PIMA544458

MACC1 Recombinant Rabbit Monoclonal Antibody (BLR135H), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA544458-Each-of-1 In Stock ₹ 13,492.81

PIMA544458 - Each of 1

₹ 13,492.81

In Stock

Quantity

1

Base Price: ₹ 13,492.81

GST (18%): ₹ 2,428.706

Total Price: ₹ 15,921.516

Antigen

MACC1

Classification

Recombinant Monoclonal

Concentration

0.25 mg/mL

Formulation

BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6

Gene Accession No.

Q6ZN28

Gene Symbols

MACC1

Immunogen

Between 100 And 150

Quantity

10 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

BLR135H

Conjugate

Unconjugated

Gene

MACC1

Gene Alias

4732474O15Rik; 7A5; Gm267; MACC1; metastasis associated in colon cancer 1; metastasis-associated in colon cancer protein 1; putative binding protein 7a5; RGD1309838; SH3 domain-containing protein 7a5; SH3BP4L

Host Species

Rabbit

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

346389

Content And Storage

2-8°C

Form

Liquid

Description

  • Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections
  • MACC1 (Metastasis associated in colon cancer 1) is a key regulator of the hepatocyte growth factor (HGF)-HGF receptor (MET) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis
  • MACC1 protein consists of four domains: ZU5, SH3, and two C-terminal death domains (DD)
  • Expression of MACC1 was found significantly upregulated in malignant tissues (colon cancer of all stages as well as liver and lung metastases) compared to normal tissues or adenomas
  • MACC1 represents an early and crucial prognostic indicator for colon cancer metastasis that is independent of age, sex, tumor infiltration, nodal status, and lymph vessel invasion
  • Besides its involvement in signal transduction with the MET receptor, MACC1 also links MET signaling and apoptosis
  • MACC1 may also be an important therapeutic target for colorectal cancer treatment
  • At least two isoforms of MACC1 are known to exist.

Compare Similar Items

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Img

Thermo Scientific

PIMA544458

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Antigen:
MACC1

Classification:
Recombinant Monoclonal

Concentration:
0.25 mg/mL

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6

Gene Accession No.:
Q6ZN28

Gene Symbols:
MACC1

Immunogen:
Between 100 And 150

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
BLR135H

Conjugate:
Unconjugated

Gene:
MACC1

Gene Alias:
4732474O15Rik; 7A5; Gm267; MACC1; metastasis associated in colon cancer 1; metastasis-associated in colon cancer protein 1; putative binding protein 7a5; RGD1309838; SH3 domain-containing protein 7a5; SH3BP4L

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
346389

Content And Storage:
2-8°C

Form:
Liquid

Img

Thermo Scientific

PIMA544460

--


Antigen:
EphA2

Classification:
Recombinant Monoclonal

Concentration:
40 μg/mL

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6

Gene Accession No.:
P29317

Gene Symbols:
EPHA2

Immunogen:
Residues 25-534 (Ecd)

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Clone:
BLR136H

Conjugate:
Unconjugated

Gene:
EPHA2

Gene Alias:
ARCC2; AW545284; CTPA; CTPP1; CTRCT6; Eck; EPH receptor A2; Epha2; ephrin receptor EphA2; Ephrin type-A receptor 2; Epithelial cell kinase; epithelial cell receptor protein tyrosine kinase; I79_019726; Myk2; Sek2; Sek-2; soluble EPHA2 variant 1; tyrosine-protein kinase receptor ECK; Tyrosine-protein kinase receptor MPK-5; tyrosine-protein kinase receptor SEK-2

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
1969

Content And Storage:
2-8°C

Form:
Liquid

Img

Thermo Scientific

PIMA544463

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Antigen:
CD11c

Classification:
Recombinant Monoclonal

Concentration:
100 μg/mL

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide, pH 8.2

Gene Accession No.:
P20702

Gene Symbols:
Itgax

Immunogen:
Residues 112-355 (Ecd)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
BLR138H

Conjugate:
Unconjugated

Gene:
Itgax

Gene Alias:
AI449405; CD11 antigen-like family member C; CD11c; CD11C (p150) alpha polypeptide; complement component 3 receptor 4 subunit; complement receptor 4; Cr4; integrin alpha X; integrin alpha-X; integrin aX; integrin subunit alpha X; integrin, alpha X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); Itgax; Leu M5; leu M5, alpha subunit; leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; leukocyte surface antigen p150,95, alpha subunit; myeloid membrane antigen, alpha subunit; N418; p150 95 integrin alpha chain; RGD1561123; SLEB6

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
3687

Content And Storage:
2-8°C

Form:
Liquid

Img

Thermo Scientific

PIMA544464

--


Antigen:
CD11c

Classification:
Recombinant Monoclonal

Concentration:
100 μg/mL

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide, pH 8.2

Gene Accession No.:
P20702

Gene Symbols:
Itgax

Immunogen:
Residues 112-355 (Ecd)

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
BLR138H

Conjugate:
Unconjugated

Gene:
Itgax

Gene Alias:
AI449405; CD11 antigen-like family member C; CD11c; CD11C (p150) alpha polypeptide; complement component 3 receptor 4 subunit; complement receptor 4; Cr4; integrin alpha X; integrin alpha-X; integrin aX; integrin subunit alpha X; integrin, alpha X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); Itgax; Leu M5; leu M5, alpha subunit; leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; leukocyte surface antigen p150,95, alpha subunit; myeloid membrane antigen, alpha subunit; N418; p150 95 integrin alpha chain; RGD1561123; SLEB6

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
3687

Content And Storage:
2-8°C

Form:
Liquid