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PIMA544493

CD8 alpha Recombinant Rabbit Monoclonal Antibody (BLR154J), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA544493-Each-of-1 In Stock ₹ 40,726.56

PIMA544493 - Each of 1

₹ 40,726.56

In Stock

Quantity

1

Base Price: ₹ 40,726.56

GST (18%): ₹ 7,330.781

Total Price: ₹ 48,057.341

Antigen

CD8 alpha

Classification

Recombinant Monoclonal

Concentration

0.25 mg/mL

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 6.8-7.4

Gene Accession No.

P01732, P10966

Gene Symbols

Cd8a, CD8B

Immunogen

Residues 22-180 (Ecd)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

BLR154J

Conjugate

Unconjugated

Gene

CD8B

Gene Alias

BB154331; CD8; CD8 alpha; CD8 alpha chain; CD8 alpha chain precursor; CD8 antigen; CD8 antigen 32 kDa chain; CD8 antigen 37 kDa chain; CD8 antigen alpha polypeptide; CD8 antigen alpha protein; CD8 antigen alpha protein precursor; CD8 antigen alpha-chain; CD8 antigen beta polypeptide; CD8 antigen beta polypeptide precursor; CD8 antigen beta-chain; CD8 antigen, alpha chain; CD8 antigen, alpha polypeptide; CD8 antigen, alpha polypeptide (p32); CD8 antigen, alpha-chain; CD8 antigen, beta chain; CD8 antigen, beta chain 1; CD8 antigen, beta polypeptide; CD8 antigen, beta polypeptide 1 (p37); CD8 antigen, beta-chain; CD8 beta; CD8 beta chain; CD8 beta-2; CD8a; CD8A antigen alpha; CD8a molecule; CD8A; T-cell surface glycoprotein; CD8alpha; CD8B; CD8b antigen; CD8b molecule; CD8b molecule pseudogene; Cd8b1; CD8beta; CD8BP; fCD8; LEU2; Leu-2; Leu2 T-lymphocyte antigen; leu-2a; Ly-2; LY3; Ly-3; Ly-35; Ly-B; Ly-C; Lymphocyte antigen 3; Lyt2; Lyt-2; Lyt-2.1 lymphocyte differentiation antigen (AA at 100); Lyt3; Lyt-3; MAL; membrane glycoprotein; membrane protein; OKT8 T-cell antigen; OX-8 membrane antigen; p32; P37; RHACD8-4; T cell co-receptor; T lymphocyte surface glycoprotein beta chain; T8 T-cell antigen; T-cell antigen Leu2; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein Lyt-2; T-cell surface glycoprotein Lyt-3; T-cell surface molecule; T-lymphocyte differentiation antigen T8/Leu-2; type I transmembrane glycoprotein

Host Species

Rabbit

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

925, 926

Content And Storage

2-8°C

Form

Liquid

Description

  • Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections
  • Cluster of differentiation 8 (CD8), a type I transmembrane glycoprotein of the immunoglobulin family of receptors, plays an integral role in signal transduction, and T cell differentiation and activation
  • CD8 is predominantly expressed on T cells as a disulfide-linked heterodimer of CD8alpha and CD8beta, where it functions as a co-receptor, along with T cell receptor (TCR), for major histocompatibilty complex class I (MHC-I) molecules; whereas its counterpart, CD4, acts as a co-receptor for MHC-II molecules
  • CD8 exists on the cell surface, where the CD8alpha chain is essential for binding to MHC-I
  • CD8 is also expressed on a subset of T cells, NK cells, monocytes and dendritic cells as disulfide-linked homodimers of CD8alpha
  • Ligation of MHC-I/peptide complexes presented by antigen-presenting cells (APCs), triggers the recruitment of lymphocyte-specific protein tyrosine kinase (Lck), which leads to lymphokine production, motility and cytotoxic T lymphocyte (CTL) activation
  • Once activated, CTLs play a crucial role in the clearance of pathogens and tumor cells
  • Differentiation of naive CD8+ T cells into CTLs is strongly enhanced by IL-2, IL-12 and TGF-beta1.

