PIMA544311
Histone H2A.X Recombinant Rabbit Monoclonal Antibody (BLR059F), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA544311-Each-of-1 | In Stock | ₹ 40,726.56 |
PIMA544311 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,726.56
GST (18%): ₹ 7,330.781
Total Price: ₹ 48,057.341
Antigen
Histone H2A.X
Classification
Recombinant Monoclonal
Concentration
100 μg/mL
Formulation
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.
P16104
Gene Symbols
H2AX
Immunogen
Between 93 And 143 (C-Term)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
BLR059F
Conjugate
Unconjugated
Gene
H2AX
Gene Alias
AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2A.X; H2A.X variant histone; H2A/X; h2afx; H2ax; H2AX histone; Hist5-2ax; histone 5 protein 2ax; histone H2A.x; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329
Host Species
Rabbit
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
3014
Content And Storage
2-8°C
Form
Liquid
Description
- Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections
- Histone H2A.X (H2AX) is a member of the histone H2A family which is one of the four core histones making up the nucleosome core particle
- In eukaryotes, DNA double strand breaks (DSBs) have been shown to trigger the phosphorylation of serine 139 at the carboxy terminus of histone H2AX resulting in gamma-H2AX
- The phosphorylation of H2AX can be detected by Western blotting or immunofluorescence, revealing the frequency of DSBs
- The phosphatidylinositol 3-kinases have been implicated in H2AX phosphorylation, but it is unclear if ATM is the primary H2AX kinase or if other members of the family such as DNA-PK and ATR contribute in a similar manner
- Structurally, H2A.x contains 143 amino acid residues
- Histone H2A.X is considered a basal histone, being synthesized in G1 as well as in S-phase, and its mRNA contains polyA addition motifs and a polyA tail along with the conserved stem-loop and U7 binding sequences involved in the processing and stability of replication type histone mRNAs
- There are two forms of Histone H2A.X mRNA, one about 1600 bases long and contains polyA; the other about 575 bases long, lacking polyA
- The short form behaves as a replication type histone mRNA, while the longer behaves as a basal type histone mRNA
- Histone H2A.X maps to the 11q23.2-q23.3 region of the human chromosome
- Histone H2A.x contributes to histone-formation and therefore the structure of DNA
- Histone H2A variant H2A.x specifically regulates the interaction of MDC1 (mediator of DNA damage checkpoint protein 1), a DNA repair protein to the sites of DNA damage.
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Antigen: Histone H2A.X
Classification: Recombinant Monoclonal
Concentration: 100 μg/mL
Formulation: BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.: P16104
Gene Symbols: H2AX
Immunogen: Between 93 And 143 (C-Term)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: BLR059F
Conjugate: Unconjugated
Gene: H2AX
Gene Alias: AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2A.X; H2A.X variant histone; H2A/X; h2afx; H2ax; H2AX histone; Hist5-2ax; histone 5 protein 2ax; histone H2A.x; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329
Host Species: Rabbit
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 3014
Content And Storage: 2-8°C
Form: Liquid
Antigen:
Histone H2A.X
Classification:
Recombinant Monoclonal
Concentration:
100 μg/mL
Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.:
P16104
Gene Symbols:
H2AX
Immunogen:
Between 93 And 143 (C-Term)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
BLR059F
Conjugate:
Unconjugated
Gene:
H2AX
Gene Alias:
AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2A.X; H2A.X variant histone; H2A/X; h2afx; H2ax; H2AX histone; Hist5-2ax; histone 5 protein 2ax; histone H2A.x; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329
Host Species:
Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
3014
Content And Storage:
2-8°C
Form:
Liquid
Antigen: Phospho-BCKDHA (Ser292)
Classification: Recombinant Monoclonal
Concentration: 40 μg/mL
Formulation: BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.: P12694, P50136
Gene Symbols: BCKDHA
Immunogen: Surrounding Serine 292
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: BLR060F
