PIMA544029
CD178 Monoclonal Antibody (NOK-1), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA544029-Each-of-1 | In Stock | ₹ 22,801.74 |
PIMA544029 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 22,801.74
GST (18%): ₹ 4,104.313
Total Price: ₹ 26,906.053
Antigen
CD178
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.
P48023
Gene Symbols
Faslg
Immunogen
L5178Y mouse T lymphoma cells expressing recombinant human CD178
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
NOK-1
Conjugate
Unconjugated
Gene
Faslg
Gene Alias
ADAM10-processed FasL form; ALPS1B; APL; Apoptosis (APO 1) antigen ligand 1; apoptosis (APO-1) antigen ligand 1; Apoptosis (APO-1) antigen ligand 1 (Fas antigen ligand); apoptosis antigen ligand; APT1LG1; APTL; CD178; CD178 antigen; CD95 ligand; CD95 ligand protein;Generalized lymphoproliferative disease (Gld); Cd95l; CD95-L; CD95L protein; fas antigen ligand; Fas ligand; Fas ligand (TNF superfamily, member 6); Fasl; Fas-L; FasL ICD; FasL intracellular domain; Faslg; Fas-LG; generalized lymphoproliferative disease; gld; mutant tumor necrosis factor family member 6; Receptor-binding FasL ectodomain; sFasL; Soluble Fas ligand; soluble form; SPA; SPPL2A-processed FasL form; TNFL; Tnfsf6; TNLG1A; Tumor necrosis factor (ligand) superfamily member 6; Tumor necrosis factor (ligand) superfamily member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor (ligand) superfamily, member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor ligand; tumor necrosis factor ligand 1A; tumor necrosis factor ligand superfamily member 6; Tumor necrosis factor ligand superfamily member 6 (TNFL6 / TNFSF6); Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
356
Content And Storage
4° C, do not freeze
Form
Liquid
Related Products
Description
- CD178 (Fas ligand, FasL) is a type-II-membrane protein, whose N-terminus is in the cytoplasm and its C-terminal region extends into the extracellular space
- Its receptor, FasR, is a cell-surface-type-I-membrane protein and a member of the tumor necrosis factor (TNF) and nerve growth factor (NGF) receptor family
- As a member of the TNF-cytokine family CD178 induces apoptosis when interacting with FasR
- CD178 may exist as either membrane bound (45 kD) or soluble forms (26 kD)
- The soluble protein can be released from cells upon cleavage by metalloproteinases
- Binding of CD178 to Fas leads to oligomerization of the receptor and triggers apoptotic cell death through the interaction of other proteins
- CD178 is predominantly expressed in activated T-lymphocytes and natural killer (NK) cells also it is expressed in the tissues of immune-privilege sites such as testis and eye
- CD178 expression is also reported in various tissues as thymus, liver, ovary, lung, heart and kidney
- It is assumed that induction of apoptosis through CD178 is predominantly involved in anti-viral immune responses
- CD178 is a cell surface molecule belonging to the tumor necrosis factor family, binds to its receptor Fas, thus inducing apoptosis
- Various cells express FAS, where CD178 is expressed predominantly on activated T cells
- FAS and CD178 are involved in the down-regulation of immune reactions as well as T cell-mediated cytotoxicity
- CD178 concentration has also been shown to be associated with atherosclerosis and inflammatory disease, in patients with hypertension
- The Fas/ CD178 system has been shown to play a role in a number of human diseases, for example AIDS, hepatitis or cancer.
