PIMA544002
CD18 Monoclonal Antibody (MEM-148), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA544002-Each-of-1 | In Stock | ₹ 22,887.30 |
PIMA544002 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 22,887.30
GST (18%): ₹ 4,119.714
Total Price: ₹ 27,007.014
Antigen
CD18
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.
P05107
Gene Symbols
ITGB2
Immunogen
Peripheral blood mononuclear cells
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Immunoprecipitation, Western Blot
Clone
MEM-148
Conjugate
Unconjugated
Gene
ITGB2
Gene Alias
2E6; AI528527; antigen CD18; B-2 integrin; CD18; CD18 leukocyte adhesion molecule; CD18 subunit; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; complement receptor C3 subunit beta; integrin beta 2; integrin beta chain, beta 2; integrin beta-2; integrin subunit beta 2; integrin, beta 2; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit); integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGB2; LAD; LCAMB; Leu-CAM receptor; leukocyte cell adhesion molecule CD18; leukocyte surface protein; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; Lfa1; LFA-1; lymphocyte function associated antigen 1; MAC-1; Mac-1 beta; macrophage antigen 1 (mac-1) beta subunit); macrophage antigen-1 beta; MF17; MFI7
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
3689
Content And Storage
4° C, do not freeze
Form
Liquid
Related Products
Description
- Western Blot: non-reducing conditions
- CD18 integrin beta 2 subunit is a 90 kDa type I transmembrane protein expressed on all leucocytes
- CD18 can combine with integrin molecules CD11a-c to form heterodimers at the cell surface, and these heterodimers are known to participate in the process of cell adhesion as well as cell-surface mediated signaling
- CD18 forms heterodimers with four types of CD11 molecule to constitute leukocyte (beta2) integrins: alphaLbeta2 (CD11a/CD18, LFA-1), alphaMbeta2 (CD11b/CD18, Mac-1, CR3), alphaXbeta2 (CD11c/CD18) and alphaDbeta2 (CD11d/CD18)
- In most cases, the response mediated by the integrin is a composite of the functions of its individual subunits, and these integrins are essential for proper leukocyte migration, mediating intercellular contacts
- Absence of CD18 leads to leukocyte adhesion deficiency-1, severe reduction of CD18 expression leads to the development of a psoriasiform skin disease
- CD18 is also a target of Mannheimia (Pasteurella) haemolytica leukotoxin and is sufficient to mediate leukotoxin-mediated cytolysis
- Defects in the CD18 gene are the cause of leukocyte adhesion deficiency type I (LAD1)
- Two transcript variants encoding the CD18 protein have been identified.
Compare Similar Items
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Antigen: CD18
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 15mM sodium azide; pH 7.4
Gene Accession No.: P05107
Gene Symbols: ITGB2
Immunogen: Peripheral blood mononuclear cells
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunoprecipitation, Western Blot
Clone: MEM-148
Conjugate: Unconjugated
Gene: ITGB2
Gene Alias: 2E6; AI528527; antigen CD18; B-2 integrin; CD18; CD18 leukocyte adhesion molecule; CD18 subunit; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; complement receptor C3 subunit beta; integrin beta 2; integrin beta chain, beta 2; integrin beta-2; integrin subunit beta 2; integrin, beta 2; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit); integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGB2; LAD; LCAMB; Leu-CAM receptor; leukocyte cell adhesion molecule CD18; leukocyte surface protein; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; Lfa1; LFA-1; lymphocyte function associated antigen 1; MAC-1; Mac-1 beta; macrophage antigen 1 (mac-1) beta subunit); macrophage antigen-1 beta; MF17; MFI7
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3689
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
CD18
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
P05107
Gene Symbols:
ITGB2
Immunogen:
Peripheral blood mononuclear cells
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunoprecipitation, Western Blot
Clone:
MEM-148
Conjugate:
Unconjugated
Gene:
ITGB2
Gene Alias:
2E6; AI528527; antigen CD18; B-2 integrin; CD18; CD18 leukocyte adhesion molecule; CD18 subunit; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; complement receptor C3 subunit beta; integrin beta 2; integrin beta chain, beta 2; integrin beta-2; integrin subunit beta 2; integrin, beta 2; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit); integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGB2; LAD; LCAMB; Leu-CAM receptor; leukocyte cell adhesion molecule CD18; leukocyte surface protein; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; Lfa1; LFA-1; lymphocyte function associated antigen 1; MAC-1; Mac-1 beta; macrophage antigen 1 (mac-1) beta subunit); macrophage antigen-1 beta; MF17; MFI7
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3689
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: CD46
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 15mM sodium azide; pH 7.4
Gene Accession No.: P15529, Q6VE48
Gene Symbols: CD46
Immunogen: HPB-ALL human T cell line
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Bovine, Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunoprecipitation, Western Blot
Clone: MEM-258
Conjugate: Unconjugated
Gene: CD46
