PIMA544197
MDMX Recombinant Rabbit Monoclonal Antibody (BL-3-2F2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA544197-Each-of-1 | In Stock | ₹ 33,881.76 |
PIMA544197 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 33,881.76
GST (18%): ₹ 6,098.717
Total Price: ₹ 39,980.477
Antigen
MDMX
Classification
Recombinant Monoclonal
Concentration
100 μg/mL
Formulation
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.
O15151
Gene Symbols
MDM4
Immunogen
Between 125 And 175
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunoprecipitation, Western Blot
Clone
BL-3-2F2
Conjugate
Unconjugated
Gene
MDM4
Gene Alias
4933417N07Rik; AA414968; AL023055; AU018793; AU021806; C85810; DKFZp781B1423; double minute 4 homolog; double minute 4 protein; double minute 4, human homolog of; p53-binding protein; HDMX; human homolog of; Mdm2-like p53-binding protein; MDM4; Mdm4 p53 binding protein homolog; MDM4 protein variant G; MDM4 protein variant Y; MDM4, p53 regulator; MDM4-related protein 1; Mdmx; MGC132766; MRP1; p53-binding protein Mdm4; Protein Mdm4; protein Mdmx; RP11-430C7.1; transformed mouse 3T3 cell double minute 4
Host Species
Rabbit
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
4194
Content And Storage
2-8°C
Form
Liquid
Related Products
Description
- The MDM2 protein is the primary regulator of p53 protein stability
- MDMX is an MDM2-related protein that inhibits MDM2-mediated degradation of p53 via distinct associations with MDM2
- The gene that encodes MDMX (also designated MDM4) is a target for amplification in malignant gliomas
- ARF interacts with MDMX to sequester MDMX within the nucleolus
- This sequestration of MDMX by ARF results in an increase in p53 transactivation
- In addition, expression of MDMX can reverse MDM2-targeted degradation of p53 while maintaining suppression of p53 transactivation
- Like MDM2, MDMX also binds p73 and stabilizes the level of p73
- Therefore, in striking contrast to p53, the half-life of p73 is increased by binding to MDM2.
Compare Similar Items
Show Difference
Antigen: MDMX
Classification: Recombinant Monoclonal
Concentration: 100 μg/mL
Formulation: BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.: O15151
Gene Symbols: MDM4
Immunogen: Between 125 And 175
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunoprecipitation, Western Blot
Clone: BL-3-2F2
Conjugate: Unconjugated
Gene: MDM4
Gene Alias: 4933417N07Rik; AA414968; AL023055; AU018793; AU021806; C85810; DKFZp781B1423; double minute 4 homolog; double minute 4 protein; double minute 4, human homolog of; p53-binding protein; HDMX; human homolog of; Mdm2-like p53-binding protein; MDM4; Mdm4 p53 binding protein homolog; MDM4 protein variant G; MDM4 protein variant Y; MDM4, p53 regulator; MDM4-related protein 1; Mdmx; MGC132766; MRP1; p53-binding protein Mdm4; Protein Mdm4; protein Mdmx; RP11-430C7.1; transformed mouse 3T3 cell double minute 4
Host Species: Rabbit
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 4194
Content And Storage: 2-8°C
Form: Liquid
Antigen:
MDMX
Classification:
Recombinant Monoclonal
Concentration:
100 μg/mL
Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.:
O15151
Gene Symbols:
MDM4
Immunogen:
Between 125 And 175
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunoprecipitation, Western Blot
Clone:
BL-3-2F2
Conjugate:
Unconjugated
Gene:
MDM4
Gene Alias:
4933417N07Rik; AA414968; AL023055; AU018793; AU021806; C85810; DKFZp781B1423; double minute 4 homolog; double minute 4 protein; double minute 4, human homolog of; p53-binding protein; HDMX; human homolog of; Mdm2-like p53-binding protein; MDM4; Mdm4 p53 binding protein homolog; MDM4 protein variant G; MDM4 protein variant Y; MDM4, p53 regulator; MDM4-related protein 1; Mdmx; MGC132766; MRP1; p53-binding protein Mdm4; Protein Mdm4; protein Mdmx; RP11-430C7.1; transformed mouse 3T3 cell double minute 4