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Antigen: CD178
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 15mM sodium azide; pH 7.4
Gene Accession No.: P48023
Gene Symbols: Faslg
Immunogen: L5178Y mouse T lymphoma cells expressing recombinant human CD178
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: NOK-1
Conjugate: Unconjugated
Gene: Faslg
Gene Alias: ADAM10-processed FasL form; ALPS1B; APL; Apoptosis (APO 1) antigen ligand 1; apoptosis (APO-1) antigen ligand 1; Apoptosis (APO-1) antigen ligand 1 (Fas antigen ligand); apoptosis antigen ligand; APT1LG1; APTL; CD178; CD178 antigen; CD95 ligand; CD95 ligand protein;Generalized lymphoproliferative disease (Gld); Cd95l; CD95-L; CD95L protein; fas antigen ligand; Fas ligand; Fas ligand (TNF superfamily, member 6); Fasl; Fas-L; FasL ICD; FasL intracellular domain; Faslg; Fas-LG; generalized lymphoproliferative disease; gld; mutant tumor necrosis factor family member 6; Receptor-binding FasL ectodomain; sFasL; Soluble Fas ligand; soluble form; SPA; SPPL2A-processed FasL form; TNFL; Tnfsf6; TNLG1A; Tumor necrosis factor (ligand) superfamily member 6; Tumor necrosis factor (ligand) superfamily member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor (ligand) superfamily, member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor ligand; tumor necrosis factor ligand 1A; tumor necrosis factor ligand superfamily member 6; Tumor necrosis factor ligand superfamily member 6 (TNFL6 / TNFSF6); Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 356
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
CD178
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
P48023
Gene Symbols:
Faslg
Immunogen:
L5178Y mouse T lymphoma cells expressing recombinant human CD178
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
NOK-1
Conjugate:
Unconjugated
Gene:
Faslg
Gene Alias:
ADAM10-processed FasL form; ALPS1B; APL; Apoptosis (APO 1) antigen ligand 1; apoptosis (APO-1) antigen ligand 1; Apoptosis (APO-1) antigen ligand 1 (Fas antigen ligand); apoptosis antigen ligand; APT1LG1; APTL; CD178; CD178 antigen; CD95 ligand; CD95 ligand protein;Generalized lymphoproliferative disease (Gld); Cd95l; CD95-L; CD95L protein; fas antigen ligand; Fas ligand; Fas ligand (TNF superfamily, member 6); Fasl; Fas-L; FasL ICD; FasL intracellular domain; Faslg; Fas-LG; generalized lymphoproliferative disease; gld; mutant tumor necrosis factor family member 6; Receptor-binding FasL ectodomain; sFasL; Soluble Fas ligand; soluble form; SPA; SPPL2A-processed FasL form; TNFL; Tnfsf6; TNLG1A; Tumor necrosis factor (ligand) superfamily member 6; Tumor necrosis factor (ligand) superfamily member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor (ligand) superfamily, member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor ligand; tumor necrosis factor ligand 1A; tumor necrosis factor ligand superfamily member 6; Tumor necrosis factor ligand superfamily member 6 (TNFL6 / TNFSF6); Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
356
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: CD41
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 15mM sodium azide; pH 7.4
Gene Accession No.: Q9QUM0
Gene Symbols: Itga2b
Immunogen: Murine platelets
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1 κ
Applications: ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone: MWReg30
Conjugate: Unconjugated
Gene: Itga2b
Gene Alias: AI172977; alpha IIb; alphaIIb; alphaIIb protein; BDPLT16; BDPLT2; CD41; CD41B; form 1; form 2; GP IIb; GP2B; GPalpha IIb; GPIIb; GT; GTA; HPA3; integrin alpha 2b; integrin alpha 2b (Cd41b); integrin alpha-IIb; Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2; integrin subunit alpha 2b; integrin subunit alpha IIb; integrin, alpha 2B; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); ITGA2B; ITGAB; platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb; platelet glycoprotein IIb of IIb/II Ia complex; platelet glycoprotein IIb of IIb/IIIa complex; platelet membrane glycoprotein IIb; platelet-specific antigen BAK; PPP1R93; protein phosphatase 1, regulatory subunit 93
Host Species: Rat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 16399
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
CD41
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
Q9QUM0
Gene Symbols:
Itga2b
Immunogen:
Murine platelets
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone:
MWReg30
Conjugate:
Unconjugated
Gene:
Itga2b
Gene Alias:
AI172977; alpha IIb; alphaIIb; alphaIIb protein; BDPLT16; BDPLT2; CD41; CD41B; form 1; form 2; GP IIb; GP2B; GPalpha IIb; GPIIb; GT; GTA; HPA3; integrin alpha 2b; integrin alpha 2b (Cd41b); integrin alpha-IIb; Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2; integrin subunit alpha 2b; integrin subunit alpha IIb; integrin, alpha 2B; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); ITGA2B; ITGAB; platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb; platelet glycoprotein IIb of IIb/II Ia complex; platelet glycoprotein IIb of IIb/IIIa complex; platelet membrane glycoprotein IIb; platelet-specific antigen BAK; PPP1R93; protein phosphatase 1, regulatory subunit 93