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Thermo Scientific

PIMA544493

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Antigen:
CD8 alpha
Classification:
Recombinant Monoclonal
Concentration:
0.25 mg/mL
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 6.8-7.4
Gene Accession No.:
P01732, P10966
Gene Symbols:
Cd8a, CD8B
Immunogen:
Residues 22-180 (Ecd)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
BLR154J
Conjugate:
Unconjugated
Gene:
CD8B
Gene Alias:
BB154331; CD8; CD8 alpha; CD8 alpha chain; CD8 alpha chain precursor; CD8 antigen; CD8 antigen 32 kDa chain; CD8 antigen 37 kDa chain; CD8 antigen alpha polypeptide; CD8 antigen alpha protein; CD8 antigen alpha protein precursor; CD8 antigen alpha-chain; CD8 antigen beta polypeptide; CD8 antigen beta polypeptide precursor; CD8 antigen beta-chain; CD8 antigen, alpha chain; CD8 antigen, alpha polypeptide; CD8 antigen, alpha polypeptide (p32); CD8 antigen, alpha-chain; CD8 antigen, beta chain; CD8 antigen, beta chain 1; CD8 antigen, beta polypeptide; CD8 antigen, beta polypeptide 1 (p37); CD8 antigen, beta-chain; CD8 beta; CD8 beta chain; CD8 beta-2; CD8a; CD8A antigen alpha; CD8a molecule; CD8A; T-cell surface glycoprotein; CD8alpha; CD8B; CD8b antigen; CD8b molecule; CD8b molecule pseudogene; Cd8b1; CD8beta; CD8BP; fCD8; LEU2; Leu-2; Leu2 T-lymphocyte antigen; leu-2a; Ly-2; LY3; Ly-3; Ly-35; Ly-B; Ly-C; Lymphocyte antigen 3; Lyt2; Lyt-2; Lyt-2.1 lymphocyte differentiation antigen (AA at 100); Lyt3; Lyt-3; MAL; membrane glycoprotein; membrane protein; OKT8 T-cell antigen; OX-8 membrane antigen; p32; P37; RHACD8-4; T cell co-receptor; T lymphocyte surface glycoprotein beta chain; T8 T-cell antigen; T-cell antigen Leu2; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein Lyt-2; T-cell surface glycoprotein Lyt-3; T-cell surface molecule; T-lymphocyte differentiation antigen T8/Leu-2; type I transmembrane glycoprotein
Host Species:
Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
925, 926
Content And Storage:
2-8°C
Form:
Liquid

Img

Thermo Scientific

PIMA544495

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Antigen:
Tyrosine Hydroxylase
Classification:
Recombinant Monoclonal
Concentration:
0.25 mg/mL
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 6.8-7.4
Gene Accession No.:
P07101
Gene Symbols:
TH
Immunogen:
Between 450 And 500
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
BLR155J
Conjugate:
Unconjugated
Gene:
TH
Gene Alias:
dystonia 14; DYT14; DYT5b; EC 1.14.16.2; HGNC:11782; Th; TH isoform 3; TH isoform a; th1; TH-4; The; TY3H; TYH; TYH antibody; Tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; tyrosine hydroxylase
Host Species:
Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
7054
Content And Storage:
2-8°C
Form:
Liquid

Img

Thermo Scientific

PIMA544496

--

Antigen:
Tyrosine Hydroxylase
Classification:
Recombinant Monoclonal
Concentration:
0.25 mg/mL
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 6.8-7.4
Gene Accession No.:
P07101
Gene Symbols:
TH
Immunogen:
Between 450 And 500
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
BLR155J
Conjugate:
Unconjugated
Gene:
TH
Gene Alias:
dystonia 14; DYT14; DYT5b; EC 1.14.16.2; HGNC:11782; Th; TH isoform 3; TH isoform a; th1; TH-4; The; TY3H; TYH; TYH antibody; Tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; tyrosine hydroxylase
Host Species:
Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
7054
Content And Storage:
2-8°C
Form:
Liquid

Img

Thermo Scientific

PIMA544498

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Antigen:
TWIST1
Classification:
Recombinant Monoclonal
Concentration:
0.25 mg/mL
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 6.8-7.4
Gene Accession No.:
Q15672
Gene Symbols:
TWIST1
Immunogen:
Between 1 And 50
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
BLR156J
Conjugate:
Unconjugated
Gene:
TWIST1
Gene Alias:
AA960487; ACS3; B-HLH DNA binding protein; bHLHa38; BPES2; BPES3; charlie chaplin; class A basic helix-loop-helix protein 38; CRS; CRS1; CSO; H-twist; M-twist; p ACS3; Pde; pdt; Pluridigite; polydactyly EMS; SCS; Ska<m10Jus>; Ska<sup>m10Jus</sup>; Ska10; Twist; twist basic helix-loop-helix transcription factor 1; twist family bHLH transcription factor 1; twist gene homolog 1; twist homolog 1; TWIST homolog of drosophila; Twist1; twist-related protein 1
Host Species:
Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
7291
Content And Storage:
2-8°C
Form:
Liquid