Host Species:
Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
4194
Content And Storage:
2-8°C
Form:
Liquid
Antigen: MDMX
Classification: Recombinant Monoclonal
Concentration: 100 μg/mL
Formulation: BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.: O15151
Gene Symbols: MDM4
Immunogen: Between 125 And 175
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunoprecipitation, Western Blot
Clone: BL-3-2F2
Conjugate: Unconjugated
Gene: MDM4
Gene Alias: 4933417N07Rik; AA414968; AL023055; AU018793; AU021806; C85810; DKFZp781B1423; double minute 4 homolog; double minute 4 protein; double minute 4, human homolog of; p53-binding protein; HDMX; human homolog of; Mdm2-like p53-binding protein; MDM4; Mdm4 p53 binding protein homolog; MDM4 protein variant G; MDM4 protein variant Y; MDM4, p53 regulator; MDM4-related protein 1; Mdmx; MGC132766; MRP1; p53-binding protein Mdm4; Protein Mdm4; protein Mdmx; RP11-430C7.1; transformed mouse 3T3 cell double minute 4
Host Species: Rabbit
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 4194
Content And Storage: 2-8°C
Form: Liquid
Antigen:
MDMX
Classification:
Recombinant Monoclonal
Concentration:
100 μg/mL
Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.:
O15151
Gene Symbols:
MDM4
Immunogen:
Between 125 And 175
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunoprecipitation, Western Blot
Clone:
BL-3-2F2
Conjugate:
Unconjugated
Gene:
MDM4
Gene Alias:
4933417N07Rik; AA414968; AL023055; AU018793; AU021806; C85810; DKFZp781B1423; double minute 4 homolog; double minute 4 protein; double minute 4, human homolog of; p53-binding protein; HDMX; human homolog of; Mdm2-like p53-binding protein; MDM4; Mdm4 p53 binding protein homolog; MDM4 protein variant G; MDM4 protein variant Y; MDM4, p53 regulator; MDM4-related protein 1; Mdmx; MGC132766; MRP1; p53-binding protein Mdm4; Protein Mdm4; protein Mdmx; RP11-430C7.1; transformed mouse 3T3 cell double minute 4
Host Species:
Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
4194
Content And Storage:
2-8°C
Form:
Liquid
Antigen: HIF-1 alpha
Classification: Recombinant Monoclonal
Concentration: 0.4 mg/mL
Formulation: BBS with 0.1% BSA and 0.09% sodium azide, pH 8.2
Gene Accession No.: Q16665
Gene Symbols: HIF1A
Immunogen: Between 433 And 826
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: BL-124-3F7
Conjugate: Unconjugated
Gene: HIF1A
Gene Alias: AA959795; ARNT interacting protein; ARNT2; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; bHLHe78; Class E basic helix-loop-helix protein 78; HIF; hif 1; hif 1a; HIF1; HIF1 alpha; HIF-1 alpha; HIF1a; hif-1a; hif1a.L; HIF1alpha; HIF-1alpha; HIF-1-alpha; HIF1-alpha; HIF1-alpha protein; hypoxia inducible factor 1 alpha; hypoxia inducible factor 1 alpha subunit; hypoxia inducible factor 1 alpha subunit L homeolog; hypoxia inducible factor 1 subunit alpha; hypoxia inducible factor 1 subunit alpha L homeolog; hypoxia inducible factor 1, alpha subunit; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia inducible factor-1 alpha; hypoxia-inducible factor 1 alpha; hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1 alpha subunit; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) L homeolog; hypoxia-inducible factor 1-alpha; hypoxia-inducible factor-1 alpha; hypoxia-inducible factor1alpha; member of PAS protein 1; member of PAS superfamily 1; MOP1; PAS domain-containing protein 8; PASD8; XELAEV_18039792mg; XELAEV_18041137mg; xhif1a
Host Species: Rabbit
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 3091
Content And Storage: 2-8°C
Form: Liquid
Antigen:
HIF-1 alpha
Classification:
Recombinant Monoclonal
Concentration:
0.4 mg/mL
Formulation:
BBS with 0.1% BSA and 0.09% sodium azide, pH 8.2
Gene Accession No.:
Q16665
Gene Symbols:
HIF1A
Immunogen:
Between 433 And 826