Gene Alias: AHUS2; antigen identified by monoclonal antibody TRA-2-10; brain microvascular membrane cofactor; brain microvascular membrane cofactor protein CD46; Cd46; CD46 antigen, complement regulatory protein; CD46 complement regulatory protein; CD46 molecule; CD46 molecule, complement regulatory protein; CD46 splice variant; complement membrane cofactor protein; complement regulatory protein; Mcp; MCP; complement activation regulator; measles virus receptor; membrane cofactor protein; membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen); membrane cofactor protein variant 10; membrane cofactor protein variant 7; membrane cofactor protein variant 8; membrane cofactor protein variant 9; MGC26544; MIC10; soluble membrane cofactor protein variant 11; soluble membrane cofactor protein variant 12; soluble membrane cofactor protein variant 13; TLX; TRA2.10; trophoblast leucocyte common antigen; trophoblast leukocyte common antigen; trophoblast-lymphocyte cross-reactive antigen
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 280851, 4179
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
CD46
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
P15529, Q6VE48
Gene Symbols:
CD46
Immunogen:
HPB-ALL human T cell line
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunoprecipitation, Western Blot
Clone:
MEM-258
Conjugate:
Unconjugated
Gene:
CD46
Gene Alias:
AHUS2; antigen identified by monoclonal antibody TRA-2-10; brain microvascular membrane cofactor; brain microvascular membrane cofactor protein CD46; Cd46; CD46 antigen, complement regulatory protein; CD46 complement regulatory protein; CD46 molecule; CD46 molecule, complement regulatory protein; CD46 splice variant; complement membrane cofactor protein; complement regulatory protein; Mcp; MCP; complement activation regulator; measles virus receptor; membrane cofactor protein; membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen); membrane cofactor protein variant 10; membrane cofactor protein variant 7; membrane cofactor protein variant 8; membrane cofactor protein variant 9; MGC26544; MIC10; soluble membrane cofactor protein variant 11; soluble membrane cofactor protein variant 12; soluble membrane cofactor protein variant 13; TLX; TRA2.10; trophoblast leucocyte common antigen; trophoblast leukocyte common antigen; trophoblast-lymphocyte cross-reactive antigen
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
280851, 4179
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: TCR V beta 5.3
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 15mM sodium azide; pH 7.4
Gene Accession No.: 0
Gene Symbols: TRB
Immunogen: Human thymoma cell line HPB-ALL
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Flow Cytometry, Immunoprecipitation, Western Blot
Clone: MEM-262
Conjugate: Unconjugated
Gene: TRB
Gene Alias: T cell receptor beta locus; TCRB; TRB; TRB@
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 6957
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
TCR V beta 5.3
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
0
Gene Symbols:
TRB
Immunogen:
Human thymoma cell line HPB-ALL
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry, Immunoprecipitation, Western Blot
Clone:
MEM-262
Conjugate:
Unconjugated
Gene:
TRB
Gene Alias:
T cell receptor beta locus; TCRB; TRB; TRB@
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
6957
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: CD235a
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 15mM sodium azide; pH 7.4
Gene Accession No.: P02724
Gene Symbols: GYPA
Immunogen: Synthetic peptide (Human, N-terminal)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Agglutination, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone: HIR2
Conjugate: Unconjugated
Gene: GYPA
Gene Alias: AI853584; CD235; CD235a; erythroid-lineage-specific membrane sialoglycoprotein; glycophorin A; glycophorin A (MN blood group); glycophorin A (MNS blood group); glycophorin A, GPA; glycophorin Erik; glycophorin MiI; glycophorin MiV; glycophorin SAT; glycophorin Sta type C; glycophorin-A; GPA; GPErik; GPSAT; Gypa; HGNC:4702; HGpMiV; HGpMiX; HGpMiXI; HGpSta(C); HGpStaC; Mi.V glycoprotein; Mi.V glycoprotein (24 AA); MN; MN sialoglycoprotein; MNS; PAS-2; recombinant glycophorin A-B Miltenberger-DR; sialoglycoprotein alpha
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2993
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
CD235a
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
P02724
Gene Symbols:
GYPA
Immunogen:
Synthetic peptide (Human, N-terminal)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Agglutination, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone:
HIR2
Conjugate:
Unconjugated
Gene:
GYPA
Gene Alias:
AI853584; CD235; CD235a; erythroid-lineage-specific membrane sialoglycoprotein; glycophorin A; glycophorin A (MN blood group); glycophorin A (MNS blood group); glycophorin A, GPA; glycophorin Erik; glycophorin MiI; glycophorin MiV; glycophorin SAT; glycophorin Sta type C; glycophorin-A; GPA; GPErik; GPSAT; Gypa; HGNC:4702; HGpMiV; HGpMiX; HGpMiXI; HGpSta(C); HGpStaC; Mi.V glycoprotein; Mi.V glycoprotein (24 AA); MN; MN sialoglycoprotein; MNS; PAS-2; recombinant glycophorin A-B Miltenberger-DR; sialoglycoprotein alpha
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2993
Content And Storage:
4° C, do not freeze
Form:
Liquid