquitin transferase NED4L; hNEDD4-2; KIAA0439; NEDD4; NEDD4 like E3 ubiquitin protein ligase; NEDD4.2; Nedd4-2; nedd4b; NEDD4L; NEDL3; neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase; neural precursor cell expressed, developmentally down-regulated gene 4b; neural precursor cell expressed, developmentally down-regulated gene 4-like; RSP5; ubiquitin-protein ligase Nedd4-2; ubiquitin-protein ligase Rsp5; Unknown (protein for IMAGE:7986262)

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23327

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Positive test controls include: HeLa, K-562
  • Immunogen sequence: NHPVIQWFWK AVLLMDAEKR IRLLQFVTGT SRVPMNGFAE LYGSNGPQLF TIEQWGSPEK LPRAHTCFNR LDLPPYETFE DLREKLLMAV ENAQGFEGVD NEDD4L is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates
  • NEDD4L inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation
  • NEDD4L promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5
  • NEDD4L also promotes ubiquitination and degradation of SGK.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA542908

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Antigen:
NEDD4L

Classification:
Recombinant Monoclonal

Concentration:
0.75 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q96PU5

Gene Symbols:
NEDD4L

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 876-975 of human NEDD4L (Q96PU5).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
3W9J2

Conjugate:
Unconjugated

Gene:
NEDD4L

Gene Alias:
1300012C07Rik; E3 ubiquitin-protein ligase NEDD4-like; FLJ33870; HECT-type E3 ubiquitin transferase NED4L; hNEDD4-2; KIAA0439; NEDD4; NEDD4 like E3 ubiquitin protein ligase; NEDD4.2; Nedd4-2; nedd4b; NEDD4L; NEDL3; neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase; neural precursor cell expressed, developmentally down-regulated gene 4b; neural precursor cell expressed, developmentally down-regulated gene 4-like; RSP5; ubiquitin-protein ligase Nedd4-2; ubiquitin-protein ligase Rsp5; Unknown (protein for IMAGE:7986262)

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23327

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA542909

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Antigen:
KIF4A

Classification:
Recombinant Monoclonal

Concentration:
1.65 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O95239, P33174

Gene Symbols:
Kif4, Kif4a

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human KIF4A (O95239).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
4A9P2

Conjugate:
Unconjugated

Gene:
Kif4a

Gene Alias:
AI323435; Chromokinesin; chromokinesin-A; Chromosome-associated kinesin KIF4; chromosome-associated kinesin KIF4A; D330050K22Rik; FLJ12530; FLJ12655; FLJ14204; FLJ20631; HSA271784; KIF4; KIF4A; KIF4G1; KIF4-G1; kinesin family member 4; kinesin family member 4A; kinesin heavy chain member 4; Kns4; MRX100; N-5 kinesin

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16571, 24137, 84393

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA542910

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Antigen:
NFIB

Classification:
Recombinant Monoclonal

Concentration:
1.24 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O00712, P97863

Gene Symbols:
NFIB

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 321-420 of human NFIB / NF1B2 (NP_0055872)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
7T1G5

Conjugate:
Unconjugated

Gene:
NFIB

Gene Alias:
6720429L07Rik; CCAAT-box-binding transcription factor; CTF; E030026I10Rik; HMGIC/NFIB; NF1-B; NF-I/B; Nfib; NFI-B; NFIB2; NFIB3; NFI-RED; nuclear factor 1 B-type; nuclear factor 1/B; nuclear factor I B; nuclear factor I/B; olfactory epithelium nuclear factor I-B; TGGCA-binding protein

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18028, 4781

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA542911

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Antigen:
Ephrin A1

Classification:
Recombinant Monoclonal

Concentration:
0.45 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P20827, P52793

Gene Symbols:
EFNA1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Ephrin A1 (P20827).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
5D4Q5

Conjugate:
Unconjugated

Gene:
EFNA1

Gene Alias:
AI325262; B61; ECKLG; EFL1; Efna1; Epgl1; EPH-related receptor tyrosine kinase ligand 1; ephrin A1; ephrin-A1; Ephrin-A1, secreted form; Epl1; EPLG1; Immediate early response protein B61; Lerk1; LERK-1; ligand of eph-related kinase 1; TNF alpha-induced protein 4; TNFAIP4; tumor necrosis factor alpha-induced protein 4; tumor necrosis factor, alpha-induced protein 4

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13636, 1942

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid