PIMA543920
Caspase 9 Monoclonal Antibody (C7), Invitrogen™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA543920-Each-of-1 | In Stock | ₹ 41,710.50 |
PIMA543920 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,710.50
GST (18%): ₹ 7,507.89
Total Price: ₹ 49,218.39
Antigen
Caspase 9
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.
P55211, Q8C3Q9
Gene Symbols
CASP9
Immunogen
Ala331-Leu411 (Accession P55211), with N-terminal His Tag
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2b κ
Applications
Immunohistochemistry (Paraffin)
Clone
C7
Conjugate
Unconjugated
Gene
CASP9
Gene Alias
25 kDa caspase-9 dominant negative protein; AI115399; APAF3; APAF-3; apoptotic protease activating factor 3; apoptotic protease MCH-6; Apoptotic protease-activating factor 3; AW493809; cas9; CASP 9; CASP9; CASP-9; Casp9_v1; Casp-9-CTD; caspase 9; caspase 9, apoptosis-related cysteine peptidase; caspase 9, apoptosis-related cysteine protease; Caspase9; caspase-9; caspase-9 dominant negative form; Caspase-9 precursor; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; caspase-9-carboxyl-terminal divergent; CTD; Ice-Lap6; ICE-like apoptotic protease 6; Mch6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9; RP11-265F14.3
Host Species
Mouse
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
12371, 842
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Caspase 9 (ICE-like apoptotic protease 6, ICE LAP6, apoptotic protease Mch6, apoptotic protease activating factor 3, Apaf3) is a member of the peptidase family C14 that contains a CARD domain
- Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates
- Caspase 9 is active as a heterotetramer, is present in the cytosol and, upon activation, translocates to the mitochondria
- Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6
- Further, Caspase 9 is involved in the activation cascade of caspases responsible for apoptosis execution
- Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3
- Caspase 9 promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner, and proteolytically cleaves poly(ADP- ribose) polymerase (PARP)
- Caspase 9 is expressed in variety of human tissues
- An isoform of rat Caspase-9 has been identified in which the C terminus of full-length Caspase-9 is replaced with an alternative peptide sequence
- Mutations in Caspase 9 affect brain development
- In mice, insufficient Caspase 9 have resulted in abnormal cerebrum development and neuron development
- In humans, dysfunctional Caspase 9 expression vary from tissue to tissue
- Low levels of Caspase 9 may play a role in cancer development and neurodegenerative diseases such as Alzheimer’s Disease (AD).
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Antigen: Caspase 9
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.: P55211, Q8C3Q9
Gene Symbols: CASP9
Immunogen: Ala331-Leu411 (Accession P55211), with N-terminal His Tag
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2b κ
Applications: Immunohistochemistry (Paraffin)
Clone: C7
Conjugate: Unconjugated
Gene: CASP9
Gene Alias: 25 kDa caspase-9 dominant negative protein; AI115399; APAF3; APAF-3; apoptotic protease activating factor 3; apoptotic protease MCH-6; Apoptotic protease-activating factor 3; AW493809; cas9; CASP 9; CASP9; CASP-9; Casp9_v1; Casp-9-CTD; caspase 9; caspase 9, apoptosis-related cysteine peptidase; caspase 9, apoptosis-related cysteine protease; Caspase9; caspase-9; caspase-9 dominant negative form; Caspase-9 precursor; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; caspase-9-carboxyl-terminal divergent; CTD; Ice-Lap6; ICE-like apoptotic protease 6; Mch6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9; RP11-265F14.3
Host Species: Mouse
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 12371, 842
Content And Storage: -20°C
Form: Liquid
Antigen:
Caspase 9
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.:
P55211, Q8C3Q9
Gene Symbols:
CASP9
Immunogen:
Ala331-Leu411 (Accession P55211), with N-terminal His Tag
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
C7
Conjugate:
Unconjugated
Gene:
CASP9
Gene Alias:
