PIMA543862

Cyclophilin A Monoclonal Antibody (C10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA543862-Each-of-1 In Stock ₹ 17,017.88

PIMA543862 - Each of 1

₹ 17,017.88

In Stock

Quantity

1

Base Price: ₹ 17,017.88

GST (18%): ₹ 3,063.218

Total Price: ₹ 20,081.098

Antigen

Cyclophilin A

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

P62937

Gene Symbols

Ppia

Immunogen

Recombinant protein Cyclophilin A. The antigen corresponds to amino acid range 2-165 of the target protein.

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a κ

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

C10

Conjugate

Unconjugated

Gene

Ppia

Gene Alias

2700098C05; Cphn; CYCA; cyclophilin; Cyclophilin A; Cyclosporin A-binding protein; CyP A; CyP-18; CYPA; CyP-A; CYPH; EC 5.2.1.8; epididymis secretory sperm binding protein Li 69p; HEL-S-69p; HGNC:9253; I79_011869; MGC117158; MGC12404; MGC23397; p1B15; p31; Peptidyl-prolyl cis-trans isomerase A; Peptidyl-prolyl cis-trans isomerase A, N-terminally processed; peptidylprolyl isomerase A; peptidylprolyl isomerase A (cyclophilin A); PPIA; PPIase; PPIase A; rotamase; rotamase A; SP18; T cell cyclophilin

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

5478

Content And Storage

-20°C

Form

Liquid

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Description

  • Immunophilins are a family of soluble cytosolic receptors capable of binding to one of two major immunosuppressant agents - cyclosporin A (CsA) or FK506
  • Proteins that bind FK506 are termed FK506 Binding Proteins (FKBPs) and those that bind cyclosporin A are called cyclophilins (CyP)
  • Both CyP:CsA and FKBP:FK506 complexes have been shown to inhibit calcineurin, a calcium and calmodulin dependent protein phosphatase which has been implicated as an important signaling enzyme in T-cell activation, providing a possible mechanism of immunosuppression by CsA and FK506
  • Immunophilins function as peptidyl prolyl cis-trans-isomerases (PPIase) whose activity is inhibited by their respective immunosuppressant compounds
  • As PPIase's, immunophilins accelerate folding of some proteins both in vivo and in vitro by catalyzing slow steps in the initial folding and rearrangement of proline containing proteins
  • Within the cyclophilin family, there are several different proteins which show a high degree of homology including CyPA, CyPB and CyPC
  • CyPA, also termed CyP-18, is the most abundant and ubiquitous cyclophilin found in all vertebrate tissues and is present in T-cells.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA543862

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Antigen:
Cyclophilin A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P62937

Gene Symbols:
Ppia

Immunogen:
Recombinant protein Cyclophilin A. The antigen corresponds to amino acid range 2-165 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C10

Conjugate:
Unconjugated

Gene:
Ppia

Gene Alias:
2700098C05; Cphn; CYCA; cyclophilin; Cyclophilin A; Cyclosporin A-binding protein; CyP A; CyP-18; CYPA; CyP-A; CYPH; EC 5.2.1.8; epididymis secretory sperm binding protein Li 69p; HEL-S-69p; HGNC:9253; I79_011869; MGC117158; MGC12404; MGC23397; p1B15; p31; Peptidyl-prolyl cis-trans isomerase A; Peptidyl-prolyl cis-trans isomerase A, N-terminally processed; peptidylprolyl isomerase A; peptidylprolyl isomerase A (cyclophilin A); PPIA; PPIase; PPIase A; rotamase; rotamase A; SP18; T cell cyclophilin

