PIMA544121

TCR V gamma 4 Monoclonal Antibody (4A11.904), PE, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA544121-Each-of-1 In Stock ₹ 40,555.44

PIMA544121 - Each of 1

₹ 40,555.44

In Stock

Quantity

1

Base Price: ₹ 40,555.44

GST (18%): ₹ 7,299.979

Total Price: ₹ 47,855.419

Antigen

TCR V gamma 4

Classification

Monoclonal

Conjugate

PE

Gene

TRG

Gene Alias

PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Host Species

Mouse

Purification Method

Size-exclusion chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6965

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

4A11.904

Formulation

PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.

0

Gene Symbols

TRG

Immunogen

human T cells

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response
  • TCR recognition of self-peptides has been linked to autoimmune disease
  • Mutant self-peptides have been associated with tumors
  • Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome
  • Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)
  • The autoantibodies block TH1-mediated inflammatory autodestructive reactions and are believed to be a method by which the immune system compensates for disease (ref5)
  • T Cell and TCR Diversity Most human T cells express the TCR alpha-beta and either CD4 or CD8 molecule (single positive, SP)
  • A small number of T cells lack both CD4 and CD8 (double negative, DN)
  • Increased percentages of alpha-beta DN T cells have been identified in some autoimmune and immunodeficiency disorders
  • Gamma-delta T cells are primarily found within the epithelium
  • They show less TCR diversity and recognize antigens differently than alpha-beta T cells
  • Subsets of gamma-delta T cells have shown antitumor and immunoregulatory activity.

Compare Similar Items

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Img

Thermo Scientific

PIMA544121

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Antigen:
TCR V gamma 4

Classification:
Monoclonal

Conjugate:
PE

Gene:
TRG

Gene Alias:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6965

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
4A11.904

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
0

Gene Symbols:
TRG

Immunogen:
human T cells

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA544123

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Antigen:
CD41/CD61

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Gene:
ITGA2B

Gene Alias:
alphaIIb protein; antigen CD61; BDPLT16; BDPLT2; CD41; CD41B; CD61; glycoprotein GPIIb; glycoprotein GPIIIa; glycoprotein IIb; glycoprotein IIIa; GP2B; GP3A; GPalpha IIb; GPIIb; GPIIIa; GT; GTA; HPA3; INTB3; integrin; integrin alpha 2b; integrin alpha 2b precursor; Integrin alpha-2b; integrin alpha-IIb; Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2; Integrin beta; integrin beta 3; integrin beta 3 subunit; integrin beta3; integrin beta-3; integrin beta-3 subunit; integrin subunit alpha 2b; integrin subunit alpha IIb; integrin subunit beta 3; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B); integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGA2B; ITGA2B-like protein; ITGAB; ITGB3; platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb; platelet glycoprotein IIb of IIb/IIIa complex; platelet glycoprotein IIIa; platelet glycoprotein IIIa integrin subunit beta 3; platelet membrane glycoprotein IIb; Platelet membrane glycoprotein IIIa; platelet-specific antigen BAK; PPP1R93; protein phosphatase 1, regulatory subunit 93

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3674, 3690

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry

Clone:
PAC-1

Formulation:
TBS with 0.2% BSA and 15mM sodium azide; pH 8

Gene Accession No.:
P05106, P08514

Gene Symbols:
ITGA2B, ITGB3

Immunogen:
Human platelets

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgM κ

Img

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PIMA544128

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Antigen:
CD18

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Gene:
ITGB2

Gene Alias:
2E6; AI528527; antigen CD18; B-2 integrin; CD18; CD18 leukocyte adhesion molecule; CD18 subunit; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; complement receptor C3 subunit beta; integrin beta 2; integrin beta chain, beta 2; integrin beta-2; integrin subunit beta 2; integrin, beta 2; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit); integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGB2; LAD; LCAMB; Leu-CAM receptor; leukocyte cell adhesion molecule CD18; leukocyte surface protein; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; Lfa1; LFA-1; lymphocyte function associated antigen 1; MAC-1; Mac-1 beta; macrophage antigen 1 (mac-1) beta subunit); macrophage antigen-1 beta; MF17; MFI7

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
281877, 3689

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry

Clone:
IVA35

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P05107, P32592

Gene Symbols:
ITGB2

Immunogen:
Bovine leukocytes

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA544131

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Antigen:
CD300a

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Gene:
CD300A

Gene Alias:
B230315M08Rik; CD300 antigen-like family member A; Cd300a; CD300a antigen; CD300a molecule; Clm8; CLM-8; CMRF35H; CMRF-35H; CMRF35-H; CMRF35H leukocyte immunoglobulin-like receptor; CMRF35H9; CMRF-35-H9; CMRF35-H9; CMRF35HIRp60; CMRF35-like molecule 8; HSPC083; IGSF12; Immunoglobulin superfamily member 12; inhibitory receptor protein 60; IRC1; IRC1/IRC2; IRC2; IRp60; leukocyte membrane antigen; leukocyte mono-Ig-like receptor 1; Lmir1; MAIR-1; MAIR-I; MAIR-Ia; Mast cell-derived paired immunoglobulin-like receptor 1; Mcipr1; mcpir1; MMAC8; myeloid-associated immunoglobulin-like receptor 1; NK inhibitory receptor; NKRL; Pigr4; polymeric immunoglobulin receptor 4

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11314

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Clone:
MEM-260

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
Q9UGN4

Gene Symbols:
CD300A

Immunogen:
HPB human acute lymphoid leukemia cell line

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1