PIMA544065
CD86 Monoclonal Antibody (BU63), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA544065-Each-of-1 | In Stock | ₹ 26,438.04 |
PIMA544065 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 26,438.04
GST (18%): ₹ 4,758.847
Total Price: ₹ 31,196.887
Antigen
CD86
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
P42081
Gene Symbols
CD86
Immunogen
B-lymphoblastoid cell line ARH 77
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone
BU63
Conjugate
Unconjugated
Gene
CD86
Gene Alias
activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
942
Content And Storage
4° C, do not freeze
Form
Liquid
Related Products
Description
- Functional application: The antibody blocks mixed lymphocyte reaction (MLR) and binding of soluble CTLA-4 (CD152)-mulg fusion protein to CD86 (B7-2) CD86 is one of two ligands (the other CD80) for CTLA4 and CD28
- CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation
- Antigen presentation in the absence of sufficient co-stimulation involving CD86/CD80 can induce tolerance
- CD80 appears to play a role distinct from CD80 in T helper cell differentiation
- CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily
- The CD86 protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4
- Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell
- Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response
- Alternative splicing results in two transcript variants encoding different isoforms of CD86
- Additional transcript variants have been described for CD86, but their full-length sequences have not been determined
- Diseases associated with CD86 dysfunction include gallbladder squamous cell carcinoma and myocarditis.
Compare Similar Items
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Antigen: CD86
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative; pH 7.4
Gene Accession No.: P42081
Gene Symbols: CD86
Immunogen: B-lymphoblastoid cell line ARH 77
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone: BU63
Conjugate: Unconjugated
Gene: CD86
Gene Alias: activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 942
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
CD86
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative; pH 7.4
Gene Accession No.:
P42081
Gene Symbols:
CD86
Immunogen:
B-lymphoblastoid cell line ARH 77
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone:
BU63
Conjugate:
Unconjugated
Gene:
CD86
Gene Alias:
activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
942
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: CD81
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative; pH 7.4
Gene Accession No.: P60033
Gene Symbols: CD81
Immunogen: MOLT-4 (human T-ALL cell line)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Feline, Human, Rabbit
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: M38
Conjugate: Unconjugated
Gene: CD81
Gene Alias: 26 kDa cell surface protein TAPA-1; CD 81 antigen; Cd81; CD81 antigen; CD81 antigen (target of antiproliferative antibody 1); CD81 molecule; CVID6; S5.7; Tapa1; Tapa-1; Target of the antiproliferative antibody 1; Tetraspanin28; tetraspanin-28; Tspan28; Tspan-28
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 101093144, 975
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
CD81
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative; pH 7.4
Gene Accession No.:
P60033
Gene Symbols:
CD81
Immunogen:
MOLT-4 (human T-ALL cell line)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Feline, Human, Rabbit
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
M38
Conjugate:
Unconjugated
Gene:
CD81
Gene Alias:
26 kDa cell surface protein TAPA-1; CD 81 antigen; Cd81; CD81 antigen; CD81 antigen (target of antiproliferative antibody 1); CD81 molecule; CVID6; S5.7; Tapa1; Tapa-1; Target of the antiproliferative antibody 1; Tetraspanin28; tetraspanin-28; Tspan28; Tspan-28
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
101093144, 975
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: CD180
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative; pH 7.4
Gene Accession No.: Q99467
Gene Symbols: Cd180
Immunogen: Human tonsillar B cells
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Applications: Flow Cytometry, Functional Assay, Immunoprecipitation
Clone: G28-8
Conjugate: Unconjugated
Gene: Cd180
Gene Alias: CD180; CD180 antigen; CD180 molecule; F630107B15; LY64; Ly78; Ly-78; lymphocyte antigen 64; Lymphocyte antigen 78; lymphocyte antigen-64, radioprotective, 105kDa; MGC126233; MGC126234; radioprotective 105 kDa protein; RP105
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4064
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
CD180
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative; pH 7.4
Gene Accession No.:
Q99467
Gene Symbols:
Cd180
Immunogen:
Human tonsillar B cells
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Functional Assay, Immunoprecipitation
Clone:
G28-8
Conjugate:
Unconjugated
Gene:
Cd180
Gene Alias:
CD180; CD180 antigen; CD180 molecule; F630107B15; LY64; Ly78; Ly-78; lymphocyte antigen 64; Lymphocyte antigen 78; lymphocyte antigen-64, radioprotective, 105kDa; MGC126233; MGC126234; radioprotective 105 kDa protein; RP105
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4064
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: TCR alpha/beta
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative; pH 7.4
Gene Accession No.: 0
Gene Symbols: LOC290071, Tcrb
Immunogen: Rat T blasts and erythrocytes
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG1 κ
Applications: Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: R73
Conjugate: Unconjugated
Gene: Tcrb
Gene Alias: FLJ22602; IMD7; LOC290071; MGC117436; MGC22624; MGC23964; MGC71411; RATTCB; RATTCBC1; RGD1359684; similar to RIKEN cDNA A430107P09 gene; T cell receptor beta locus; T3/TCR complex; TCB; TCBC1; t-cell antigen receptor; T-cell receptor alpha constant; T-cell receptor beta chain; T-cell receptor V alpha; tcr alpha; TCR alpha/ beta; TCR beta; TCRA; Tcrb; TRA; Tra29; TRAC; TRB; TRB@; TRCA
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 24820, 290071
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
TCR alpha/beta
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative; pH 7.4
Gene Accession No.:
0
Gene Symbols:
LOC290071, Tcrb
Immunogen:
Rat T blasts and erythrocytes
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
R73
Conjugate:
Unconjugated
Gene:
Tcrb
Gene Alias:
FLJ22602; IMD7; LOC290071; MGC117436; MGC22624; MGC23964; MGC71411; RATTCB; RATTCBC1; RGD1359684; similar to RIKEN cDNA A430107P09 gene; T cell receptor beta locus; T3/TCR complex; TCB; TCBC1; t-cell antigen receptor; T-cell receptor alpha constant; T-cell receptor beta chain; T-cell receptor V alpha; tcr alpha; TCR alpha/ beta; TCR beta; TCRA; Tcrb; TRA; Tra29; TRAC; TRB; TRB@; TRCA
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
24820, 290071
Content And Storage:
4° C, do not freeze
Form:
Liquid