PIMA543718
Nephrin Monoclonal Antibody (C8), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA543718-Each-of-1 | In Stock | ₹ 17,017.88 |
PIMA543718 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,017.88
GST (18%): ₹ 3,063.218
Total Price: ₹ 20,081.098
Antigen
Nephrin
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.
O60500
Gene Symbols
Nphs1
Immunogen
Recombinant protein Nephrin. The antigen corresponds to amino acid range 27-234 of the target protein.
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a κ
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
C8
Conjugate
Unconjugated
Gene
Nphs1
Gene Alias
CNF; Nephrin; nephrin 1; NephrinB; nephrosis 1 homolog, nephrin; nephrosis 1, congenital, Finnish type (nephrin); nephrosis 1, nephrin; NPHN; NPHS1; NPHS1 nephrin; NPHS1, nephrin; renal glomerulus-specific cell adhesion receptor
Host Species
Mouse
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
4868
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Primary steroid resistant nephrotic syndrome (SRNS) is characterized by childhood onset of proteinuria and progression to end stage renal disease
- Kidney podocytes and their slit diaphragms form the final barrier to urinary protein loss
- Congenital nephrotic syndrome (CNS) is caused by mutations in NPHS1 (nephrin) or NPHS2
- Nephrin, a recently identified protein is a member of a group of podocyte proteins that constitute major component of the slit diaphragm especially in the foot process
- Nephrin, a cell adhesion molecule, may play a crucial role in maintaining the glomerular filtration barrier
- Recent studies have suggested that mutations in the gene for Nephrin reportedly lead to congenital nephrosis
- Three novel podocyte proteins, Podocin, Nephrin and alpha Actinin 4 have been identified in congenital and experimental models of proteinuria
- The role of Nephrin in anti apoptotic activity in podocyte slit diaphragm is believed to be associated with vascular endothelial derived growth factors VEGF signaling
- Nephrin seems to play a role in the development or function of the kidney glomerular filtration barrier and it may anchor the podocyte slit diaphragm to the actin cytoskeleton.
Compare Similar Items
Show Difference
Antigen: Nephrin
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.: O60500
Gene Symbols: Nphs1
Immunogen: Recombinant protein Nephrin. The antigen corresponds to amino acid range 27-234 of the target protein.
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a κ
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: C8
Conjugate: Unconjugated
Gene: Nphs1
Gene Alias: CNF; Nephrin; nephrin 1; NephrinB; nephrosis 1 homolog, nephrin; nephrosis 1, congenital, Finnish type (nephrin); nephrosis 1, nephrin; NPHN; NPHS1; NPHS1 nephrin; NPHS1, nephrin; renal glomerulus-specific cell adhesion receptor
Host Species: Mouse
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 4868
Content And Storage: -20°C
Form: Liquid
Antigen:
Nephrin
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.:
O60500
Gene Symbols:
Nphs1
Immunogen:
Recombinant protein Nephrin. The antigen corresponds to amino acid range 27-234 of the target protein.
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a κ
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
C8
Conjugate:
Unconjugated
Gene:
Nphs1
Gene Alias:
CNF; Nephrin; nephrin 1; NephrinB; nephrosis 1 homolog, nephrin; nephrosis 1, congenital, Finnish type (nephrin); nephrosis 1, nephrin; NPHN; NPHS1; NPHS1 nephrin; NPHS1, nephrin; renal glomerulus-specific cell adhesion receptor
Host Species:
Mouse
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
4868
Content And Storage:
-20°C
Form:
Liquid
Antigen: KPNA2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.: P52292
Gene Symbols: KPNA2
Immunogen: Recombinant protein Karyopherin Alpha 2. The antigen corresponds to amino acid range 157-412 of the target protein.
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a κ
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: C8
Conjugate: Unconjugated
Gene: KPNA2
Gene Alias: 2410044B12Rik; IMA2; importin; importin alpha 2; importin alpha P1; Importin subunit alpha-1; importin subunit alpha-2; importin-alpha-P1; IPOA 1; IPOA1; IPOA1 QIP2; karyopherin (importin) alpha 2; Karyopherin A2; karyopherin alpha 2; karyopherin alpha 2 (RAG cohort 1, importin alpha 1); karyopherin subunit alpha 2; karyopherin subunit alpha-2; Kpna2; m-importin-alpha-P1; nuclear import protein; pendulin; Pore targeting complex 58 kDa subunit; PTAC58; QIP2; RAG cohort 1; RAG cohort protein 1; RCH 1; RCH1; SRP 1; SRP1; SRP1 alpha; SRP1alpha; SRP1-alpha
Host Species: Mouse
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 3838
Content And Storage: -20°C
Form: Liquid
Antigen:
KPNA2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.:
P52292
Gene Symbols:
KPNA2
Immunogen:
Recombinant protein Karyopherin Alpha 2. The antigen corresponds to amino acid range 157-412 of the target protein.
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a κ
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
C8
Conjugate:
Unconjugated
Gene:
KPNA2
Gene Alias:
2410044B12Rik; IMA2; importin; importin alpha 2; importin alpha P1; Importin subunit alpha-1; importin subunit alpha-2; importin-alpha-P1; IPOA 1; IPOA1; IPOA1 QIP2; karyopherin (importin) alpha 2; Karyopherin A2; karyopherin alpha 2; karyopherin alpha 2 (RAG cohort 1, importin alpha 1); karyopherin subunit alpha 2; karyopherin subunit alpha-2; Kpna2; m-importin-alpha-P1; nuclear import protein; pendulin; Pore targeting complex 58 kDa subunit; PTAC58; QIP2; RAG cohort 1; RAG cohort protein 1; RCH 1; RCH1; SRP 1; SRP1; SRP1 alpha; SRP1alpha; SRP1-alpha
Host Species:
Mouse
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
3838
Content And Storage:
-20°C
Form:
Liquid
Antigen: Klotho
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.: Q9UEF7, Q9Z2Y9
Gene Symbols: KL
Immunogen: Phe765-Ser981 (Accession Q9UEF7), with Two N-terminal Tags, His-tag and SUMO-tag
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG1 κ
Applications: Western Blot
Clone: C3
Conjugate: Unconjugated
Gene: KL
Gene Alias: alpha-kl; HFTC3; Kl; Klotho; Klotho peptide; secreted form of Klotho protein
Host Species: Mouse
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 83504, 9365
Content And Storage: -20°C
Form: Liquid
Antigen:
Klotho
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.:
Q9UEF7, Q9Z2Y9
Gene Symbols:
KL
Immunogen:
Phe765-Ser981 (Accession Q9UEF7), with Two N-terminal Tags, His-tag and SUMO-tag
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
C3
Conjugate:
Unconjugated
Gene:
KL
Gene Alias:
alpha-kl; HFTC3; Kl; Klotho; Klotho peptide; secreted form of Klotho protein
Host Species:
Mouse
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
83504, 9365
Content And Storage:
-20°C
Form:
Liquid
Antigen: Klotho
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.: Q9UEF7, Q9Z2Y9
Gene Symbols: KL
Immunogen: Phe765-Ser981 (Accession Q9UEF7), with Two N-terminal Tags, His-tag and SUMO-tag
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG1 κ
Applications: Western Blot
Clone: C3
Conjugate: Unconjugated
Gene: KL
Gene Alias: alpha-kl; HFTC3; Kl; Klotho; Klotho peptide; secreted form of Klotho protein
Host Species: Mouse
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 83504, 9365
Content And Storage: -20°C
Form: Liquid
Antigen:
Klotho
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.:
Q9UEF7, Q9Z2Y9
Gene Symbols:
KL
Immunogen:
Phe765-Ser981 (Accession Q9UEF7), with Two N-terminal Tags, His-tag and SUMO-tag
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
C3
Conjugate:
Unconjugated
Gene:
KL
Gene Alias:
alpha-kl; HFTC3; Kl; Klotho; Klotho peptide; secreted form of Klotho protein
Host Species:
Mouse
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
83504, 9365
Content And Storage:
-20°C
Form:
Liquid