PIMA544255

CD86 (B7-2) Recombinant Rabbit Monoclonal Antibody (BLR030F), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA544255-Each-of-1 In Stock ₹ 40,726.56

PIMA544255 - Each of 1

₹ 40,726.56

In Stock

Quantity

1

Base Price: ₹ 40,726.56

GST (18%): ₹ 7,330.781

Total Price: ₹ 48,057.341

Antigen

CD86 (B7-2)

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

BBS with 0.09% sodium azide, pH 8.2

Gene Accession No.

P42081

Gene Symbols

CD86

Immunogen

Between 300 To 329

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

BLR030F

Conjugate

Unconjugated

Gene

CD86

Gene Alias

activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

Host Species

Rabbit

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

942

Content And Storage

2-8°C

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA544256

--

Img

Thermo Scientific

PIMA547842

--

Img

Thermo Scientific

PIMA536075

--

Img

Thermo Scientific

PIMA535200

--

Img

Novus Biologicals

NB10065929X

--

Img

Novus Biologicals

NB10065929V

--

Img

Novus Biologicals

NB488861

--

Img

Novus Biologicals

NP23408A32

--

Description

  • Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections
  • CD86 is one of two ligands (the other CD80) for CTLA4 and CD28
  • CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation
  • Antigen presentation in the absence of sufficient co-stimulation involving CD86/CD80 can induce tolerance
  • CD80 appears to play a role distinct from CD80 in T helper cell differentiation
  • CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily
  • The CD86 protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4
  • Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell
  • Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response
  • Alternative splicing results in two transcript variants encoding different isoforms of CD86
  • Additional transcript variants have been described for CD86, but their full-length sequences have not been determined
  • Diseases associated with CD86 dysfunction include gallbladder squamous cell carcinoma and myocarditis.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA544255

--


Antigen:
CD86 (B7-2)

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
BBS with 0.09% sodium azide, pH 8.2

Gene Accession No.:
P42081

Gene Symbols:
CD86

Immunogen:
Between 300 To 329

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
BLR030F

Conjugate:
Unconjugated

Gene:
CD86

Gene Alias:
activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
942

Content And Storage:
2-8°C

Form:
Liquid

Img

Thermo Scientific

PIMA544256

--


Antigen:
CD86 (B7-2)

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
BBS with 0.09% sodium azide, pH 8.2

Gene Accession No.:
P42081

Gene Symbols:
CD86

Immunogen:
Between 300 To 329

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
BLR030F

Conjugate:
Unconjugated

Gene:
CD86

Gene Alias:
activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
942

Content And Storage:
2-8°C

Form:
Liquid

Img

Thermo Scientific

PIMA544258

--


Antigen:
IDO1

Classification:
Recombinant Monoclonal

Concentration:
50 μg/mL

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6

Gene Accession No.:
P14902

Gene Symbols:
Ido1

Immunogen:
Residues 1-403 (Full Length)

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
BLR031F

Conjugate:
Unconjugated

Gene:
Ido1

Gene Alias:
EC 1.13.11.52; IDO; IDO1; IDO-1; INDO; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine; indoleamine 2,3-dioxygenase 1; indoleamine 23-dioxygenase; Indoleamine-2; indoleamine-pyrrole 2,3 dioxygenase; indoleamine-pyrrole 2,3-dioxygenase

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
3620

Content And Storage:
2-8°C

Form:
Liquid

Img

Thermo Scientific

PIMA544263

--


Antigen:
FOXP3

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
BBS with 0.09% sodium azide, pH 8.2

Gene Accession No.:
Q9BZS1

Gene Symbols:
Foxp3

Immunogen:
Between 275 And 325

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
BLR034F

Conjugate:
Unconjugated

Gene:
Foxp3

Gene Alias:
AIID; DIETER; forkhead box P3; forkhead box protein P3; Forkhead box protein P3 41 kDa form; Forkhead box protein P3, C-terminally processed; forkhead/winged helix transcription factor 3; Foxp3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; regulatory protein Foxp3; RGD1562112; RP23-54C14.1; scurfin; scurfy; sf; XPID

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
50943

Content And Storage:
2-8°C

Form:
Liquid