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
BL-124-3F7
Conjugate:
Unconjugated
Gene:
HIF1A
Gene Alias:
AA959795; ARNT interacting protein; ARNT2; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; bHLHe78; Class E basic helix-loop-helix protein 78; HIF; hif 1; hif 1a; HIF1; HIF1 alpha; HIF-1 alpha; HIF1a; hif-1a; hif1a.L; HIF1alpha; HIF-1alpha; HIF-1-alpha; HIF1-alpha; HIF1-alpha protein; hypoxia inducible factor 1 alpha; hypoxia inducible factor 1 alpha subunit; hypoxia inducible factor 1 alpha subunit L homeolog; hypoxia inducible factor 1 subunit alpha; hypoxia inducible factor 1 subunit alpha L homeolog; hypoxia inducible factor 1, alpha subunit; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia inducible factor-1 alpha; hypoxia-inducible factor 1 alpha; hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1 alpha subunit; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) L homeolog; hypoxia-inducible factor 1-alpha; hypoxia-inducible factor-1 alpha; hypoxia-inducible factor1alpha; member of PAS protein 1; member of PAS superfamily 1; MOP1; PAS domain-containing protein 8; PASD8; XELAEV_18039792mg; XELAEV_18041137mg; xhif1a
Host Species:
Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
3091
Content And Storage:
2-8°C
Form:
Liquid
Antigen: HIF-2 alpha
Classification: Recombinant Monoclonal
Concentration: 0.4 mg/mL
Formulation: BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.: Q99814
Gene Symbols: EPAS1
Immunogen: Between 400 And 450
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: BL-95-1A2
Conjugate: Unconjugated
Gene: EPAS1
Gene Alias: basic-helix-loop-helix-PAS protein MOP2; bHLHe73; Class E basic helix-loop-helix protein 73; ECYT4; endothelial PAS domain protein 1; endothelial PAS domain protein 1b; endothelial PAS domain-containing protein 1; endothelial PAS domain-containing protein 1b; EPAS; Epas1; EPAS-1; epas1b; Hif like protein; HIF1 alpha-like factor; HIF-1-alpha-like factor; HIF-1alpha-like factor; HIF1alpha-like factor; HIF2 alpha; HIF-2 alpha; HIF2A; hif-2a; hif-2ab; HIF-2alpha; HIF-2-alpha; HIF2-alpha; HIF-related factor; HLF; HLF (HIF1alpha-like factor); HRF; hypoxia inducible factor 2 alpha; hypoxia inducible factor 2, alpha subunit; hypoxia inducible factor 2a; hypoxia inducible transcription factor 2alpha; hypoxia-inducible factor 2 alpha; hypoxia-inducible factor 2-alpha; Member of PAS protein 2; mHLF; MOP2; PAS domain-containing protein 2; PASD2; wu:fq36f01
Host Species: Rabbit
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 2034
Content And Storage: 2-8°C
Form: Liquid
Antigen:
HIF-2 alpha
Classification:
Recombinant Monoclonal
Concentration:
0.4 mg/mL
Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.:
Q99814
Gene Symbols:
EPAS1
Immunogen:
Between 400 And 450
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
BL-95-1A2
Conjugate:
Unconjugated
Gene:
EPAS1
Gene Alias:
basic-helix-loop-helix-PAS protein MOP2; bHLHe73; Class E basic helix-loop-helix protein 73; ECYT4; endothelial PAS domain protein 1; endothelial PAS domain protein 1b; endothelial PAS domain-containing protein 1; endothelial PAS domain-containing protein 1b; EPAS; Epas1; EPAS-1; epas1b; Hif like protein; HIF1 alpha-like factor; HIF-1-alpha-like factor; HIF-1alpha-like factor; HIF1alpha-like factor; HIF2 alpha; HIF-2 alpha; HIF2A; hif-2a; hif-2ab; HIF-2alpha; HIF-2-alpha; HIF2-alpha; HIF-related factor; HLF; HLF (HIF1alpha-like factor); HRF; hypoxia inducible factor 2 alpha; hypoxia inducible factor 2, alpha subunit; hypoxia inducible factor 2a; hypoxia inducible transcription factor 2alpha; hypoxia-inducible factor 2 alpha; hypoxia-inducible factor 2-alpha; Member of PAS protein 2; mHLF; MOP2; PAS domain-containing protein 2; PASD2; wu:fq36f01
Host Species:
Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
2034
Content And Storage:
2-8°C
Form:
Liquid