PIMA544294
SETX Recombinant Rabbit Monoclonal Antibody (BLR050F), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA544294-Each-of-1 | In Stock | ₹ 13,492.81 |
PIMA544294 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 13,492.81
GST (18%): ₹ 2,428.706
Total Price: ₹ 15,921.516
Antigen
SETX
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
BBS with 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.
Q7Z333
Gene Symbols
SETX
Immunogen
Between 900 And 950
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunoprecipitation, Western Blot
Clone
BLR050F
Conjugate
Unconjugated
Gene
SETX
Gene Alias
A130090N03; A930037J23Rik; Als4; amyotrophic lateral sclerosis 4 homolog; amyotrophic lateral sclerosis 4 protein; Amyotrophic lateral sclerosis 4 protein homolog; AOA2; AW060766; bA479K20.2; DEAxQ-box helicase; KIAA0625; mKIAA0625; Probable helicase senataxin; RGD1565575; SCAR1; Sen1; SEN1 homolog; senataxin; Setx; tRNA splicing endonuclease regulator 1
Host Species
Rabbit
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
23064
Content And Storage
2-8°C
Form
Liquid
Description
- Probable RNA/DNA helicase involved in diverse aspects of RNA metabolism and genomic integrity
- Plays a role in transcription regulation by its ability to modulate RNA Polymerase II (Pol II) binding to chromatin and through its interaction with proteins involved in transcription (PubMed:19515850, PubMed:21700224)
- Contributes to the mRNA splicing efficiency and splice site selection (PubMed:19515850)
- Required for the resolution of R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site, allowing XRN2 recruitment and XRN2-mediated degradation of the downstream cleaved RNA and hence efficient RNA polymerase II (RNAp II) transcription termination (PubMed:19515850, PubMed:21700224, PubMed:26700805)
- Required for the 3' transcriptional termination of PER1 and CRY2, thus playing an important role in the circadian rhythm regulation
- Involved in DNA double-strand breaks damage response generated by oxidative stress (PubMed:17562789)
- In association with RRP45, targets the RNA exosome complex to sites of transcription-induced DNA damage (PubMed:24105744)
- Plays a role in the development and maturation of germ cells: essential for male meiosis, acting at the interface of transcription and meiotic recombination, and in the process of gene silencing during meiotic sex chromosome inactivation (MSCI)
- May be involved in telomeric stability through the regulation of telomere repeat-containing RNA (TERRA) transcription (PubMed:21112256)
- Plays a role in neurite outgrowth in hippocampal cells through FGF8-activated signaling pathways
- Inhibits retinoic acid-induced apoptosis (PubMed:21576111).
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Antigen: SETX
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: BBS with 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.: Q7Z333
Gene Symbols: SETX
Immunogen: Between 900 And 950
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation, Western Blot
Clone: BLR050F
Conjugate: Unconjugated
Gene: SETX
Gene Alias: A130090N03; A930037J23Rik; Als4; amyotrophic lateral sclerosis 4 homolog; amyotrophic lateral sclerosis 4 protein; Amyotrophic lateral sclerosis 4 protein homolog; AOA2; AW060766; bA479K20.2; DEAxQ-box helicase; KIAA0625; mKIAA0625; Probable helicase senataxin; RGD1565575; SCAR1; Sen1; SEN1 homolog; senataxin; Setx; tRNA splicing endonuclease regulator 1
Host Species: Rabbit
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 23064
Content And Storage: 2-8°C
Form: Liquid
Antigen:
SETX
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
BBS with 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.:
Q7Z333
Gene Symbols:
SETX
Immunogen:
Between 900 And 950
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation, Western Blot
Clone:
BLR050F
Conjugate:
Unconjugated
Gene:
SETX
Gene Alias:
A130090N03; A930037J23Rik; Als4; amyotrophic lateral sclerosis 4 homolog; amyotrophic lateral sclerosis 4 protein; Amyotrophic lateral sclerosis 4 protein homolog; AOA2; AW060766; bA479K20.2; DEAxQ-box helicase; KIAA0625; mKIAA0625; Probable helicase senataxin; RGD1565575; SCAR1; Sen1; SEN1 homolog; senataxin; Setx; tRNA splicing endonuclease regulator 1
Host Species:
Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
23064
Content And Storage:
2-8°C
Form:
Liquid
Antigen: CD137 (4-1BB)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: BBS with 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.: Q07011
Gene Symbols: TNFRSF9
Immunogen: Residues 24-189 (Ecd)
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: BLR051F
Conjugate: Unconjugated
Gene: TNFRSF9
Gene Alias: 4 1 BB; 41BB; 4-1BB; 4-1BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; EGK_00183; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; Ly63; receptor protein 4-1BB; s4 1 BB; s4 1BB; s41BB; sCD137; secreted CD137 antigen; soluble 4 1 BB; soluble 4 1BB; soluble 41BB; soluble CD137; T cell antigen ILA; T-cell antigen 4-1BB; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNF receptor superfamily member 9; TNFRSF9; Tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily, member 9
Host Species: Rabbit
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 3604
Content And Storage: 2-8°C
Form: Liquid
Antigen:
CD137 (4-1BB)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
BBS with 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.:
Q07011
Gene Symbols:
TNFRSF9
Immunogen:
Residues 24-189 (Ecd)
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
BLR051F
Conjugate:
Unconjugated
Gene:
TNFRSF9
Gene Alias:
4 1 BB; 41BB; 4-1BB; 4-1BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; EGK_00183; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; Ly63; receptor protein 4-1BB; s4 1 BB; s4 1BB; s41BB; sCD137; secreted CD137 antigen; soluble 4 1 BB; soluble 4 1BB; soluble 41BB; soluble CD137; T cell antigen ILA; T-cell antigen 4-1BB; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNF receptor superfamily member 9; TNFRSF9; Tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily, member 9
Host Species:
Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
3604
Content And Storage:
2-8°C
Form:
Liquid
Antigen: RAD21
Classification: Recombinant Monoclonal
Concentration: 40 μg/mL
Formulation: BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.: O60216, Q61550
Gene Symbols: Rad21
Immunogen: Between 581 And 631 (C-Term)
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Western Blot
Clone: BLR052F
Conjugate: Unconjugated
Gene: Rad21
Gene Alias: 64-kDa carboxy-terminal product; 64-kDa C-terminal product; 65-kDa carboxy-terminal product; CDLS4; double-strand-break repair protein rad21 homolog; double-strand-break repair protein rad21-like protein; FLJ25655; FLJ40596; h NXP-1; hHR21; HR21; HRAD21; KIAA0078; KIAA0078RAD21; kleisin; MCD1; mHR21; mKIAA0078; nuclear matrix protein 1; NXP1; NXP-1; Pokeweed agglutinin-binding protein 29; protein involved in DNA double-strand break repair; PW29; Rad21; RAD21 cohesin complex component; RAD21 homolog; RAD21 homolog (S. pombe); SCC1; SCC1 homolog; sister chromatid cohesion 1
Host Species: Rabbit
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 19357, 5885
Content And Storage: 2-8°C
Form: Liquid
Antigen:
RAD21
Classification:
Recombinant Monoclonal
Concentration:
40 μg/mL
Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.:
O60216, Q61550
Gene Symbols:
Rad21
Immunogen:
Between 581 And 631 (C-Term)
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Western Blot
Clone:
BLR052F
Conjugate:
Unconjugated
Gene:
Rad21
Gene Alias:
64-kDa carboxy-terminal product; 64-kDa C-terminal product; 65-kDa carboxy-terminal product; CDLS4; double-strand-break repair protein rad21 homolog; double-strand-break repair protein rad21-like protein; FLJ25655; FLJ40596; h NXP-1; hHR21; HR21; HRAD21; KIAA0078; KIAA0078RAD21; kleisin; MCD1; mHR21; mKIAA0078; nuclear matrix protein 1; NXP1; NXP-1; Pokeweed agglutinin-binding protein 29; protein involved in DNA double-strand break repair; PW29; Rad21; RAD21 cohesin complex component; RAD21 homolog; RAD21 homolog (S. pombe); SCC1; SCC1 homolog; sister chromatid cohesion 1
Host Species:
Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
19357, 5885
Content And Storage:
2-8°C
Form:
Liquid
Antigen: Phospho-gamma-H2AX (Ser139)
Classification: Recombinant Monoclonal
Concentration: 100 μg/mL
Formulation: BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2
Gene Accession No.: P16104
Gene Symbols: H2AX
Immunogen: Surrounding Serine 140
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: BLR053F
Conjugate: Unconjugated
Gene: H2AX
Gene Alias: gamma H2A X; gamma H2A.X; gamma-H2A.X; gh2ax
Host Species: Rabbit
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 3014
Content And Storage: 2-8°C
Form: Liquid
Antigen:
Phospho-gamma-H2AX (Ser139)
Classification:
Recombinant Monoclonal
Concentration:
100 μg/mL
Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2
Gene Accession No.:
P16104
Gene Symbols:
H2AX
Immunogen:
Surrounding Serine 140
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
BLR053F
Conjugate:
Unconjugated
Gene:
H2AX
Gene Alias:
gamma H2A X; gamma H2A.X; gamma-H2A.X; gh2ax
Host Species:
Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
3014
Content And Storage:
2-8°C
Form:
Liquid