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
5478

Content And Storage:
-20°C

Form:
Liquid

Img

Fischer Scientific

PIMA543865

--


Antigen:
CXCL12

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P48061

Gene Symbols:
CXCL12

Immunogen:
Pro23-Lys89 (Accession P48061), with N-terminal His and GST Tag

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
C3

Conjugate:
Unconjugated

Gene:
CXCL12

Gene Alias:
12-O-tetradecanoylphorbol 13-acetate repressed protein 1; AI174028; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 12; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); CXC; CXC motif chemokine; C-X-C motif chemokine 12; C-X-C motif chemokine ligand 12; CXCL; Cxcl12; hIRH; hSDF-1; Intercrine reduced in hepatomas; IRH; PBSF; pre-B cell growth-stimulating factor; pre-B-cell growth-stimulating factor; Scyb12; Sdf1; SDF-1; SDF-1 gamma; SDF1A; SDF-1a; SDF-1-alpha(3-67); SDF1B; SDF-1b; SDF-1-beta(3-72); Stromal cell-derived factor 1; stromal cell-derived factor-1 alpha; stromal cell-derived factor-1 gamma; thymic lymphoma cell-stimulating factor; TLSF; Tlsfa; TLSF-a; Tlsfb; TLSF-b; Tpar1

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
6387

Content And Storage:
-20°C

Form:
Liquid

Img

Fischer Scientific

PIMA543866

--


Antigen:
CXCL12

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P48061

Gene Symbols:
CXCL12

Immunogen:
Pro23-Lys89 (Accession P48061), with N-terminal His and GST Tag

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
C3

Conjugate:
Unconjugated

Gene:
CXCL12

Gene Alias:
12-O-tetradecanoylphorbol 13-acetate repressed protein 1; AI174028; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 12; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); CXC; CXC motif chemokine; C-X-C motif chemokine 12; C-X-C motif chemokine ligand 12; CXCL; Cxcl12; hIRH; hSDF-1; Intercrine reduced in hepatomas; IRH; PBSF; pre-B cell growth-stimulating factor; pre-B-cell growth-stimulating factor; Scyb12; Sdf1; SDF-1; SDF-1 gamma; SDF1A; SDF-1a; SDF-1-alpha(3-67); SDF1B; SDF-1b; SDF-1-beta(3-72); Stromal cell-derived factor 1; stromal cell-derived factor-1 alpha; stromal cell-derived factor-1 gamma; thymic lymphoma cell-stimulating factor; TLSF; Tlsfa; TLSF-a; Tlsfb; TLSF-b; Tpar1

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
6387

Content And Storage:
-20°C

Form:
Liquid

Img

Fischer Scientific

PIMA543867

--


Antigen:
CXCL10 (IP-10)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P02778

Gene Symbols:
CXCL10

Immunogen:
Val22-Pro98 (Accession P02778), with N-terminal His Tag

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
C3

Conjugate:
Unconjugated

Gene:
CXCL10

Gene Alias:
10 kDa interferon gamma-induced protein; 10 kDa interferon-gamma induced protein precursor; C Cmotif chemokine; C X C motif chemokine; C7; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 10; chemokine C-X-C motif ligand 10; chemokine CXC-like protein; Crg2; CRG-2; CXC; CXC chemokine; CXC motif chemokine; C-X-C motif chemokine 10; C-X-C motif chemokine 10-like protein; C-X-C motif chemokine ligand 10; CXCL; CXCL10; CXCL10(1-73); gamma interferon inducible protein 10; gamma IP10; gamma-IP10; gIP-10; H-IP-10; IFI10; Inp10; interferon activated gene 10; interferon-gamma induced protein CRG-2; interferon-gamma-induced protein CRG-2; interferon-gamma-inducible protein 10; interferon-gamma-inducible protein-10; interferon-inducible cytokine IP-10; interferon-inducible protein 10; IP10; IP-10; M-IP-10; Mob1; mob-1; protein 10 from interferon (gamma)-induced cell line; protein Mob-1; Scyb10; similar to Small inducible cytokine B10 precursor (CXCL10) (10 kDa interferon-gamm

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
3627

Content And Storage:
-20°C

Form:
Liquid