25 kDa caspase-9 dominant negative protein; AI115399; APAF3; APAF-3; apoptotic protease activating factor 3; apoptotic protease MCH-6; Apoptotic protease-activating factor 3; AW493809; cas9; CASP 9; CASP9; CASP-9; Casp9_v1; Casp-9-CTD; caspase 9; caspase 9, apoptosis-related cysteine peptidase; caspase 9, apoptosis-related cysteine protease; Caspase9; caspase-9; caspase-9 dominant negative form; Caspase-9 precursor; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; caspase-9-carboxyl-terminal divergent; CTD; Ice-Lap6; ICE-like apoptotic protease 6; Mch6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9; RP11-265F14.3
Host Species:
Mouse
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
12371, 842
Content And Storage:
-20°C
Form:
Liquid
Antigen: Caspase 9
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.: P55211, Q8C3Q9
Gene Symbols: CASP9
Immunogen: Ala331-Leu411 (Accession P55211), with N-terminal His Tag
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2b κ
Applications: Immunohistochemistry (Paraffin)
Clone: C7
Conjugate: Unconjugated
Gene: CASP9
Gene Alias: 25 kDa caspase-9 dominant negative protein; AI115399; APAF3; APAF-3; apoptotic protease activating factor 3; apoptotic protease MCH-6; Apoptotic protease-activating factor 3; AW493809; cas9; CASP 9; CASP9; CASP-9; Casp9_v1; Casp-9-CTD; caspase 9; caspase 9, apoptosis-related cysteine peptidase; caspase 9, apoptosis-related cysteine protease; Caspase9; caspase-9; caspase-9 dominant negative form; Caspase-9 precursor; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; caspase-9-carboxyl-terminal divergent; CTD; Ice-Lap6; ICE-like apoptotic protease 6; Mch6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9; RP11-265F14.3
Host Species: Mouse
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 12371, 842
Content And Storage: -20°C
Form: Liquid
Antigen:
Caspase 9
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.:
P55211, Q8C3Q9
Gene Symbols:
CASP9
Immunogen:
Ala331-Leu411 (Accession P55211), with N-terminal His Tag
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
C7
Conjugate:
Unconjugated
Gene:
CASP9
Gene Alias:
25 kDa caspase-9 dominant negative protein; AI115399; APAF3; APAF-3; apoptotic protease activating factor 3; apoptotic protease MCH-6; Apoptotic protease-activating factor 3; AW493809; cas9; CASP 9; CASP9; CASP-9; Casp9_v1; Casp-9-CTD; caspase 9; caspase 9, apoptosis-related cysteine peptidase; caspase 9, apoptosis-related cysteine protease; Caspase9; caspase-9; caspase-9 dominant negative form; Caspase-9 precursor; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; caspase-9-carboxyl-terminal divergent; CTD; Ice-Lap6; ICE-like apoptotic protease 6; Mch6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9; RP11-265F14.3
Host Species:
Mouse
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
12371, 842
Content And Storage:
-20°C
Form:
Liquid
Antigen: Cardiac Troponin I
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.: P19429
Gene Symbols: TNNI3
Immunogen: Recombinant protein Troponin C Type 1, Slow. The antigen corresponds to amino acid range 1-161 of the target protein.
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b κ
Applications: Western Blot
Clone: C5
Conjugate: Unconjugated
Gene: TNNI3
Gene Alias: alternatively spliced; cardiac ankyrin repeat kinase; Cardiac muscle troponin T; cardiac troponin I; cardiac troponin I isoform; cardiac troponin I-interacting kinase; cardiac troponin T; cardiac troponin T isoform 1; cardiac troponin T isoform 2; cardiac troponin T2; cardiomyopathy, dilated 1D (autosomal dominant); cardiomyopathy, dilated 2A (autosomal recessive); cardiomyopathy, hypertrophic 2; CARK; CCDD; CMD1D; CMD1FF; CMD2A; CMH2; CMH7; CMPD2; cTnI; cTnT; Ctt; CTTG; D830019J24Rik; LVNC6; MGC116817; RATCTTG; RCM1; RCM3; Serine/threonine-protein kinase TNNI3K; Tn1; TnI; TNNC1; Tnni3; TNNI3 interacting kinase; TNNI3-interacting kinase; TNNI3K; tnni3k {ECO:0000250; TNNT2; Tnnt3; TnTc; Tpn1; troponin 1, type 3; troponin I type 3 (cardiac); troponin I, cardiac 3; troponin I, cardiac muscle; troponin I, cardiac muscle-like; troponin I3, cardiac type; Troponin T cardiac; troponin T cardiac isoform; troponin T isoform 1; troponin T isoform 2; troponin T splicing mutant isoform 1; troponin
Host Species: Mouse
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 7137
Content And Storage: -20°C
Form: Liquid
Antigen:
Cardiac Troponin I
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.:
P19429
Gene Symbols:
TNNI3
Immunogen:
Recombinant protein Troponin C Type 1, Slow. The antigen corresponds to amino acid range 1-161 of the target protein.
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b κ
Applications:
Western Blot
Clone:
C5
Conjugate:
Unconjugated
Gene:
TNNI3
Gene Alias:
alternatively spliced; cardiac ankyrin repeat kinase; Cardiac muscle troponin T; cardiac troponin I; cardiac troponin I isoform; cardiac troponin I-interacting kinase; cardiac troponin T; cardiac troponin T isoform 1; cardiac troponin T isoform 2; cardiac troponin T2; cardiomyopathy, dilated 1D (autosomal dominant); cardiomyopathy, dilated 2A (autosomal recessive); cardiomyopathy, hypertrophic 2; CARK; CCDD; CMD1D; CMD1FF; CMD2A; CMH2; CMH7; CMPD2; cTnI; cTnT; Ctt; CTTG; D830019J24Rik; LVNC6; MGC116817; RATCTTG; RCM1; RCM3; Serine/threonine-protein kinase TNNI3K; Tn1; TnI; TNNC1; Tnni3; TNNI3 interacting kinase; TNNI3-interacting kinase; TNNI3K; tnni3k {ECO:0000250; TNNT2; Tnnt3; TnTc; Tpn1; troponin 1, type 3; troponin I type 3 (cardiac); troponin I, cardiac 3; troponin I, cardiac muscle; troponin I, cardiac muscle-like; troponin I3, cardiac type; Troponin T cardiac; troponin T cardiac isoform; troponin T isoform 1; troponin T isoform 2; troponin T splicing mutant isoform 1; troponin
Host Species:
Mouse
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
7137
Content And Storage:
-20°C
Form:
Liquid
Antigen: MYH7
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.: P12883
Gene Symbols: Myh7
Immunogen: Ala1777-Glu1935 (Accession P12883), with N-terminal His Tag
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Applications: Western Blot
Clone: C1
Conjugate: Unconjugated
Gene: Myh7
Gene Alias: beta cardiac myosin heavy chain; beta myosin heavy chain; beta-MHC; beta-myosin; beta-myosin heavy chain; beta-myosin-heavy-chain; B-MHC; cardiac muscle myosin heavy chain 7 beta; cardiac myosin heavy chain beta isoform; CMD1S; CMH1; LOC100727138; mg:cb02g011; MPD1; Myh7; MYH-beta/slow; MyHC-alpha; Myhcb; Myhc-b; myHC-beta; MyHC-I; MyHC-slow; myopathy, distal 1; myosin beta heavy chain; myosin heavy chain 1; myosin heavy chain 7; myosin heavy chain cardiac alpha; myosin heavy chain polypeptide 7 cardiac muscle fetal; myosin heavy chain slow; myosin heavy chain slow isoform; myosin heavy chain slow type 1 (beta cardiac); myosin heavy chain, cardiac muscle beta isoform; myosin heavy chain, cardiac muscle, fetal; myosin heavy chain, polypeptide 7; myosin, heavy chain 7, cardiac muscle, beta; myosin, heavy polypeptide 7, cardiac muscle, beta; myosin-7; rhabdomyosarcoma antigen MU-RMS-40.7A; slow myosin heavy chain; smyhc3; SPMD; SPMM; type slow/beta myosin heavy chain; Unknown (protein for
Host Species: Mouse
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 4625
Content And Storage: -20°C
Form: Liquid
Antigen:
MYH7
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.:
P12883
Gene Symbols:
Myh7
Immunogen:
Ala1777-Glu1935 (Accession P12883), with N-terminal His Tag
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
C1
Conjugate:
Unconjugated
Gene:
Myh7
Gene Alias:
beta cardiac myosin heavy chain; beta myosin heavy chain; beta-MHC; beta-myosin; beta-myosin heavy chain; beta-myosin-heavy-chain; B-MHC; cardiac muscle myosin heavy chain 7 beta; cardiac myosin heavy chain beta isoform; CMD1S; CMH1; LOC100727138; mg:cb02g011; MPD1; Myh7; MYH-beta/slow; MyHC-alpha; Myhcb; Myhc-b; myHC-beta; MyHC-I; MyHC-slow; myopathy, distal 1; myosin beta heavy chain; myosin heavy chain 1; myosin heavy chain 7; myosin heavy chain cardiac alpha; myosin heavy chain polypeptide 7 cardiac muscle fetal; myosin heavy chain slow; myosin heavy chain slow isoform; myosin heavy chain slow type 1 (beta cardiac); myosin heavy chain, cardiac muscle beta isoform; myosin heavy chain, cardiac muscle, fetal; myosin heavy chain, polypeptide 7; myosin, heavy chain 7, cardiac muscle, beta; myosin, heavy polypeptide 7, cardiac muscle, beta; myosin-7; rhabdomyosarcoma antigen MU-RMS-40.7A; slow myosin heavy chain; smyhc3; SPMD; SPMM; type slow/beta myosin heavy chain; Unknown (protein for
Host Species:
Mouse
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
4625
Content And Storage:
-20°C
Form:
Liquid