PIMA543078

PD-1 Recombinant Human Monoclonal Antibody (HN94), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA543078-Each-of-1 In Stock ₹ 44,020.62

PIMA543078 - Each of 1

₹ 44,020.62

In Stock

Quantity

1

Base Price: ₹ 44,020.62

GST (18%): ₹ 7,923.712

Total Price: ₹ 51,944.332

Antigen

PD-1

Classification

Recombinant Monoclonal

Concentration

5.08 mg/mL

Formulation

arginine, histidine with 0.02% Tween 80, 120mM NaCl and no preservative

Gene Accession No.

Q15116

Gene Symbols

Pdcd1

Immunogen

Recombinant Human PD1/PDCD1/CD279 Protein.

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG4

Applications

Neutralization

Clone

HN94

Conjugate

Unconjugated

Gene

Pdcd1

Gene Alias

CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2

Host Species

Human

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

5133

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Specificity: Human PD1/PDCD1/CD279 KD of the antibody is <1.43E-10 M for PD1 (10377-H08H)
  • Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC)
  • T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC
  • PD-1 can bind two different but related ligands, PDL-1 and PDL-2
  • Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of &quotedanger signals&quote such as LPS or other molecules associated with bacteria or other pathogens
  • Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases
  • Despite its predicted molecular weight, PD-1 often migrates at higher molecular weight in SDS-PAGE.

Compare Similar Items

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Img

Thermo Scientific

PIMA543078

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Antigen:
PD-1

Classification:
Recombinant Monoclonal

Concentration:
5.08 mg/mL

Formulation:
arginine, histidine with 0.02% Tween 80, 120mM NaCl and no preservative

Gene Accession No.:
Q15116

Gene Symbols:
Pdcd1

Immunogen:
Recombinant Human PD1/PDCD1/CD279 Protein.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG4

Applications:
Neutralization

Clone:
HN94

Conjugate:
Unconjugated

Gene:
Pdcd1

Gene Alias:
CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2

Host Species:
Human

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5133

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

PIMA543082

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Antigen:
CLEC4A

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q9UMR7

Gene Symbols:
CLEC4A

Immunogen:
Recombinant Human DCIR/CLEC4A/CLECSF6 protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA

Clone:
007

Conjugate:
Unconjugated

Gene:
CLEC4A

Gene Alias:
CD367; CLEC4A; Clec4a2; Clecsf6; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 6; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6; C-type lectin DDB27; C-type lectin domain family 4 member A; C-type lectin domain family 4, member A; C-type lectin domain family 4, member a2; C-type lectin superfamily member 6; DCIR; Dcir1; Dcir2; DDB27; Dendritic cell immunoreceptor; dendritic cell inhibitory receptor 1; dendritic cell inhibitory receptor 2; HDCGC13P; immunoreceptor; lectin-like immunoreceptor; LLIR

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
50856

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA543084

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Antigen:
DKK1

Classification:
Recombinant Monoclonal

Concentration:
1.96 mg/mL

Formulation:
arginine, histidine with 0.02% Tween 80, 120mM NaCl and no preservative

Gene Accession No.:
O94907

Gene Symbols:
DKK1

Immunogen:
Recombinant Human DKK-1 Protein.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Neutralization

Clone:
R015

Conjugate:
Unconjugated

Gene:
DKK1

Gene Alias:
dickkopf 1 homolog; dickkopf homolog 1; dickkopf homolog 1 (Xenopus laevis); dickkopf related protein-1; dickkopf WNT signaling pathway inhibitor 1; Dickkopf1; dickkopf-1; dickkopf-1 like; dickkopf-like protein 1; dickkopf-related protein 1; DKK1; DKK-1; hDkk1; hDkk-1; mdkk-1; SK; UNQ492/PRO1008

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
22943

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

PIMA543086

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Antigen:
Ephrin A1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P97553

Gene Symbols:
EFNA1

Immunogen:
Recombinant Rat Ephrin-A1/EFNA1 Protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA

Clone:
067

Conjugate:
Unconjugated

Gene:
EFNA1

Gene Alias:
AI325262; B61; ECKLG; EFL1; Efna1; Epgl1; EPH-related receptor tyrosine kinase ligand 1; ephrin A1; ephrin-A1; Ephrin-A1, secreted form; Epl1; EPLG1; Immediate early response protein B61; Lerk1; LERK-1; ligand of eph-related kinase 1; TNF alpha-induced protein 4; TNFAIP4; tumor necrosis factor alpha-induced protein 4; tumor necrosis factor, alpha-induced protein 4

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
94268

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid