PIMA543747

IGF1 Monoclonal Antibody (C1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA543747-Each-of-1 In Stock ₹ 12,893.89

PIMA543747 - Each of 1

₹ 12,893.89

In Stock

Quantity

1

Base Price: ₹ 12,893.89

GST (18%): ₹ 2,320.90

Total Price: ₹ 15,214.79

Antigen

IGF1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

P05019

Gene Symbols

IGF1

Immunogen

Recombinant protein Insulin Like Growth Factor 1. The antigen corresponds to amino acid range 49-118 of the target protein.

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b κ

Applications

Immunocytochemistry, Western Blot

Clone

C1

Conjugate

Unconjugated

Gene

IGF1

Gene Alias

C730016P09Rik; class 1 insulin-like growth factor I preproprotein; class 2 insulin-like growth factor I preproprotein; H-IGF-1; IBP1; IGF; IGF1; Igf-1; IGF1A; IGFI; Igf-I; IGFIa; IGF-IA; IGF-IB; insulin growth factor-1; Insulin like growth factor; insulin like growth factor 1; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor I; insulin-like growth factor I (somatomedin C); insulin-like growth factor IB; mechano growth factor; MGF; M-IGF-1; OTTHUMP00000195084; prepro-IGF-I; prepro-insulin-like growth factor I; R-IGF-1; somatomedin; Somatomedin C; Somatomedin-C

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

3479

Content And Storage

-20°C

Form

Liquid

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Description

  • IGF1 (Insulin-like growth factor-1) is structurally and functionally related to insulin but has a much higher growth-promoting activity
  • A variety of cellular responses are induced by IGF1, including cell proliferation, differentiation, migration, and survival
  • Further, IGF1 is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types in muscle, bone, and cartilage tissue
  • IGF1 stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regards to enhancing glucose uptake
  • In circulation, IGFs are predominantly bound to binding proteins (IGFBPs) which prolong the half-life of the IGFs and play a role in delivering them to target tissues
  • IGF-I is known as one of the most potent activators of the AKT signaling pathway which is known to be a stimulator of proliferation and an inhibitor of programmed cell death
  • Moreover, mature human IGF-I is 100% homologous with bovine and porcine proteins
  • Low levels of IGF1 have been linked to Alzheimer's disease
  • IGF1 is processed from a precursor, bound by a specific receptor, and secreted
  • Defects in the IGF1 gene are a cause of insulin-like growth factor 1 deficiency and several transcript variants encoding different isoforms have been found.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA543747

--


Antigen:
IGF1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P05019

Gene Symbols:
IGF1

Immunogen:
Recombinant protein Insulin Like Growth Factor 1. The antigen corresponds to amino acid range 49-118 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Immunocytochemistry, Western Blot

Clone:
C1

Conjugate:
Unconjugated

Gene:
IGF1

Gene Alias:
C730016P09Rik; class 1 insulin-like growth factor I preproprotein; class 2 insulin-like growth factor I preproprotein; H-IGF-1; IBP1; IGF; IGF1; Igf-1; IGF1A; IGFI; Igf-I; IGFIa; IGF-IA; IGF-IB; insulin growth factor-1; Insulin like growth factor; insulin like growth factor 1; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor I; insulin-like growth factor I (somatomedin C); insulin-like growth factor IB; mechano growth factor; MGF; M-IGF-1; OTTHUMP00000195084; prepro-IGF-I; prepro-insulin-like growth factor I; R-IGF-1; somatomedin; Somatomedin C; Somatomedin-C

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
3479

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA543748

--


Antigen:
IGFBP4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P22692

Gene Symbols:
IGFBP4

Immunogen:
Recombinant protein Insulin Like Growth Factor Binding Protein 4. The antigen corresponds to amino acid range 22-258 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
A3

Conjugate:
Unconjugated

Gene:
IGFBP4

Gene Alias:
AI875747; Band 3A; BP-4; Deb2; differentially expressed in B16F10 2; HT29-IGFBP; IBP4; IBP-4; IGF-binding protein 4; IGFBP; Igfbp4; IGF-BP4; IGFBP-4; Insulin like growth factor binding protein; insulin like growth factor binding protein 4; insulin-like growth factor binding protein 4; insulin-like growth factor binding protein-4; insulin-like growth factor-binding protein 4; insulin-like growth factor-binding protein-4; LOW QUALITY PROTEIN: insulin-like growth factor-binding protein 4

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
3487

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA543749

--


Antigen:
IGFBP4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P22692

Gene Symbols:
IGFBP4

Immunogen:
Recombinant protein Insulin Like Growth Factor Binding Protein 4. The antigen corresponds to amino acid range 22-258 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C15

Conjugate:
Unconjugated

Gene:
IGFBP4

Gene Alias:
AI875747; Band 3A; BP-4; Deb2; differentially expressed in B16F10 2; HT29-IGFBP; IBP4; IBP-4; IGF-binding protein 4; IGFBP; Igfbp4; IGF-BP4; IGFBP-4; Insulin like growth factor binding protein; insulin like growth factor binding protein 4; insulin-like growth factor binding protein 4; insulin-like growth factor binding protein-4; insulin-like growth factor-binding protein 4; insulin-like growth factor-binding protein-4; LOW QUALITY PROTEIN: insulin-like growth factor-binding protein 4

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
3487

Content And Storage:
-20°C

Form:
Liquid

Img

Fischer Scientific

PIMA543750

--


Antigen:
IGFBP4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P21744, P22692

Gene Symbols:
IGFBP4

Immunogen:
Asp22-Glu258 (Accession P22692), with N-terminal His Tag

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
A4

Conjugate:
Unconjugated

Gene:
IGFBP4

Gene Alias:
AI875747; Band 3A; BP-4; Deb2; differentially expressed in B16F10 2; HT29-IGFBP; IBP4; IBP-4; IGF-binding protein 4; IGFBP; Igfbp4; IGF-BP4; IGFBP-4; Insulin like growth factor binding protein; insulin like growth factor binding protein 4; insulin-like growth factor binding protein 4; insulin-like growth factor binding protein-4; insulin-like growth factor-binding protein 4; insulin-like growth factor-binding protein-4; LOW QUALITY PROTEIN: insulin-like growth factor-binding protein 4

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
3487, 360622

Content And Storage:
-20°C

Form:
Liquid