PIMA543403

ST2 Monoclonal Antibody (12), Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA543403-Each-of-1 In Stock ₹ 22,801.74

PIMA543403 - Each of 1

₹ 22,801.74

In Stock

Quantity

1

Base Price: ₹ 22,801.74

GST (18%): ₹ 4,104.313

Total Price: ₹ 26,906.053

Antigen

ST2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

Q01638

Gene Symbols

IL1RL1

Immunogen

Recombinant human IL1RL1/IL1R4 protein

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

Applications

ELISA

Clone

12

Conjugate

Unconjugated

Gene

IL1RL1

Gene Alias

DER4; Fit1; Fit-1; Fos-responsive gene 1 protein; growth stimulation-expressed; homolog of mouse growth stimulation-expressed; IL-1 R4; IL1RL1; IL-1RL1; IL33R; IL-33R; interleukin 1 receptor like 1; interleukin 1 receptor-like 1; interleukin 1 receptor-related protein; Interleukin1 receptor like 1; interleukin-1 receptor-like 1; Interleukin-33 receptor alpha chain; Ly84; lymphocyte antigen 84; Protein ST2; Protein T1; sIL 33R; soluble IL 33 Receptor; soluble IL 33R; St2; ST2L; St2-rs1; ST2V; Ste2; T1; T1/ST2

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

9173

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Description

  • Specificity: Human IL1RL1/IL1R4 IL-33R, also known as ST2, is a receptor for IL-33
  • It is a member of the IL-1 receptor family of innate receptors
  • Its extracellular domain consists of 3 Ig-like domains that directly interact with its co-receptor IL-1RAcP, and the ligand alarmin, IL-33
  • IL-33 ligation results in the association of IL-33R complex with its adaptor proteins MyD88, IRAK1, IRAK4 and TRAF6, and activation of the NF-kB, and MAPK pathways
  • This, in turn, instigates the release of chemokines and cytokines such as IL-5, IL-6, IL-8, and IL-13
  • Two most common isoforms of IL-33R that result from alternative splicing are ST2L – the membrane bound form, and ST2S – the soluble form
  • The membrane bound form can be released from the cell surface by proteolytic cleavage
  • The soluble forms have been suggested to act as decoys dampening the IL-33 signaling
  • IL-33R is primarily expressed by mast cells, basophils, and eosinophils
  • In mouse, IL-33R expression has been shown on ILC2 and Th2 cells
  • IL-33R signaling has been implicated in the number of immune conditions, including allergies, arthritis, atherosclerosis and sepsis.

Compare Similar Items

Show Difference

Img

Fischer Scientific

PIMA543403

--


Antigen:
ST2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q01638

Gene Symbols:
IL1RL1

Immunogen:
Recombinant human IL1RL1/IL1R4 protein

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
ELISA

Clone:
12

Conjugate:
Unconjugated

Gene:
IL1RL1

Gene Alias:
DER4; Fit1; Fit-1; Fos-responsive gene 1 protein; growth stimulation-expressed; homolog of mouse growth stimulation-expressed; IL-1 R4; IL1RL1; IL-1RL1; IL33R; IL-33R; interleukin 1 receptor like 1; interleukin 1 receptor-like 1; interleukin 1 receptor-related protein; Interleukin1 receptor like 1; interleukin-1 receptor-like 1; Interleukin-33 receptor alpha chain; Ly84; lymphocyte antigen 84; Protein ST2; Protein T1; sIL 33R; soluble IL 33 Receptor; soluble IL 33R; St2; ST2L; St2-rs1; ST2V; Ste2; T1; T1/ST2

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9173

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

PIMA543404

--


Antigen:
ST2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 10% trehalose and no preservative

Gene Accession No.:
Q01638

Gene Symbols:
IL1RL1

Immunogen:
Recombinant Human IL1RL1/IL1R4 Protein

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA

Clone:
10

Conjugate:
Unconjugated

Gene:
IL1RL1

Gene Alias:
DER4; Fit1; Fit-1; Fos-responsive gene 1 protein; growth stimulation-expressed; homolog of mouse growth stimulation-expressed; IL-1 R4; IL1RL1; IL-1RL1; IL33R; IL-33R; interleukin 1 receptor like 1; interleukin 1 receptor-like 1; interleukin 1 receptor-related protein; Interleukin1 receptor like 1; interleukin-1 receptor-like 1; Interleukin-33 receptor alpha chain; Ly84; lymphocyte antigen 84; Protein ST2; Protein T1; sIL 33R; soluble IL 33 Receptor; soluble IL 33R; St2; ST2L; St2-rs1; ST2V; Ste2; T1; T1/ST2

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9173

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

PIMA543405

--


Antigen:
TrkC

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q16288

Gene Symbols:
Ntrk3

Immunogen:
Recombinant Human TrkC/NTRK3 Protein.

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA

Clone:
11

Conjugate:
Unconjugated

Gene:
Ntrk3

Gene Alias:
AW125844; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp145(trkC); GP145-TrkC; neural receptor protein-tyrosine kinase (trkC); neurotrophic receptor tyrosine kinase 3; Neurotrophic tyrosine kinase receptor type 3; neurotrophic tyrosine kinase, receptor, type 3; neurotrophin-3; NT-3 growth factor receptor; NTRK3; Ntrk3_tv3; TrkC; trk-C; trkC tyrosine kinase; tyrosine kinase receptor; tyrosine kinase receptor C

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4916

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

PIMA543406

--


Antigen:
TrkC

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q16288

Gene Symbols:
Ntrk3

Immunogen:
Recombinant Human TrkC/NTRK3 Protein.

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA

Clone:
08

Conjugate:
Unconjugated

Gene:
Ntrk3

Gene Alias:
AW125844; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp145(trkC); GP145-TrkC; neural receptor protein-tyrosine kinase (trkC); neurotrophic receptor tyrosine kinase 3; Neurotrophic tyrosine kinase receptor type 3; neurotrophic tyrosine kinase, receptor, type 3; neurotrophin-3; NT-3 growth factor receptor; NTRK3; Ntrk3_tv3; TrkC; trk-C; trkC tyrosine kinase; tyrosine kinase receptor; tyrosine kinase receptor C

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4916

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid