PIMA544303

CD30 Recombinant Rabbit Monoclonal Antibody (BLR055F), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA544303-Each-of-1 In Stock ₹ 42,309.42

PIMA544303 - Each of 1

₹ 42,309.42

In Stock

Quantity

1

Base Price: ₹ 42,309.42

GST (18%): ₹ 7,615.696

Total Price: ₹ 49,925.116

Antigen

CD30

Classification

Recombinant Monoclonal

Concentration

0.25 mg/mL

Formulation

BBS with 0.1% BSA and 0.09% sodium azide, pH 8.2

Gene Accession No.

P28908

Gene Symbols

TNFRSF8

Immunogen

Residues 19-385 (Ecd)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

BLR055F

Conjugate

Unconjugated

Gene

TNFRSF8

Gene Alias

Ber-H2; Cd30; CD30 antigen; CD30 molecule; CD30L receptor; cytokine receptor CD30; D1S166E; Ki; Ki-1; Ki-1 antigen; Lymphocyte activation antigen CD30; sCD30; soluble CD30; TNF receptor superfamily member 8; TNFRSF8; Tumor necrosis factor receptor superfamily member 8; tumor necrosis factor receptor superfamily, member 8; Tumor necrosis factor superfamily member 8; tumor necrosis factor superfamily, member CD30

Host Species

Rabbit

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

943

Content And Storage

2-8°C

Form

Liquid

Description

  • Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections
  • CD30 (Ki-1, TNF Receptor Superfamily Member 8) is a type I transmembrane glycoprotein of the TNF receptor superfamily
  • CD30 was originally identified as a cell surface antigen of Hodgkins and Reed-Sternberg cells using monoclonal antibody Ki-1
  • The ligand for CD30 is CD30L (CD153)
  • The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death
  • CD30 has a critical role in the pathophysiology of Hodgkin's disease and other CD30+ lymphomas
  • CD30 acts as a costimulatory molecule in thymic negative selection
  • In addition to its expression on Hodgkin's and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin's lymphomas (including Burkitt's lymphomas), virus-infected T and B cells, and on normal T and B cells after activation
  • In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that co-express CD45RO and the IL4 receptor
  • Soluble form of CD30 (sCD30) serves as a marker reflecting Th2 immune response
  • TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB
  • CD30 is a positive regulator of apoptosis, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity
  • Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported
  • CD30 is expressed by mononuclear cells in Hodgkin's lymphoma, Reed Sternberg cells and most Anaplastic Large Cell Lymphomas (ALCL)
  • CD30 is also expressed by embryonal carcinomas.

Compare Similar Items

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Img

Thermo Scientific

PIMA544303

--


Antigen:
CD30

Classification:
Recombinant Monoclonal

Concentration:
0.25 mg/mL

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide, pH 8.2

Gene Accession No.:
P28908

Gene Symbols:
TNFRSF8

Immunogen:
Residues 19-385 (Ecd)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
BLR055F

Conjugate:
Unconjugated

Gene:
TNFRSF8

Gene Alias:
Ber-H2; Cd30; CD30 antigen; CD30 molecule; CD30L receptor; cytokine receptor CD30; D1S166E; Ki; Ki-1; Ki-1 antigen; Lymphocyte activation antigen CD30; sCD30; soluble CD30; TNF receptor superfamily member 8; TNFRSF8; Tumor necrosis factor receptor superfamily member 8; tumor necrosis factor receptor superfamily, member 8; Tumor necrosis factor superfamily member 8; tumor necrosis factor superfamily, member CD30

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
943

Content And Storage:
2-8°C

Form:
Liquid

Img

Thermo Scientific

PIMA544304

--


Antigen:
CD30

Classification:
Recombinant Monoclonal

Concentration:
0.25 mg/mL

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide, pH 8.2

Gene Accession No.:
P28908

Gene Symbols:
TNFRSF8

Immunogen:
Residues 19-385 (Ecd)

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
BLR055F

Conjugate:
Unconjugated

Gene:
TNFRSF8

Gene Alias:
Ber-H2; Cd30; CD30 antigen; CD30 molecule; CD30L receptor; cytokine receptor CD30; D1S166E; Ki; Ki-1; Ki-1 antigen; Lymphocyte activation antigen CD30; sCD30; soluble CD30; TNF receptor superfamily member 8; TNFRSF8; Tumor necrosis factor receptor superfamily member 8; tumor necrosis factor receptor superfamily, member 8; Tumor necrosis factor superfamily member 8; tumor necrosis factor superfamily, member CD30

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
943

Content And Storage:
2-8°C

Form:
Liquid

Img

Thermo Scientific

PIMA544305

--


Antigen:
CD40

Classification:
Recombinant Monoclonal

Concentration:
0.25 mg/mL

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2

Gene Accession No.:
P25942

Gene Symbols:
CD40

Immunogen:
Between 227 And 277 (C-Term)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
BLR056F

Conjugate:
Unconjugated

Gene:
CD40

Gene Alias:
AI326936; B cell surface antigen CD40; B cell-associated molecule; B-cell surface antigen CD40; Bp50; CD antigen CD40; Cd40; CD40 antigen; CD40 antigen (TNF receptor superfamily member 5); CD40 antigen, TNF receptor superfamily member 5; CD40 molecule; CD40 molecule, TNF receptor superfamily member 5; CD40L receptor; CDw40; GP39; HIGM1; I79_006806; IGM; IMD3; Immunoglobulin M; ImmunoglobulinM; membrane protein CD40; MGC9013; p50; receptor for ligand CD154; sCD40; soluble CD40; T-BAM; T-cell differentiation antigen; Tnfrsf5; TRAP; tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily, member 5

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
958

Content And Storage:
2-8°C

Form:
Liquid

Img

Thermo Scientific

PIMA544306

--


Antigen:
CD40

Classification:
Recombinant Monoclonal

Concentration:
0.25 mg/mL

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2

Gene Accession No.:
P25942

Gene Symbols:
CD40

Immunogen:
Between 227 And 277 (C-Term)

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
BLR056F

Conjugate:
Unconjugated

Gene:
CD40

Gene Alias:
AI326936; B cell surface antigen CD40; B cell-associated molecule; B-cell surface antigen CD40; Bp50; CD antigen CD40; Cd40; CD40 antigen; CD40 antigen (TNF receptor superfamily member 5); CD40 antigen, TNF receptor superfamily member 5; CD40 molecule; CD40 molecule, TNF receptor superfamily member 5; CD40L receptor; CDw40; GP39; HIGM1; I79_006806; IGM; IMD3; Immunoglobulin M; ImmunoglobulinM; membrane protein CD40; MGC9013; p50; receptor for ligand CD154; sCD40; soluble CD40; T-BAM; T-cell differentiation antigen; Tnfrsf5; TRAP; tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily, member 5

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
958

Content And Storage:
2-8°C

Form:
Liquid