Host Species:
Rat
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
16399
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: P-Glycoprotein
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 15mM sodium azide; pH 7.4
Gene Accession No.: P08183
Gene Symbols: ABCB1
Immunogen: NIH 3T3 cells transfected with human CD243 (MDR-1) cDNA
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a κ
Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone: UIC2
Conjugate: Unconjugated
Gene: ABCB1
Gene Alias: ABC superfamily; P-glycoprotein; ABC20; ABCB1; Abcb1a; Abcb1b; Abcb4; ATP binding cassette subfamily B member 1; ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1); ATP-binding cassette sub-family B member 1; ATP-binding cassette sub-family B member 1A; ATP-binding cassette sub-family B member 1B; ATP-binding cassette transporter subfamily B, member 1; ATP-binding cassette, sub-family B (MDR/TAP), member 1; ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1); ATP-binding cassette, subfamily B (MDR/TAP), member 1A; ATP-binding cassette, sub-family B (MDR/TAP), member 1A; ATP-binding cassette, subfamily B (MDR/TAP), member 1B; ATP-binding cassette, sub-family B (MDR/TAP), member 1B; ATP-binding cassette, sub-family B (MDR/TAP), member 4; ATP-binding cassette, subfamily B, member 1A; ATP-binding cassette, subfamily B, member 1B; ATP-dependent translocase ABCB1; ATP-dependent translocase ABCB1; multidrug resistance protein 1; bovine p-glycoprotein; CD243; CLCS; colchicin sensitivity; doxorubicin resistance; ecotropic viral integration site 32; Evi32; GP170; mdr; Mdr1; MDR1A; Mdr1b; Mdr3; mdr-3; multi-drug resistance 3; multidrug resistance p-glycoprotein; multidrug resistance protein 1; Multidrug resistance protein 1A; multidrug resistance protein 1B; Multidrug resistance protein 2; multidrug resistance protein 3; multidrug resistance protein MDR1; multiple drug resistant 1a; P glycoprotein 1; P glycoprotein 3; P-glycoprotein; P-glycoprotein 1; P-glycoprotein 2; P-glycoprotein 3; P-glycoprotein/multidrug resistance 1; Pgp; p-gp; PGP1; PGP2; PGY1; Pgy-1; Pgy1-1; PGY2; Pgy3; Pgy-3; Phospholipid transporter ABCB1
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5243
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
P-Glycoprotein
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
P08183
Gene Symbols:
ABCB1
Immunogen:
NIH 3T3 cells transfected with human CD243 (MDR-1) cDNA
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a κ
Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone:
UIC2
Conjugate:
Unconjugated
Gene:
ABCB1
Gene Alias:
ABC superfamily; P-glycoprotein; ABC20; ABCB1; Abcb1a; Abcb1b; Abcb4; ATP binding cassette subfamily B member 1; ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1); ATP-binding cassette sub-family B member 1; ATP-binding cassette sub-family B member 1A; ATP-binding cassette sub-family B member 1B; ATP-binding cassette transporter subfamily B, member 1; ATP-binding cassette, sub-family B (MDR/TAP), member 1; ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1); ATP-binding cassette, subfamily B (MDR/TAP), member 1A; ATP-binding cassette, sub-family B (MDR/TAP), member 1A; ATP-binding cassette, subfamily B (MDR/TAP), member 1B; ATP-binding cassette, sub-family B (MDR/TAP), member 1B; ATP-binding cassette, sub-family B (MDR/TAP), member 4; ATP-binding cassette, subfamily B, member 1A; ATP-binding cassette, subfamily B, member 1B; ATP-dependent translocase ABCB1; ATP-dependent translocase ABCB1; multidrug resistance protein 1; bovine p-glycoprotein; CD243; CLCS; colchicin sensitivity; doxorubicin resistance; ecotropic viral integration site 32; Evi32; GP170; mdr; Mdr1; MDR1A; Mdr1b; Mdr3; mdr-3; multi-drug resistance 3; multidrug resistance p-glycoprotein; multidrug resistance protein 1; Multidrug resistance protein 1A; multidrug resistance protein 1B; Multidrug resistance protein 2; multidrug resistance protein 3; multidrug resistance protein MDR1; multiple drug resistant 1a; P glycoprotein 1; P glycoprotein 3; P-glycoprotein; P-glycoprotein 1; P-glycoprotein 2; P-glycoprotein 3; P-glycoprotein/multidrug resistance 1; Pgp; p-gp; PGP1; PGP2; PGY1; Pgy-1; Pgy1-1; PGY2; Pgy3; Pgy-3; Phospholipid transporter ABCB1
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5243
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: CD206
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 15mM sodium azide; pH 7.4
Gene Accession No.: P22897
Gene Symbols: Mrc1
Immunogen: Purified human mannose receptor
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone: 15-2
Conjugate: Unconjugated
Gene: Mrc1
Gene Alias: AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4360
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
CD206
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
P22897
Gene Symbols:
Mrc1
Immunogen:
Purified human mannose receptor
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone:
15-2
Conjugate:
Unconjugated
Gene:
Mrc1
Gene Alias:
AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4360
Content And Storage:
4° C, do not freeze
Form:
Liquid