Conjugate: Unconjugated
Gene: BCKDHA
Gene Alias: 2-oxoisovalerate dehydrogenase (lipoamide); 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; BCKAD E1[a]; BCKDA; BCKDE1A; BCKDH E1-alpha; BCKDHA; branched chain alpha-ketoacid dehydrogenase subunit E1 alpha; branched chain keto acid dehydrogenase E1 alpha protein; branched chain keto acid dehydrogenase E1, alpha polypeptide; branched chain keto acid dehydrogenase subunit E1, alpha polypeptide; branched chain ketoacid dehydrogenase E1, alpha polypeptide; branched-chain alpha-keto acid dehydrogenase E1 component alpha chain; E1a; MSU; MSUD1; OVD1A
Host Species: Rabbit
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 12039, 593
Content And Storage: 2-8°C
Form: Liquid
Antigen:
Phospho-BCKDHA (Ser292)
Classification:
Recombinant Monoclonal
Concentration:
40 μg/mL
Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.:
P12694, P50136
Gene Symbols:
BCKDHA
Immunogen:
Surrounding Serine 292
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
BLR060F
Conjugate:
Unconjugated
Gene:
BCKDHA
Gene Alias:
2-oxoisovalerate dehydrogenase (lipoamide); 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; BCKAD E1[a]; BCKDA; BCKDE1A; BCKDH E1-alpha; BCKDHA; branched chain alpha-ketoacid dehydrogenase subunit E1 alpha; branched chain keto acid dehydrogenase E1 alpha protein; branched chain keto acid dehydrogenase E1, alpha polypeptide; branched chain keto acid dehydrogenase subunit E1, alpha polypeptide; branched chain ketoacid dehydrogenase E1, alpha polypeptide; branched-chain alpha-keto acid dehydrogenase E1 component alpha chain; E1a; MSU; MSUD1; OVD1A
Host Species:
Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
12039, 593
Content And Storage:
2-8°C
Form:
Liquid
Antigen: CD33
Classification: Recombinant Monoclonal
Concentration: 100 μg/mL
Formulation: BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.: P20138
Gene Symbols: CD33
Immunogen: Between 314 And 364 (C-Term)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: BLR061G
Conjugate: Unconjugated
Gene: CD33
Gene Alias: CD33; CD33 antigen; CD33 antigen (gp67); CD33 molecule; CD33 molecule transcript; FLJ00391; gp67; Myeloid cell surface antigen CD33; p67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC3; Siglec-3
Host Species: Rabbit
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 945
Content And Storage: 2-8°C
Form: Liquid
Antigen:
CD33
Classification:
Recombinant Monoclonal
Concentration:
100 μg/mL
Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.:
P20138
Gene Symbols:
CD33
Immunogen:
Between 314 And 364 (C-Term)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
BLR061G
Conjugate:
Unconjugated
Gene:
CD33
Gene Alias:
CD33; CD33 antigen; CD33 antigen (gp67); CD33 molecule; CD33 molecule transcript; FLJ00391; gp67; Myeloid cell surface antigen CD33; p67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC3; Siglec-3
Host Species:
Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
945
Content And Storage:
2-8°C
Form:
Liquid
Antigen: CD33
Classification: Recombinant Monoclonal
Concentration: 100 μg/mL
Formulation: BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.: P20138
Gene Symbols: CD33
Immunogen: Between 314 And 364 (C-Term)
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: BLR061G
Conjugate: Unconjugated
Gene: CD33
Gene Alias: CD33; CD33 antigen; CD33 antigen (gp67); CD33 molecule; CD33 molecule transcript; FLJ00391; gp67; Myeloid cell surface antigen CD33; p67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC3; Siglec-3
Host Species: Rabbit
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 945
Content And Storage: 2-8°C
Form: Liquid
Antigen:
CD33
Classification:
Recombinant Monoclonal
Concentration:
100 μg/mL
Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.:
P20138
Gene Symbols:
CD33
Immunogen:
Between 314 And 364 (C-Term)
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
BLR061G
Conjugate:
Unconjugated
Gene:
CD33
Gene Alias:
CD33; CD33 antigen; CD33 antigen (gp67); CD33 molecule; CD33 molecule transcript; FLJ00391; gp67; Myeloid cell surface antigen CD33; p67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC3; Siglec-3
Host Species:
Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
945
Content And Storage:
2-8°C
Form:
Liquid